M. Margarita Behrens

TL;DR: The lack of disruptants of the CKI gene suggests that this protein is essential for the vegetative growth of D. discoideum, and a potential role for this kinase in DNA repair is suggested.

TL;DR: The results suggested that the resting-state phenotypes of cortical theta oscillations unique to Sp4 hypomorphic mice closely mimicked a schizophrenic endophenotype, suggesting separate underlying neural circuit mechanisms.

TL;DR: It is found that conditional loss of the de novo DNA methyltransferase Dnmt3a in mouse excitatory neurons altered expression of synapse-related genes, impaired the maturation of postsynaptic dendritic spines and dampened neuronal excitability, suggesting a complex interaction between two key modes of epigenetic repression of gene expression during brain development that supports cognitive function in adulthood.

TL;DR: In this article, the authors report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex (MOp or M1) as the initial product of the BRAIN Initiative Cell Census Network (BICCN).

TL;DR: In this paper, the de novo DNA methyltransferase Dnmt3a in mouse excitatory neurons altered expression of synapse-related genes, stunted synapse maturation, and impaired working memory and social interest.