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Allan L. Naarden

Researcher at Medical City Dallas Hospital

Publications -  9
Citations -  1763

Allan L. Naarden is an academic researcher from Medical City Dallas Hospital. The author has contributed to research in topics: Tourette syndrome & Genome-wide association study. The author has an hindex of 8, co-authored 8 publications receiving 1294 citations. Previous affiliations of Allan L. Naarden include University of Texas Southwestern Medical Center.

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Journal ArticleDOI

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Phil Lee, +606 more
- 12 Dec 2019 - 
TL;DR: Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes.
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Partitioning the heritability of tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Lea K. Davis, +130 more
- 24 Oct 2013 - 
TL;DR: The results indicate that there is some genetic overlap between these two phenotypically-related neuropsychiatric disorders, but suggest that the two disorders have distinct genetic architectures.
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Genome-wide association study of Tourette's syndrome

Jeremiah M. Scharf, +114 more
- 01 Jun 2013 - 
TL;DR: This study lays the groundwork for the eventual identification of common TS susceptibility variants in larger cohorts and helps to provide a more complete understanding of the full genetic architecture of this disorder.
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Self injurious behaviour in Tourette syndrome: correlates with impulsivity and impulse control

TL;DR: Mild/moderate and severe SIB in TS may represent different phenomena, which has implications for clinical management of these symptoms, and is correlated with variables related to affect or impulse dysregulation.
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Cross-disorder genome-wide analyses suggest a complex genetic relationship between tourette's syndrome and OCD

Dongmei Yu, +164 more
TL;DR: The GWAS signals were enriched for SNPs strongly associated with variations in brain gene expression levels (expression quantitative loci, or eQTLs), suggesting the presence of true functional variants that contribute to risk of these disorders.