Institution
Bar-Ilan University
Education•Ramat Gan, Israel•
About: Bar-Ilan University is a education organization based out in Ramat Gan, Israel. It is known for research contribution in the topics: Population & Poison control. The organization has 12835 authors who have published 34964 publications receiving 995648 citations. The organization is also known as: Bar Ilan University & BIU.
Papers published on a yearly basis
Papers
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TL;DR: This paper showed that the most efficient spreaders are not always necessarily the most connected agents in a network, and that the position of an agent relative to the hierarchical topological organization of the network might be as important as its connectivity.
Abstract: Spreading of information, ideas or diseases can be conveniently modelled in the context of complex networks. An analysis now reveals that the most efficient spreaders are not always necessarily the most connected agents in a network. Instead, the position of an agent relative to the hierarchical topological organization of the network might be as important as its connectivity.
2,618 citations
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TL;DR: This work shows analytically and numerically that for alpha=3 the transition never takes place, unless the network is finite, and finds that the physical structure of the Internet is impressively robust, with p(c)>0.99.
Abstract: A common property of many large networks, including the Internet, is that the connectivity of the various nodes follows a scale-free power-law distribution, P(k) = ck(-alpha). We study the stability of such networks with respect to crashes, such as random removal of sites. Our approach, based on percolation theory, leads to a general condition for the critical fraction of nodes, p(c), that needs to be removed before the network disintegrates. We show analytically and numerically that for alpha 0.99.
2,199 citations
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TL;DR: Findings show that infection with hepatitis C virus is highly dynamic and that early monitoring of viral load can help guide therapy, with blocking efficacies of 81, 95, and 96% for daily doses of 5, 10, and 15 million international units, respectively.
Abstract: To better understand the dynamics of hepatitis C virus and the antiviral effect of interferon-alpha-2b (IFN), viral decline in 23 patients during therapy was analyzed with a mathematical model. The analysis indicates that the major initial effect of IFN is to block virion production or release, with blocking efficacies of 81, 95, and 96% for daily doses of 5, 10, and 15 million international units, respectively. The estimated virion half-life (t1/2) was, on average, 2.7 hours, with pretreatment production and clearance of 10(12) virions per day. The estimated infected cell death rate exhibited large interpatient variation (corresponding t1/2 = 1.7 to 70 days), was inversely correlated with baseline viral load, and was positively correlated with alanine aminotransferase levels. Fast death rates were predictive of virus being undetectable by polymerase chain reaction at 3 months. These findings show that infection with hepatitis C virus is highly dynamic and that early monitoring of viral load can help guide therapy.
2,080 citations
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Celera Corporation1, Centre national de la recherche scientifique2, Cornell University3, National Institutes of Health4, Bar-Ilan University5, TigerLogic6, University of California, Riverside7, Virginia Tech8, University of Notre Dame9, Wellcome Trust Sanger Institute10, University of Maryland Biotechnology Institute11, University of Crete12, European Bioinformatics Institute13, Sapienza University of Rome14, Pasteur Institute15
TL;DR: Analysis of the PEST strain of A. gambiae revealed strong evidence for about 14,000 protein-encoding transcripts, and prominent expansions in specific families of proteins likely involved in cell adhesion and immunity were noted.
Abstract: Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500 million people and causes more than 1 million deaths each year. Tenfold shotgun sequence coverage was obtained from the PEST strain of A. gambiae and assembled into scaffolds that span 278 million base pairs. A total of 91% of the genome was organized in 303 scaffolds; the largest scaffold was 23.1 million base pairs. There was substantial genetic variation within this strain, and the apparent existence of two haplotypes of approximately equal frequency ("dual haplotypes") in a substantial fraction of the genome likely reflects the outbred nature of the PEST strain. The sequence produced a conservative inference of more than 400,000 single-nucleotide polymorphisms that showed a markedly bimodal density distribution. Analysis of the genome sequence revealed strong evidence for about 14,000 protein-encoding transcripts. Prominent expansions in specific families of proteins likely involved in cell adhesion and immunity were noted. An expressed sequence tag analysis of genes regulated by blood feeding provided insights into the physiological adaptations of a hematophagous insect.
2,033 citations
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TL;DR: This review will attempt to address several key questions related to the use of ROS as signaling molecules in cells, including the dynamics and specificity of ROS signaling, networking of ROS with other signaling pathways, ROS signaling within and across different cells, ROS waves and the evolution of the ROS gene network.
1,879 citations
Authors
Showing all 13037 results
Name | H-index | Papers | Citations |
---|---|---|---|
H. Eugene Stanley | 154 | 1190 | 122321 |
Albert-László Barabási | 152 | 438 | 200119 |
Shlomo Havlin | 131 | 1013 | 83347 |
Stuart A. Aaronson | 129 | 657 | 69633 |
Britton Chance | 128 | 1112 | 76591 |
Mark A. Ratner | 127 | 968 | 68132 |
Doron Aurbach | 126 | 797 | 69313 |
Jun Yu | 121 | 1174 | 81186 |
Richard J. Wurtman | 114 | 933 | 53290 |
Amir Lerman | 111 | 877 | 51969 |
Zhu Han | 109 | 1407 | 48725 |
Moussa B.H. Youdim | 107 | 574 | 42538 |
Juan Bisquert | 107 | 450 | 46267 |
Rachel Yehuda | 106 | 461 | 36726 |
Michael F. Green | 106 | 485 | 45707 |