Institution
Harbin Engineering University
Education•Harbin, Heilongjiang, China•
About: Harbin Engineering University is a education organization based out in Harbin, Heilongjiang, China. It is known for research contribution in the topics: Control theory & Computer science. The organization has 31149 authors who have published 27940 publications receiving 276787 citations. The organization is also known as: HEU.
Topics: Control theory, Computer science, Nonlinear system, Artificial neural network, Microstructure
Papers published on a yearly basis
Papers
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TL;DR: Results suggested that Cu(II)-MICA was a material of efficient, low-cost, convenient separation under magnetic field and could be reused five times with about 14% regeneration loss.
178 citations
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TL;DR: This review systematically summarize synthetic strategies for the preparation of g-C3N4-based materials, and outline their recent advances in various biomedical applications such as diagnostic imaging, therapeutic applications, biosensors and antibacterial applications.
177 citations
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TL;DR: In this article, the authors developed biodegradable copper/manganese silicate nanosphere (CMSN)-coated lanthanide-doped nanoparticles (LDNPs) for trimodal imaging-guided CDT/PDT synergistic therapy.
Abstract: Reactive oxygen species (ROS)-based therapeutic modalities including chemodynamic therapy (CDT) and photodynamic therapy (PDT) hold great promise for conquering malignant tumors. However, these two methods tend to be restricted by the overexpressed glutathione (GSH) and hypoxia in the tumor microenvironment (TME). Here, we develop biodegradable copper/manganese silicate nanosphere (CMSN)-coated lanthanide-doped nanoparticles (LDNPs) for trimodal imaging-guided CDT/PDT synergistic therapy. The tridoped Yb3+/Er3+/Tm3+ in the ultrasmall core and the optimal Yb3+/Ce3+ doping in the shell enable the ultrabright dual-mode upconversion (UC) and downconversion (DC) emissions of LDNPs under near-infrared (NIR) laser excitation. The luminescence in the second near-infrared (NIR-II, 1000-1700 nm) window offers deep-tissue penetration, high spatial resolution, and reduced autofluorescence when used for optical imaging. Significantly, the CMSNs are capable of relieving the hypoxic TME through decomposing H2O2 to produce O2, which can react with the sample to generate 1O2 upon excitation of UC photons (PDT). The GSH-triggered degradation of CMSNs results in the release of Fenton-like Mn2+ and Cu+ ions for •OH generation (CDT); simultaneously, the released Mn2+ ions couple with NIR-II luminescence imaging, computed tomography (CT) imaging, and magnetic resonance (MR) imaging of LDNPs, performing a TME-amplified trimodal effect. In such a nanomedicine, the TME modulation, bimetallic silicate photosensitizer, Fenton-like nanocatalyst, and NIR-II/MR/CT contrast agent were achieved "one for all", thereby realizing highly efficient tumor theranostics.
177 citations
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TL;DR: The multifunctional cancer therapy platform with multimode imaging effects realizes a true sense of light‐induced imaging‐guided cancer therapy.
Abstract: The NIR light-induced imaging-guided cancer therapy is a promising route in the targeting cancer therapy field. However, up to now, the existing single-modality light-induced imaging effects are not enough to meet the higher diagnosis requirement. Thus, the multifunctional cancer therapy platform with multimode light-induced imaging effects is highly desirable. In this work, captopril stabilized-Au nanoclusters Au25(Capt)18−(Au25) are assembled into the mesoporous silica shell coating outside of Nd3+-sensitized upconversion nanoparticles (UCNPs) for the first time. The newly formed Au25 shell exhibits considerable photothermal effects, bringing about the photothermal imaging and photoacoustic imaging properties, which couple with the upconversion luminescence imaging. More importantly, the three light-induced imaging effects can be simultaneously achieved by exciting with a single NIR light (808 nm), which is also the triggering factor for the photothermal and photodynamic cancer therapy. Besides, the nanoparticles can also present the magnetic resonance and computer tomography imaging effects due to the Gd3+ and Yb3+ ions in the UCNPs. Furthermore, due to the photodynamic and the photothermal effects, the nanoparticles possess efficient in vivo tumor growth inhibition under the single irradiation of 808 nm light. The multifunctional cancer therapy platform with multimode imaging effects realizes a true sense of light-induced imaging-guided cancer therapy.
177 citations
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TL;DR: In this paper, a symmetric outward convex corrugated tube design is introduced for parabolic trough receivers with the aim of increasing their heat transfer performance and reliability, and an optical-thermal-structural sequential coupled method is developed to analyze the heat transfer and thermal deformation of the glass cover and metal tube of the parabolic tube.
176 citations
Authors
Showing all 31363 results
Name | H-index | Papers | Citations |
---|---|---|---|
Peng Shi | 137 | 1371 | 65195 |
Lei Zhang | 130 | 2312 | 86950 |
Yang Liu | 129 | 2506 | 122380 |
Tao Zhang | 123 | 2772 | 83866 |
Wei Zhang | 104 | 2911 | 64923 |
Wei Liu | 102 | 2927 | 65228 |
Feng Yan | 101 | 1041 | 41556 |
Lianzhou Wang | 95 | 596 | 31438 |
Xiaodong Xu | 94 | 1122 | 50817 |
Zhiguo Yuan | 93 | 633 | 28645 |
Rong Wang | 90 | 950 | 32172 |
Jun Lin | 88 | 699 | 30426 |
Yufeng Zheng | 87 | 797 | 31425 |
Taihong Wang | 84 | 279 | 25945 |
Mao-Sheng Cao | 81 | 314 | 24046 |