Paul Sabatier University

About: Paul Sabatier University is a education organization based out in Toulouse, France. It is known for research contribution in the topics: Population & Catalysis. The organization has 15431 authors who have published 23386 publications receiving 858364 citations.

The global dust SED: tracing the nature and evolution of dust with DustEM

Abstract: The Planck and Herschel missions are currently measuring the far-infrared to millimeter emission of dust, which combined with existing IR data, will for the first time provide the full spectral energy distribution (SED) of the galactic interstellar medium dust emission, from the mid-IR to the mm range, with an unprecedented sensitivity and down to spatial scales ∼30 �� . Such a global SED will allow a systematic study of the dust evolution processes (e.g. grain growth or fragmentation) that directly affect the SED because they redistribute the dust mass among the observed grain sizes. The dust SED is also affected by variations of the radiation field intensity. Here we present a versatile numerical tool, DustEM, that predicts the emission and extinction of dust grains given their size distribution and their optical and thermal properties. In order to model dust evolution, DustEM has been designed to deal with a variety of grain types, structures and size distributions and to be able to easily include new dust physics. We use DustEM to model the dust SED and extinction in the diffuse interstellar medium at high-galactic latitude (DHGL), a natural reference SED that will allow us to study dust evolution. We present a coherent set of observations for the DHGL SED, which has been obtained by correlating the IR and HI-21 cm data. The dust components in our DHGL model are (i) polycyclic aromatic hydrocarbons; (ii) amorphous carbon and (iii) amorphous silicates. We use amorphous carbon dust, rather than graphite, because it better explains the observed high abundances of gas-phase carbon in shocked regions of the interstellar medium. Using the DustEM model, we illustrate how, in the optically thin limit, the IRAS/Planck HFI (and likewise Spitzer/Herschel for smaller spatial scales) photometric band ratios of the dust SED can disentangle the influence of the exciting radiation field intensity and constrain the abundance of small grains (a < 10 nm) relative to the larger grains. We also discuss the contributions of the different grain populations to the IRAS, Planck (and similarly to Herschel) channels. Such information is required to enable a study of the evolution of dust as well as to systematically extract the dust thermal emission from CMB data and to analyze the emission in the Planck polarized channels. The DustEM code described in this paper is publically available. Dust plays a key role in the physics (e.g. heating of the gas, coupling to the magnetic field) and chemistry (formation of H2, shielding of molecules from dissociative radiation) of the interstellar medium (ISM). Heated by stellar photons, dust grains radiate away the absorbed energy by emission in the near-IR to mm range. Dust emission can thus be used as a tracer of the radiation field intensity and, hence, of star formation activity. Assuming a constant dust abundance, the far-IR to mm dust emission is also used to derive the total column density along a line of sight and to provide mass estimates. The impact of dust on the ISM and the use of its emission as a tracer of the local conditions depends on the dust properties and abundances. It is therefore of major importance to understand dust properties and their evolution throughout the ISM. The instruments onboard the Herschel and Planck satel

Induction of Competence Regulons as a General Response to Stress in Gram-Positive Bacteria

Abstract: Bacterial transformation, a programmed mechanism for genetic exchange originally discovered in Streptococcus pneumoniae, is widespread in bacteria. It is based on the uptake and integration of exogenous DNA into the recipient genome. This review examines whether induction of competence for genetic transformation is a general response to stress in gram-positive bacteria. It compares data obtained with bacteria chosen for their different lifestyles, the soil-dweller Bacillus subtilis and the major human pathogen S. pneumoniae. The review focuses on the relationship between competence and other global responses in B. subtilis, as well as on recent evidence for competence induction in response to DNA damage or antibiotics and for the ability of S. pneumoniae to use competence as a substitute for SOS. This comparison reveals that the two species use different fitness-enhancing strategies in response to stress conditions. Whereas B. subtilis combines competence and SOS induction, S. pneumoniae relies only on competence to generate genetic diversity through transformation.

Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population.

Abstract: The distribution of risk factors for cardiovascular disease in patients aged 35-44 years who were treated for human immunodeficiency virus type 1 (HIV-1) infection was compared with that for a population-based cohort. HIV-1-infected men treated with a protease inhibitor-containing regimen (n=223), compared with HIV-1-uninfected men (n=527), were characterized by a lower prevalence of hypertension, a lower mean high-density lipoprotein cholesterol level, a higher prevalence of smoking, a higher mean waist-to-hip ratio, and a higher mean triglyceride level. No difference was found for total plasma or low-density cholesterol levels, nor for the prevalence of diabetes. Similar trends were observed among female subjects. The predicted risk of coronary heart disease was greater among HIV-1-infected men (relative risk [RR], 1.20) and women (RR, 1.59; P<10(-6) for both), compared with the HIV-1-uninfected cohort. The estimated attributable risks due to smoking were 65% and 29% for HIV-1-infected men and women, respectively. Because most HIV-1-infected people will ultimately need antiretroviral therapy, risk factors for cardiovascular disease should be determined at the initiation of treatment, and interventions should be considered for all patients who have them.

On Possibility/Probability Transformations

Abstract: The problem of converting possibility measures into probability measures has received attention in the past, but not by so many scholars. This question is philosophically interesting as part of the debate between probability and fuzzy sets. The imbedding of fuzzy sets into random set theory as done by Goodman and Nguyen (1985), Wang Peizhuang (1983), among others, has solved this question in principle. However the conversion problem has roots at least as much in the possibility/probability consistency principle of Zadeh (1978), that he proposed in the paper founding possibility theory.

Convergence of an improved CIPSI algorithm

Abstract: The configuration interaction CIPSI algorithm defines three classes of determinants of decreasing importance; the most important ones (∼ 100) are generators, the mean class (∼ 10 3 ) is treated variationally or to the fourth order, while the less important ones (∼ 10 5 ) are treated to the second order only. The accuracy of the result is studied as a function of the borders between the classes in the case of H 2 O (double-zeta basis set), where the exact solution is known, and for the nearly degenerate CN + problem.