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Institution

University of Grenoble

EducationSaint-Martin-d'Hères, France
About: University of Grenoble is a education organization based out in Saint-Martin-d'Hères, France. It is known for research contribution in the topics: Population & Context (language use). The organization has 25658 authors who have published 45143 publications receiving 909760 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, the spectral properties of PDS 70 b have been characterized using spectrophotometry of the entire near-infrared range (0.96-3.8 μ m).
Abstract: Context . The observation of planets in their formation stage is a crucial but very challenging step in understanding when, how, and where planets form. PDS 70 is a young pre-main sequence star surrounded by a transition disk, in the gap of which a planetary-mass companion has recently been discovered. This discovery represents the first robust direct detection of such a young planet, possibly still at the stage of formation.Aims . We aim to characterize the orbital and atmospheric properties of PDS 70 b, which was first identified on May 2015 in the course of the SHINE survey with SPHERE, the extreme adaptive-optics instrument at the VLT.Methods . We obtained new deep SPHERE/IRDIS imaging and SPHERE/IFS spectroscopic observations of PDS 70 b. The astrometric baseline now covers 6 yr, which allowed us to perform an orbital analysis. For the first time, we present spectrophotometry of the young planet which covers almost the entire near-infrared range (0.96–3.8 μ m). We use different atmospheric models covering a large parameter space in temperature, log g , chemical composition, and cloud properties to characterize the properties of the atmosphere of PDS 70 b.Results . PDS 70 b is most likely orbiting the star on a circular and disk coplanar orbit at ~22 au inside the gap of the disk. We find a range of models that can describe the spectrophotometric data reasonably well in the temperature range 1000–1600 K and log g no larger than 3.5 dex. The planet radius covers a relatively large range between 1.4 and 3.7 R J with the larger radii being higher than expected from planet evolution models for the age of the planet of 5.4 Myr.Conclusions . This study provides a comprehensive data set on the orbital motion of PDS 70 b, indicating a circular orbit and a motion coplanar with the disk. The first detailed spectral energy distribution of PDS 70 b indicates a temperature typical of young giant planets. The detailed atmospheric analysis indicates that a circumplanetary disk may contribute to the total planetflux.

192 citations

Journal ArticleDOI
13 Aug 2015
TL;DR: The current opportunities and challenges related to the exploitation of multimodal data for Earth observation are sketched by leveraging the outcomes of the data fusion contests, organized by the IEEE Geoscience and Remote Sensing Society since 2006.
Abstract: Remote sensing is one of the most common ways to extract relevant information about Earth and our environment. Remote sensing acquisitions can be done by both active (synthetic aperture radar, LiDAR) and passive (optical and thermal range, multispectral and hyperspectral) devices. According to the sensor, a variety of information about the Earth's surface can be obtained. The data acquired by these sensors can provide information about the structure (optical, synthetic aperture radar), elevation (LiDAR), and material content (multispectral and hyperspectral) of the objects in the image. Once considered together their complementarity can be helpful for characterizing land use (urban analysis, precision agriculture), damage detection (e.g., in natural disasters such as floods, hurricanes, earthquakes, oil spills in seas), and give insights to potential exploitation of resources (oil fields, minerals). In addition, repeated acquisitions of a scene at different times allows one to monitor natural resources and environmental variables (vegetation phenology, snow cover), anthropological effects (urban sprawl, deforestation), climate changes (desertification, coastal erosion), among others. In this paper, we sketch the current opportunities and challenges related to the exploitation of multimodal data for Earth observation. This is done by leveraging the outcomes of the data fusion contests, organized by the IEEE Geoscience and Remote Sensing Society since 2006. We will report on the outcomes of these contests, presenting the multimodal sets of data made available to the community each year, the targeted applications, and an analysis of the submitted methods and results: How was multimodality considered and integrated in the processing chain? What were the improvements/new opportunities offered by the fusion? What were the objectives to be addressed and the reported solutions? And from this, what will be the next challenges?

192 citations

Journal ArticleDOI
TL;DR: The origin of the electrical control of skyrmions stability is unveiled and it is shown that both magnetic dipolar interaction and the Dzyaloshinskii-Moriya interaction play an important role in theskyrmion bubble stabilization.
Abstract: Nanoscale magnetic skyrmions are considered as potential information carriers for future spintronics memory and logic devices. Such applications will require the control of their local creation and annihilation, which involves so far solutions that are either energy consuming or difficult to integrate. Here we demonstrate the control of skyrmion bubbles nucleation and annihilation using electric field gating, an easily integrable and potentially energetically efficient solution. We present a detailed stability diagram of the skyrmion bubbles in a Pt/Co/oxide trilayer and show that their stability can be controlled via an applied electric field. An analytical bubble model with the Dzyaloshinskii-Moriya interaction imbedded in the domain wall energy accounts for the observed electrical skyrmion switching effect. This allows us to unveil the origin of the electrical control of skyrmions stability and to show that both magnetic dipolar interaction and the Dzyaloshinskii-Moriya interaction play an important ro...

192 citations

Journal ArticleDOI
TL;DR: In this paper, a simple model is developed to describe the process of load transfer and crack initiation in the particles, which does not take into account particle interactions and the role of clustering.
Abstract: The process of damage by particle cracking has been followed in a composite of A356 Al containing 20% by volume SiC. The probability of particle cracking is influenced by both particle size and aspect ratio and the results indicate that the relative importance of these factors depends on the Weibull modulus of the SiC particles. A simple model is developed to describe the process of load transfer and crack initiation in the particles. This initial model does not take into account particle interactions and the role of clustering but does provide an initial fragment to describe the damage initiation process.

192 citations

Journal ArticleDOI
01 Jan 2021-Nature
TL;DR: Using mouse models of skin squamous cell carcinoma and lung tumours, it is found that deletion of Fat1 accelerates tumour initiation and malignant progression and promotes a hybrid epithelial-to-mesenchymal transition (EMT) phenotype.
Abstract: FAT1, which encodes a protocadherin, is one of the most frequently mutated genes in human cancers1-5. However, the role and the molecular mechanisms by which FAT1 mutations control tumour initiation and progression are poorly understood. Here, using mouse models of skin squamous cell carcinoma and lung tumours, we found that deletion of Fat1 accelerates tumour initiation and malignant progression and promotes a hybrid epithelial-to-mesenchymal transition (EMT) phenotype. We also found this hybrid EMT state in FAT1-mutated human squamous cell carcinomas. Skin squamous cell carcinomas in which Fat1 was deleted presented increased tumour stemness and spontaneous metastasis. We performed transcriptional and chromatin profiling combined with proteomic analyses and mechanistic studies, which revealed that loss of function of FAT1 activates a CAMK2-CD44-SRC axis that promotes YAP1 nuclear translocation and ZEB1 expression that stimulates the mesenchymal state. This loss of function also inactivates EZH2, promoting SOX2 expression, which sustains the epithelial state. Our comprehensive analysis identified drug resistance and vulnerabilities in FAT1-deficient tumours, which have important implications for cancer therapy. Our studies reveal that, in mouse and human squamous cell carcinoma, loss of function of FAT1 promotes tumour initiation, progression, invasiveness, stemness and metastasis through the induction of a hybrid EMT state.

191 citations


Authors

Showing all 25961 results

NameH-indexPapersCitations
Dieter Lutz13967167414
Marcella Bona137139192162
Nicolas Berger137158196529
Cordelia Schmid135464103925
J. F. Macías-Pérez13448694715
Marina Cobal132107885437
Lydia Roos132128489435
Tetiana Hryn'ova131105984260
Johann Collot131101882865
Remi Lafaye131101283281
Jan Stark131118687025
Sabine Crépé-Renaudin129114282741
Isabelle Wingerter-Seez12993079689
James Alexander12988675096
Jessica Levêque129100670208
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023166
2022698
20215,127
20205,328
20195,192
20184,999