Institution
University of Rennes
Education•Rennes, France•
About: University of Rennes is a education organization based out in Rennes, France. It is known for research contribution in the topics: Population & Catalysis. The organization has 18404 authors who have published 40374 publications receiving 995327 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: The nested RT-PCR technique identified the presence of transcript encoding ERalpha mRNA in human skeletal muscles and revealed gender difference in deltoid muscle from men and women.
Abstract: Introduction/purpose To explain the effect of estrogen on skeletal muscle, the presence of estrogen receptor alpha mRNA (ERalpha mRNA) was investigated in human skeletal muscle. Methods The highly sensitive technique of nested reverse transcriptase-polymerase chain reaction (nested RT-PCR) was applied on a variety of tissue samples of both sexes: women (deltoid, pectoral, and uterus muscles) (N= 3) and men (deltoid muscle) (N= 3). The total ribonucleic acid was isolated from each tissue sample, reverse transcribed in a thermocycler, and nested PCR was then performed with specific primers. The by-products were analyzed by agarose gel electrophoresis. Internal standard 28S was simultaneously amplified. The ERalpha mRNA level was quantitated by using the ERalpha mRNA/28S mRNA ratio. Results The expected 204-bp product corresponding to ERalpha was amplified in all tested tissue samples, i.e., deltoid, pectoral, and uterine muscles from women and deltoid muscle from men. The ERalpha mRNA/28S mRNA ratios indicating the receptor expression levels in deltoid muscle from men and women were 0.945 +/- 0.393 (mean +/- SD) (N= 3) and 0.973 +/- 0.136 (mean +/- SD) (N= 2), respectively. Conclusions In conclusion, the nested RT-PCR technique identified the presence of transcript encoding ERalpha mRNA in human skeletal muscles. Semi-quantification did not reveal gender difference.
191 citations
••
TL;DR: The controlled growth of hybrid perovskites on nickel oxide (NiO) is shown, resulting in the formation of thin films with enhanced crystallinity with characteristic peak width and splitting reminiscent of the tetragonal phase in single crystals, elucidate the critical role of the quality of thePerovskite/hole transport layer interface in rendering high-performance and photostable optoelectronic devices.
Abstract: Hybrid perovskites are on a trajectory toward realizing the most efficient single-junction, solution-processed photovoltaic devices. However, a critical issue is the limited understanding of the correlation between the degree of crystallinity and the emergent perovskite/hole (or electron) transport layer on device performance and photostability. Here, the controlled growth of hybrid perovskites on nickel oxide (NiO) is shown, resulting in the formation of thin films with enhanced crystallinity with characteristic peak width and splitting reminiscent of the tetragonal phase in single crystals. Photophysical and interface sensitive measurements reveal a reduced trap density at the perovskite/NiO interface in comparison with perovskites grown on poly(3,4-ethylene dioxy thiophene) polystyrene sulfonate. Photovoltaic cells exhibit a high open circuit voltage (1.12 V), indicating a near-ideal energy band alignment. Moreover, photostability of photovoltaic devices up to 10-Suns is observed, which is a direct result of the superior crystallinity of perovskite thin films on NiO. These results elucidate the critical role of the quality of the perovskite/hole transport layer interface in rendering high-performance and photostable optoelectronic devices.
191 citations
••
University of California, Davis1, University of Texas Southwestern Medical Center2, University of Texas MD Anderson Cancer Center3, Université de Montréal4, University of Vienna5, Heidelberg University6, Vita-Salute San Raffaele University7, University of Michigan8, Medical University of Graz9, University of Rennes10, Cornell University11, Keio University12, Clínica Alemana13
TL;DR: Adjuvant chemotherapy is infrequently used to treat high risk upper tract urothelial carcinoma after nephroureterectomy and it appears that adjuvant chemotherapy confers minimal impact on overall or cancer specific survival in this group.
191 citations
••
TL;DR: Second-harmonic generation is capable of imaging up to ∼400 μm deep into intact tissue with submicron resolution and little out-of-focus photodamage or bleaching, its ability to record fast electrical activity should prove valuable to future electrophysiology studies.
Abstract: Nonlinear microscopy has proven to be essential for neuroscience investigations of thick tissue preparations. However, the optical recording of fast (∼1 msec) cellular electrical activity has never until now been successfully combined with this imaging modality. Through the use of second-harmonic generation microscopy of primary Aplysia neurons in culture labeled with 4-[4-(dihexylamino)phenyl][ethynyl]-1-(4-sulfobutyl)pyridinium (inner salt), we optically recorded action potentials with 0.833 msec temporal and 0.6 μm spatial resolution on soma and neurite membranes. Second-harmonic generation response as a function of change in membrane potential was found to be linear with a signal change of ∼6%/100 mV. The signal-to-noise ratio was ∼1 for single-trace action potential recordings but was readily increased to ∼6–7 with temporal averaging of ∼50 scans. Photodamage was determined to be negligible by observing action potential characteristics, cellular resting potential, and gross cellular morphology during and after laser illumination. High-resolution (micrometer scale) optical recording of membrane potential activity by previous techniques has been limited to imaging depths an order of magnitude less than nonlinear methods. Because second-harmonic generation is capable of imaging up to ∼400 μm deep into intact tissue with submicron resolution and little out-of-focus photodamage or bleaching, its ability to record fast electrical activity should prove valuable to future electrophysiology studies.
191 citations
••
TL;DR: In this article, a detailed catalogue of bedding-parallel fibrous veins of fibrous minerals is presented, where the fibres are mutually parallel and have formed quasi-vertically.
190 citations
Authors
Showing all 18470 results
Name | H-index | Papers | Citations |
---|---|---|---|
Philippe Froguel | 166 | 820 | 118816 |
Bart Staels | 152 | 824 | 86638 |
Yi Yang | 143 | 2456 | 92268 |
Geoffrey Burnstock | 141 | 1488 | 99525 |
Shahrokh F. Shariat | 118 | 1637 | 58900 |
Lutz Ackermann | 116 | 669 | 45066 |
Douglas R. MacFarlane | 110 | 864 | 54236 |
Elliott H. Lieb | 107 | 512 | 57920 |
Fu-Yuan Wu | 107 | 367 | 42039 |
Didier Sornette | 104 | 1295 | 44157 |
Stefan Hild | 103 | 452 | 68228 |
Pierre I. Karakiewicz | 101 | 1207 | 40072 |
Philippe Dubois | 101 | 1098 | 48086 |
François Bondu | 100 | 440 | 69284 |
Jean-Michel Savéant | 98 | 517 | 33518 |