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Institution

University of Rennes

EducationRennes, France
About: University of Rennes is a education organization based out in Rennes, France. It is known for research contribution in the topics: Population & Catalysis. The organization has 18404 authors who have published 40374 publications receiving 995327 citations.


Papers
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Journal ArticleDOI
02 Oct 2009-Science
TL;DR: Genome-wide association studies of more than 1000 dogs from 80 domestic breeds identified distinct mutations in three genes, RSPO2, FGF5, and KRT71 (encoding R-spondin–2, fibroblast growth factor– 5, and keratin-71, respectively), that together account for most coat phenotypes in purebred dogs in the United States.
Abstract: Coat color and type are essential characteristics of domestic dog breeds. Although the genetic basis of coat color has been well characterized, relatively little is known about the genes influencing coat growth pattern, length, and curl. We performed genome-wide association studies of more than 1000 dogs from 80 domestic breeds to identify genes associated with canine fur phenotypes. Taking advantage of both inter- and intrabreed variability, we identified distinct mutations in three genes, RSPO2, FGF5, and KRT71 (encoding R-spondin–2, fibroblast growth factor–5, and keratin-71, respectively), that together account for most coat phenotypes in purebred dogs in the United States. Thus, an array of varied and seemingly complex phenotypes can be reduced to the combinatorial effects of only a few genes.

304 citations

Journal ArticleDOI
TL;DR: In this paper, the Suzuki-Miyaura cross-couplings of organoboronic acids or organotrifluoroborates with aryl and alkenyl halides or triflates have become classic methods for generating carbon-carbon bonds.

304 citations

Journal ArticleDOI
TL;DR: A critical appraisal on the existing evidence for the role of LA metrics in evaluation of LVDD and consequent heart failure with preserved ejection fraction is provided.

304 citations

Journal ArticleDOI
01 Mar 1995-Nature
TL;DR: In this paper, the authors show that the choice of ligand can further increase the optical nonlinearity of ruthenium complexes to values in excess of 10-27e.s.u.
Abstract: OPTICALLY nonlinear organic materials show considerable potential for applications in optical signal processing and telecommunications1,2. Most materials are based on the p-nitro-aniline template, in which the optical nonlinearities are intimately associated with quasi-one-dimensional charge transfer. But there are problems associated with this conventional approach, arising from the strongly dipolar nature of the molecules2. It has recently been recognized3–5 that two- and three-dimensional stereochemistry offers new possibilities for the design and synthesis of optically nonlinear molecules, in which charge transfer is multidirectional rather than dipolar in character; octupolar nonlinearities have now been demonstrated in several molecular systems5–7. Tri-substituted ruthenium complexes6 appear particularly attractive because intense, multidirectional metal-to-ligand charge transfer leads to a significant enhancement of the optical nonlinearity, as quantified by the quadratic hyperpolarizability, β. Here we show that the choice of ligand can further increase β to values in excess of 10-27e.s.u., comparable to the best dipolar optically nonlinear molecules.

302 citations

Journal ArticleDOI
TL;DR: An evidence-based assessment demonstrates which parts of Antarctica are at growing risk from alien species that may become invasive and provides the means to mitigate this threat now and into the future as the continent's climate changes.
Abstract: Invasive alien species are among the primary causes of biodiversity change globally, with the risks thereof broadly understood for most regions of the world. They are similarly thought to be among the most significant conservation threats to Antarctica, especially as climate change proceeds in the region. However, no comprehensive, continent-wide evaluation of the risks to Antarctica posed by such species has been undertaken. Here we do so by sampling, identifying, and mapping the vascular plant propagules carried by all categories of visitors to Antarctica during the International Polar Year's first season (2007–2008) and assessing propagule establishment likelihood based on their identity and origins and on spatial variation in Antarctica's climate. For an evaluation of the situation in 2100, we use modeled climates based on the Intergovernmental Panel on Climate Change's Special Report on Emissions Scenarios Scenario A1B [Nakicenovic N, Swart R, eds (2000) Special Report on Emissions Scenarios: A Special Report of Working Group III of the Intergovernmental Panel on Climate Change (Cambridge University Press, Cambridge, UK)]. Visitors carrying seeds average 9.5 seeds per person, although as vectors, scientists carry greater propagule loads than tourists. Annual tourist numbers (∼33,054) are higher than those of scientists (∼7,085), thus tempering these differences in propagule load. Alien species establishment is currently most likely for the Western Antarctic Peninsula. Recent founder populations of several alien species in this area corroborate these findings. With climate change, risks will grow in the Antarctic Peninsula, Ross Sea, and East Antarctic coastal regions. Our evidence-based assessment demonstrates which parts of Antarctica are at growing risk from alien species that may become invasive and provides the means to mitigate this threat now and into the future as the continent's climate changes.

302 citations


Authors

Showing all 18470 results

NameH-indexPapersCitations
Philippe Froguel166820118816
Bart Staels15282486638
Yi Yang143245692268
Geoffrey Burnstock141148899525
Shahrokh F. Shariat118163758900
Lutz Ackermann11666945066
Douglas R. MacFarlane11086454236
Elliott H. Lieb10751257920
Fu-Yuan Wu10736742039
Didier Sornette104129544157
Stefan Hild10345268228
Pierre I. Karakiewicz101120740072
Philippe Dubois101109848086
François Bondu10044069284
Jean-Michel Savéant9851733518
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202321
2022176
20212,655
20202,735
20192,670
20182,378