University of Virginia

About: University of Virginia is a education organization based out in Charlottesville, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52543 authors who have published 113268 publications receiving 5220506 citations. The organization is also known as: U of V & UVa.

Two-year outcomes of surgical treatment of severe ischemic mitral regurgitation

Abstract: BackgroundIn a trial comparing coronary-artery bypass grafting (CABG) alone with CABG plus mitral-valve repair in patients with moderate ischemic mitral regurgitation, we found no significant difference in the left ventricular end-systolic volume index (LVESVI) or survival after 1 year. Concomitant mitral-valve repair was associated with a reduced prevalence of moderate or severe mitral regurgitation, but patients had more adverse events. We now report 2-year outcomes. MethodsWe randomly assigned 301 patients to undergo either CABG alone or the combined procedure. Patients were followed for 2 years for clinical and echocardiographic outcomes. ResultsAt 2 years, the mean (±SD) LVESVI was 41.2±20.0 ml per square meter of body-surface area in the CABG-alone group and 43.2±20.6 ml per square meter in the combined-procedure group (mean improvement over baseline, −14.1 ml per square meter and −14.6 ml per square meter, respectively). The rate of death was 10.6% in the CABG-alone group and 10.0% in the combined-...

Wind from a starburst galaxy nucleus

Abstract: Galaxies with highly active star formation regions (starburst galaxies) are inferred to have high supernova rates in the region of activity1,2 If most of the supernova energy input is thermalized, a strong wind is driven out of the active region The wind is probably so fast that gravitational forces are not involved We present here an analytical solution for the wind which is driven from a region of uniform mass and energy deposition The solution is applied to M82—the best observed case of a starbust galaxy The model can be directly compared with the gas pressure in M82 and with a wind velocity deduced from radio spectra The galaxy does have clouds orbiting out of the disk The interaction of the wind with the clouds can give rise to streaming motions and to X-ray emission The wind is expected to create a hole in any diffuse gas in which the galaxy is embedded The wind may have a significant role in the evolution of a starburst galaxy in that it transfers gas, which is probably heavy-element enriched, from the central regions to the outer parts of the galaxy

The Use of Foreign Currency Derivatives and Firm Market Value

Abstract: This article examines the use of foreign currency derivatives (FCDs) in a sample of 720 large U.S. nonfinancial firms between 1990and 1995 and its potential impact on firm value. Using Tobin’s Q as a proxy for firm value, we find a positive relation between firm value and the use of FCDs. The hedging premium is statistically and economically significant for firms with exposure to exchange rates and is on average 4.87% of firm value. We also find some evidence consistent with the hypothesis that hedging causes an increase in firm value.