Journal ArticleDOI
Pharmaceutical Applications of Polymorphism
John K. Haleblian,Walter McCrone +1 more
TLDR
Polymorphism is the ability of any element or compound to crystallize as more than one distinct crystal species (e.g., carbon as cubic diamond or hexagonal graphite).About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1969-08-01. It has received 894 citations till now. The article focuses on the topics: Polymorphism (materials science) & Crystal.read more
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Patent
Crystalline Polymorph of Doxazosin Mesylate (Form IV) and Process for Preparation Thereof
Rajendra Narayanrao Kankan,Dharmaraj Ramachandra Rao,Manish Gopaldas Gangrade,Shrikant Suresh Mudgal +3 more
TL;DR: In this article, a process for the preparation and use of doxazosin mesylate is described. But this process is restricted to the Crystalline Form (IV) of DOXASO.
Journal ArticleDOI
Polymorphic Behavior of Two Organic Zwitterions: Two Rare Cases of No Observable Conversion between Polymorphs
TL;DR: In this article, the solid-state behavior of two organic zwitterions, (Z)-3-carboxy-2-(4-cyanopyridin-1-ium-1yl)-acrylate (1), has been extensively investigated.
Journal ArticleDOI
A New Approach for Enhancing the Dissolution Rate of Phenacetin
TL;DR: In this paper, a new approach for enhancing the intrinsic dissolution rate of phenacetin is ascribed, which is based on the concept of the recrystallization of phencetin from different surfactants concentrations.
Journal ArticleDOI
Influence of selected water soluble carbohydrates on the dissolution profile of prednisolone
Salah U. Ahmed,Parshotam Madan +1 more
TL;DR: In this paper, the utilization of three water soluble carbohydrates as carrier to improve the dissolution rate of prednisolone was studied and their dissolution profile was compared with the dissolution profile of the pure drug.
Journal ArticleDOI
Studies of the mechanism of crystal growth of hexamethylmelamine II. Rates of growth of the crystal faces
Hak-Kim Chan,Igor Gonda +1 more
TL;DR: In this article, the growth rate of a single crystal of HMM was studied in solution of methanol and cyclohexane and the relationship between the crystal size (length and breadth) and time ( t ) was best described using √ t as the independent variable and fitting the dependence by second or third degree polynomial equations.
References
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Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.
Journal ArticleDOI
The united states pharmacopeia.
TL;DR: The Pharmacopeia was called into being by physicians in 1820, and in 1850 pharmacists were admitted to the convention; since then physicians have gradually relinquished control to pharmacists, and to-day the authors are confronted with an anomalous condition.
Book
Thermal methods of analysis
TL;DR: In this article, a revised edition necessitated by the phenomenal growth of the field during the past decade contains 90% new material, focusing on tech niques and applications of thermal analysis.