Journal ArticleDOI
Pharmaceutical Applications of Polymorphism
John K. Haleblian,Walter McCrone +1 more
TLDR
Polymorphism is the ability of any element or compound to crystallize as more than one distinct crystal species (e.g., carbon as cubic diamond or hexagonal graphite).About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1969-08-01. It has received 894 citations till now. The article focuses on the topics: Polymorphism (materials science) & Crystal.read more
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Patent
Solid salt forms of a pyrrole substituted 2-indolinone
TL;DR: In this article, solid salt forms of the 3-pyrrole substituted 2-indolinone compound 5-[5-fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-Pyrrole-3-carboxylic acid (2-pirrolidin-1-yl-ethyl)-amide.
Book ChapterDOI
Polymorphism and Supramolecular Isomerism: The Impasse of Coordination Polymers
TL;DR: In this article, a narrow link between chemistry and crystallography has been outlined, which has led to the identification of polymorphism and provided a priceless grounding to understand structure-properties relationship.
Journal ArticleDOI
Novel solid forms of insomnia drug suvorexant with improved solubility and dissolution: accessing salts from a salt solvate route
Suman Gundlapalli,Ramesh Devarapalli,Ramesh Reddy Mudda,Ramanaiah Chennuru,Ravichandrababu Rupakula +4 more
TL;DR: Suvorexant (SRX) is a dual orexin receptor antagonist used for the treatment of insomnia.
Crystallization as a Tool for Controlling and Designing Properties of Pharmaceutical Solids
TL;DR: In this paper, the authors present a list of original publications and abstractions of the following topics: ABBREVIATIONS and ACRONYMS, ABBEVIATION, and ANONYMOUS.
References
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Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.
Journal ArticleDOI
The united states pharmacopeia.
TL;DR: The Pharmacopeia was called into being by physicians in 1820, and in 1850 pharmacists were admitted to the convention; since then physicians have gradually relinquished control to pharmacists, and to-day the authors are confronted with an anomalous condition.
Book
Thermal methods of analysis
TL;DR: In this article, a revised edition necessitated by the phenomenal growth of the field during the past decade contains 90% new material, focusing on tech niques and applications of thermal analysis.