Journal ArticleDOI
Pharmaceutical Applications of Polymorphism
John K. Haleblian,Walter McCrone +1 more
TLDR
Polymorphism is the ability of any element or compound to crystallize as more than one distinct crystal species (e.g., carbon as cubic diamond or hexagonal graphite).About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1969-08-01. It has received 894 citations till now. The article focuses on the topics: Polymorphism (materials science) & Crystal.read more
Citations
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Journal ArticleDOI
The solid state of pharmaceuticals
TL;DR: The solid state of pharmaceuticals is discussed in this CrystEngComm themed issue entitled “The solid State of Pharmaceuticals.”
Book ChapterDOI
Use of Apparatus 4 in Dissolution Testing, Including Sparingly and Poorly Soluble Drugs
Journal ArticleDOI
Effect of laser irradiation on the stability of a photo-sensitive active pharmaceutical ingredient by Raman microscopy
TL;DR: The results suggest that the non-confocal laser Raman microscopy will be a useful technique for the measuring of Raman spectra of photo-sensitive materials with a long-term exposure.
Journal ArticleDOI
Polymorphs, Solvatomorphs, Hydrate, and Perhydrate of Dabrafenib
TL;DR: In this paper , the anticancer drug dabrafenib (DBF) was performed using a wide range of non-polar aprotic, polar aproic, and polar protic solvents.
Journal ArticleDOI
Crystal Form of A Camptothecin Derivative
Young-Taek Sohn,Hyun-Young Moon +1 more
TL;DR: In this article, three polymorphic modifications of CKD-602, water soluble derivative of camptothecin, were obtained by recrystallization from different organic solvents and characterized by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and X-ray powder diffraction (XRPD).
References
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Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.
Journal ArticleDOI
The united states pharmacopeia.
TL;DR: The Pharmacopeia was called into being by physicians in 1820, and in 1850 pharmacists were admitted to the convention; since then physicians have gradually relinquished control to pharmacists, and to-day the authors are confronted with an anomalous condition.
Book
Thermal methods of analysis
TL;DR: In this article, a revised edition necessitated by the phenomenal growth of the field during the past decade contains 90% new material, focusing on tech niques and applications of thermal analysis.