Journal ArticleDOI
Pharmaceutical Applications of Polymorphism
John K. Haleblian,Walter McCrone +1 more
TLDR
Polymorphism is the ability of any element or compound to crystallize as more than one distinct crystal species (e.g., carbon as cubic diamond or hexagonal graphite).About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1969-08-01. It has received 894 citations till now. The article focuses on the topics: Polymorphism (materials science) & Crystal.read more
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Reference EntryDOI
The Cambridge Structural Database System and Its Applications in Supramolecular Chemistry and Materials Design
Elna Pidcock,James A. Chisholm,Peter A. Wood,Peter T. A. Galek,László Fábián,Oliver Korb,Aurora J. Cruz-Cabeza,John W. Liebeschuetz,Colin R. Groom,Frank H. Allen +9 more
TL;DR: The Cambridge Structural Database (CSD) as discussed by the authors contains more than half a million small-molecule organic and metal-organic crystal structures, including motif topology searches and crystal packing feature searches, as well as evaluating crystal packing similarity and H-bond propensity analysis.
Journal ArticleDOI
Solid State of Tulobuterol : Characterization, Dissolution, Transformation
Eui-Seon Do,Young-Taek Sohn +1 more
TL;DR: In this article, the authors investigated the existence of new crystal forms of tulobuterol which are used to prevent morning asthma attacks by agonist and the transformation of crystal forms, and they showed significant differences in the dissolution rate.
Journal ArticleDOI
Pharmaceutical Polymorphism Studies by Infrared Spectroscopic Imaging
TL;DR: In this article, a variety of pharmaceutical polycrystalline films using infrared (IR) spectroscopic imaging was investigated using a conventional FT-IR microscope with visible polarized light capabilities.
Dissertation
Characterisation of organic solids using solid-state NMR spectroscopy
TL;DR: In this article, a scoring function for evaluating crystal structures of tolfenamic acid (TFA) using solution-and solid-state NMR data is proposed to discriminate four similar TFA polymorphs.
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Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.
Journal ArticleDOI
The united states pharmacopeia.
TL;DR: The Pharmacopeia was called into being by physicians in 1820, and in 1850 pharmacists were admitted to the convention; since then physicians have gradually relinquished control to pharmacists, and to-day the authors are confronted with an anomalous condition.
Book
Thermal methods of analysis
TL;DR: In this article, a revised edition necessitated by the phenomenal growth of the field during the past decade contains 90% new material, focusing on tech niques and applications of thermal analysis.