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Open AccessJournal ArticleDOI

Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli.

Mariela M. Marani, +21 more
- 20 Mar 2017 - 
- Vol. 605, pp 70-80
TLDR
Patagonia's biodiversity has been explored from many points of view, however, skin secretions of native amphibians have not been evaluated for antimicrobial peptide research until now and the first peptides described for amphibians of the Pleurodema genus are described.
About: 
This article is published in Gene.The article was published on 2017-03-20 and is currently open access. It has received 21 citations till now. The article focuses on the topics: Antimicrobial peptides & Pleurodema.

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Citations
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Journal ArticleDOI

Exploring Molecular-Biomembrane Interactions with Surface Plasmon Resonance and Dual Polarization Interferometry Technology: Expanding the Spotlight onto Biomembrane Structure

Tzong-Hsien Lee, +4 more
- 25 May 2018 - 
TL;DR: A review of the application of surface plasmon resonance and dual polarization interferometry-based biosensors to the study of biomembrane-based systems using both planar mono- or bilayers or liposomes is presented.
Journal ArticleDOI

Synergistic and antibiofilm properties of ocellatin peptides against multidrug-resistant Pseudomonas aeruginosa.

Lucinda J. Bessa, +10 more
- 08 Jan 2018 - 
TL;DR: Ocellatin-PT3 may be promising as a template for the development of novel antimicrobial peptides against P. aeruginosa, and was capable of preventing the proliferation of 48-h mature biofilms at concentrations ranging from 4 to 8× the MIC.
Journal ArticleDOI

Biological properties of chitosan derivatives associated with the ceftazidime drug.

L. A. Pereira, +5 more
- 15 Oct 2019 - 
TL;DR: The biocompatibility of the derivatives was confirmed by the low hemolytic rate (<5%), non-toxic on Artemia salina (LD50%>3000 ppm), and significant index (1-34%) of antioxidant activity, and the results demonstrated that chitosan and its derivatives are promising biomaterials.
Journal ArticleDOI

An Atlas of Anionic Antimicrobial Peptides from Amphibians.

Sarah R. Dennison, +3 more
- 25 Dec 2018 - 
TL;DR: It is concluded that amphibian AAMPs represent an untapped potential source of biologically active agents and merit far greater research interest.
Journal ArticleDOI

Bioinspired Designs, Molecular Premise and Tools for Evaluating the Ecological Importance of Antimicrobial Peptides

Elvis Legala Ongey, +2 more
- 10 Jul 2018 - 
TL;DR: An overview of recent developments in antimicrobial peptides (AMPs), summarizing structural diversity, potential new applications, activity targets and microbial killing responses in general is provided.
References
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Journal ArticleDOI

Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction.

Yimin Shen, +8 more
- 14 Oct 2014 - 
TL;DR: The results indicate that if the coarse-grained PEP-FOLD2 method is approaching maturity, the authors are not at the end of the game of mini-protein structure prediction, but this opens new perspectives for large-scale in silico experiments.
Journal ArticleDOI

PEP-FOLD: an online resource for de novo peptide structure prediction

Julien Maupetit, +2 more
- 01 Jul 2009 - 
TL;DR: PEP-FOLD, an online service, aimed at de novo modelling of 3D conformations for peptides between 9 and 25 amino acids in aqueous solution, finds that it locates lowest energy conformations differing by 2.6 Å Cα root mean square deviation from the full NMR structures.
Journal ArticleDOI

Atomic force microscopy study of the antibacterial effects of chitosans on Escherichia coli and Staphylococcus aureus.

Peter Eaton, +5 more
- 01 Sep 2008 - 
TL;DR: The nanoindentation results suggested that despite little modification observed in the Gram-positive bacteria in morphological studies, cell wall damage had indeed occurred, since cell wall stiffness was reduced after chitooligosaccharide treatment.
Journal ArticleDOI

Antimicrobial peptides and wound healing: biological and therapeutic considerations

Maria Luisa Mangoni, +2 more
- 01 Mar 2016 - 
TL;DR: The evidence for a role of AMPs as endogenous mediators of wound healing and their promising therapeutic potential for the treatment of non‐life‐threatening skin and other epithelial injuries is provided.
Journal ArticleDOI

Anionic Antimicrobial Peptides from Eukaryotic Organisms

Frederick Harris, +2 more
- 30 Nov 2009 - 
TL;DR: An overview on current research into AAMPs is presented, which suggests that these peptides are an untapped source of putative antimicrobial agents with novel mechanisms of action and possess potential for application in the medical and biotechnological arenas.
Related Papers (5)

Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus.

Mariela M. Marani, +15 more
- 24 Jun 2015 - 

The NMR-derived solution structure of a new cationic antimicrobial peptide from the skin secretion of the anuran Hyla punctata.

Maura V. Prates, +10 more
- 26 Mar 2004 - 

Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

Mohamed F. Ali, +3 more
- 26 Nov 2001 - 

Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.

Cesar Vicente Ferreira Batista, +9 more
- 01 Aug 1999 - 

Length Effects in Antimicrobial Peptides of the (RW)n Series

Zhigang Liu, +6 more
- 01 Feb 2007 - 
Frequently Asked Questions (2)
Q1. What contributions have the authors mentioned in the paper "Thaulin-1: the first antimicrobial peptide isolated from the skin of a patagonian frog pleurodema thaul (anura: leptodactylidae: leiuperinae) with activity against escherichia coli" ?

Please cite this article as: Mariela M. Marani, Luis O. Perez, Alyne Rodrigues de Araujo, Alexandra Plácido, Carla F. Sousa, Patrick Veras Quelemes, Mayara Oliveira, Ana G. Gomes-Alves, Mariana Pueta, Paula Gameiro, Ana M. Tomás, Cristina Delerue-Matos, Peter Eaton, Silvia A. Camperi, Néstor G. Basso, Jose Roberto de Souza de Almeida Leite, Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul ( Anura: Leptodactylidae: Leiuperinae ) with activity against Escherichia coli. The address for the corresponding author was captured as affiliation for all authors. 

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