The Human Connectome: A Structural Description of the Human Brain
TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
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A cross-disorder connectome landscape of brain dysconnectivity
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Diffusion Tensor Tractography Reveals Disrupted Topological Efficiency in White Matter Structural Networks in Multiple Sclerosis
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The structural–functional connectome and the default mode network of the human brain
TL;DR: The data suggests that the DMN is the functional brain network, which uses the most direct structural connections, which seems to shape its functional repertoire and the computation of the whole-brain functional-structural connectome appears to be a valuable method to characterize global brain connectivity within and between populations.
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High-accuracy neurite reconstruction for high-throughput neuroanatomy
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