The Human Connectome: A Structural Description of the Human Brain
Reads0
Chats0
TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
More filters
Journal ArticleDOI
A Major Human White Matter Pathway Between Dorsal and Ventral Visual Cortex
Hiromasa Takemura,Ariel Rokem,Jonathan Winawer,Jason D. Yeatman,Jason D. Yeatman,Brian A. Wandell,Franco Pestilli,Franco Pestilli +7 more
TL;DR: This work combined fMRI, diffusion MRI, and fiber tractography to identify a major white matter pathway, the vertical occipital fasciculus (VOF), connecting maps within the dorsal and ventral visual cortex.
Journal ArticleDOI
From Cajal to Connectome and Beyond.
TL;DR: One goal of systems neuroscience is a structure-function model of nervous system organization that would allow mechanistic linking of mind, brain, and behavior.
Journal ArticleDOI
Fast approximate quadratic programming for graph matching.
Joshua T. Vogelstein,John M. Conroy,Vince Lyzinski,Louis J. Podrazik,Steven G. Kratzer,Eric T. Harley,Donniell E. Fishkind,R. Jacob Vogelstein,Carey E. Priebe +8 more
TL;DR: This work presents its graph matching algorithm, the Fast Approximate Quadratic assignment algorithm, and empirically demonstrates that the algorithm is faster and achieves a lower objective value on over 80% of the QAPLIB benchmark library, compared with the previous state-of-the-art.
Journal ArticleDOI
Combining complex networks and data mining: Why and how
Massimiliano Zanin,David Papo,Pedro Sousa,Ernestina Menasalvas,Andrea Nicchi,Elaine Kubik,Stefano Boccaletti +6 more
TL;DR: The starting point of this review is that these two fields can in fact advantageously be used in a synergistic manner, and that this state of affairs should be put down to contingent rather than conceptual differences.
Journal ArticleDOI
Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation
Claudia Alia,Cristina Spalletti,Stefano Lai,Alessandro Panarese,Giuseppe Lamola,Federica Bertolucci,Fabio Vallone,Fabio Vallone,Fabio Vallone,Angelo Di Garbo,Carmelo Chisari,Silvestro Micera,Silvestro Micera,Matteo Caleo +13 more
TL;DR: Advances in the comprehension of post-stroke network reorganization in patients and animal models are discussed, and the potential use of non-invasive brain stimulation techniques to boost recovery is illustrated.
References
More filters
Journal ArticleDOI
Distributed Hierarchical Processing in the Primate Cerebral Cortex
TL;DR: A summary of the layout of cortical areas associated with vision and with other modalities, a computerized database for storing and representing large amounts of information on connectivity patterns, and the application of these data to the analysis of hierarchical organization of the cerebral cortex are reported on.
Journal ArticleDOI
Sequence the Human Genome
TL;DR: This book aims to provide a history of Chinese modern art from 17th Century to the present day through the lens of 20th Century critics, practitioners, journalists, and mediaeval and modern-day critics.
Journal ArticleDOI
Dynamic causal modelling.
TL;DR: As with previous analyses of effective connectivity, the focus is on experimentally induced changes in coupling, but unlike previous approaches in neuroimaging, the causal model ascribes responses to designed deterministic inputs, as opposed to treating inputs as unknown and stochastic.
Journal ArticleDOI
Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging
Timothy E.J. Behrens,Heidi Johansen-Berg,Mark W. Woolrich,Mark W. Woolrich,Stephen M. Smith,Claudia A. M. Wheeler-Kingshott,P A Boulby,Gareth J. Barker,E L Sillery,K Sheehan,Olga Ciccarelli,Alan J. Thompson,J. M. Brady,Paul M. Matthews +13 more
TL;DR: The results provide the first quantitative demonstration of reliable inference of anatomical connectivity between human gray matter structures using diffusion data and the first connectivity-based segmentation of gray matter.
Journal ArticleDOI
The columnar organization of the neocortex.
TL;DR: The modular organization of nervous systems is a widely documented principle of design for both vertebrate and invertebrate brains of which the columnar organization of the neocortex is an example.
Related Papers (5)
Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
Complex network measures of brain connectivity: uses and interpretations.
Mikail Rubinov,Olaf Sporns +1 more