The Human Connectome: A Structural Description of the Human Brain
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TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
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Graph theoretical analysis indicates cognitive impairment in MS stems from neural disconnection
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Model-based whole-brain effective connectivity to study distributed cognition in health and disease.
Matthieu Gilson,Gorka Zamora-López,Vicente Pallarés,Mohit H. Adhikari,Mario Senden,Adrià Tauste Campo,Dante Mantini,Maurizio Corbetta,Maurizio Corbetta,Gustavo Deco,Gustavo Deco,Andrea Insabato +11 more
TL;DR: An overview of the model-based whole-brain effective connectivity to analyze fMRI data is provided, while discussing the pros and cons of the approach with respect to other established approaches and a comprehensive set of tools that open exciting perspectives to study distributed cognition, as well as neuropathologies are provided.
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The segregated connectome of late-life depression: a combined cortical thickness and structural covariance analysis.
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Tractography-Based Parcellation of the Cortex Using a Spatially-Informed Dimension Reduction of the Connectivity Matrix
TL;DR: This paper presents a method for connectivity-based parcellation of the entire human cortical surface, exploiting the idea that each cortex region has a specific connection profile.
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Can neuroimaging disentangle bipolar disorder
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References
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