The Human Connectome: A Structural Description of the Human Brain
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TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
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Dynamic Connectivity Detection: an algorithm for determining functional connectivity change points in fMRI data
Yuting Xu,Martin A. Lindquist +1 more
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Massimiliano Zanin,David Papo,Pedro Sousa,Ernestina Menasalvas,Andrea Nicchi,Elaine Kubik,Stefano Boccaletti +6 more
TL;DR: In this paper, an overview of both fields is provided, some fundamental concepts of which are illustrated, and a variety of contexts in which complex network theory and data mining have been used in a synergistic manner are presented.
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Bottom up modeling of the connectome: linking structure and function in the resting brain and their changes in aging.
TL;DR: An overview of a modeling approach of the resting brain network is presented and an application of a neural mass model in the study of complexity changes in aging is given.
Journal ArticleDOI
Influence of wiring cost on the large-scale architecture of human cortical connectivity.
TL;DR: This work performs a comparative analysis of a connectivity map of the cortical connectome both on high- and low-resolutions utilising three different types of surrogate networks: spatially unconstrained (‘random’, connection length preserving (’spatial’), and connection length optimised (�‘reduced’) surrogates).
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Towards a two-body neuroscience
TL;DR: The underlying issues and perspectives involved in elucidating the pathway from individual to social theories of cognition will be discussed, ranging from the choice of a common time-unit for behavioral and brain recordings to the creation of algorithms for data processing between distant brain regions in different brains.
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