The Human Connectome: A Structural Description of the Human Brain
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TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
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Hierarchy of information processing in the brain: A novel ‘intrinsic ignition’ framework
TL;DR: A new framework is proposed to capture the key principles of how local activity influences global computation, i.e., describing the propagation of information and thus the broadness of communication driven by local activity, to provide insight into the precise nature of hierarchical information processing.
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Brain and cognitive reserve: Translation via network control theory.
John D. Medaglia,Fabio Pasqualetti,Roy H. Hamilton,Sharon L. Thompson-Schill,Danielle S. Bassett +4 more
TL;DR: In this article, the authors describe the theoretical opportunities offered by the application of network control theory at the level of the human connectome to understand cognitive resilience and inform translational intervention.
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The structural connectivity of higher order association cortices reflects human functional brain networks
TL;DR: This study provides strong and direct evidence that core functional brain networks mirror the brain's structural connectivity and revealed five physically-connected sub-networks, which correspond directly to five known functional networks.
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Reproducibility of the Structural Brain Connectome Derived from Diffusion Tensor Imaging.
Leonardo Bonilha,Ezequiel Gleichgerrcht,Julius Fridriksson,Chris Rorden,Jesse Breedlove,Travis Nesland,Walter Paulus,Gunther Helms,Niels K. Focke +8 more
TL;DR: The results demonstrate that connectome mapping is a largely reproducible technique, particularly as it relates to the geometry of network architecture measured by graph theory methods.
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Gender consistency and difference in healthy adults revealed by cortical thickness.
Bin Lv,Jing Li,Huiguang He,Meng Li,Mingchang Zhao,Likun Ai,Fei Yan,Junfang Xian,Zhenchang Wang +8 more
TL;DR: The results showed that the significant gender-related differences of cortical thickness appeared extensively in the frontal, parietal and occipital lobes and there were also some between-group differences in the interregional correlation.
References
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