The Human Connectome: A Structural Description of the Human Brain
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TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.Abstract:
The connection matrix of the human brain (the human “connectome”) represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.read more
Citations
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Journal ArticleDOI
Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Complex network measures of brain connectivity: uses and interpretations.
Mikail Rubinov,Olaf Sporns +1 more
TL;DR: Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.
Journal ArticleDOI
Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
William W. Seeley,Vinod Menon,Alan F. Schatzberg,Jennifer Keller,Gary H. Glover,Heather A. Kenna,Allan L. Reiss,Michael D. Greicius +7 more
TL;DR: Two distinct networks typically coactivated during functional MRI tasks are identified, anchored by dorsal anterior cingulate and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an “executive-control network” that links dorsolateral frontal and parietal neocortices.
Journal ArticleDOI
Mapping the Structural Core of Human Cerebral Cortex
Patric Hagmann,Leila Cammoun,Xavier Gigandet,Reto Meuli,Christopher J. Honey,Van J. Wedeen,Olaf Sporns +6 more
TL;DR: The spatial and topological centrality of the core within cortex suggests an important role in functional integration and a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants.
Journal ArticleDOI
BrainNet Viewer: a network visualization tool for human brain connectomics.
Mingrui Xia,Jinhui Wang,Yong He +2 more
TL;DR: This work has developed a graph-theoretical network visualization toolbox, called BrainNet Viewer, to illustrate human connectomes as ball-and-stick models, and helps researchers to visualize brain networks in an easy, flexible and quick manner.
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