Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
Citations
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Journal ArticleDOI
Silver–Silica Nanocomposite Materials Incorporated into Textile Fabrics: Chemical and Biological Study
TL;DR: In this article, the morphology and size of silver nanoparticles inside the silica gel matrix were identified by transmission electron microscopy (TEM) and X-ray diffraction analysis (XRD).
Journal ArticleDOI
Effect of Flexibility and Size of Nanofabricated Topographies on the Mechanobactericidal Efficacy of Polymeric Surfaces.
TL;DR: In this paper , a facile, scalable, UV nano-imprint lithography method was used to fabricate nanopillar array topographies of variable sizes and flexibilities, and it was found that bacterial death on nanopillars in the range of diameters ≤100 nm and Young's moduli ≥ 1.3 GPa is increased by 3.5-to 5.6-fold while thicker or softer pillars did not reduce bacterial viability.
Journal ArticleDOI
Characterization of Polymer Waste Containing Nano-fillers Prior its End-of-Life Treatment
Dinh Trinh Tran,Aurélie Joubert,Danielle Venditti,Sylvain Durecu,Thierry Meunier,Olivier Le Bihan,Emmanuel Fiani,Laurence Le Coq +7 more
TL;DR: In this article, a polymer waste, originating from polyorganosiloxane polymerization processes, prior to its end-of-life treatment was characterized in order to identify and quantify the possibly contained nano-fillers.
Book ChapterDOI
Safer-by-design for nanomaterials
TL;DR: Safer-by-design strategies for engineered inorganic and carbonaceous nanomaterials mainly aim at reducing hazard and the release of nanomorphs to the environment as mentioned in this paper. But the focus as to hazard is often on aspects of the overall hazard or specific hazards.
Dissertation
Methods to Assess Presence and Biological Impact of Engineered Nanoparticles
TL;DR: Methods to Assess Presence and Biological Impact of Engineered Nanoparticles are presented to demonstrate the ability of nanofiltration to assess the presence and biological impact of nanoparticles in the environment.
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Journal ArticleDOI
Silver Colloid Nanoparticles: Synthesis, Characterization, and Their Antibacterial Activity
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Journal ArticleDOI
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