Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
Citations
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Simultaneous determination of the size and concentration of AgNPs in water samples by UV–vis spectrophotometry and chemometrics tools
TL;DR: A multivariate analytical method that simultaneously estimates the concentration and size of mixtures of silver nanoparticles (AgNPs) in environmental water samples based on changes in the surface plasmon resonance band of AgNPs when they form aggregated/assembled structures with L-cysteine.
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Hydrogen sulfide – cysteine cycle plays a positive role in Arabidopsis responses to Copper Oxide nanoparticles stress
Honglei Jia,Honglei Jia,Jun Yang,Huaxin Liu,Liu Kena,Peiyun Ma,Sisi Chen,Wei Shi,Wei Ting,Ren Xinhao,Guo Junkang,Jisheng Li +11 more
TL;DR: H2S-Cys cycle plays a positive role in plant responses to CuO NPs stress, and regulated antioxidase activity and maintained ROS homeostasis in CuONPs stress.
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Thermodynamic properties of nanostructured ZnO
TL;DR: In this paper, a comprehensive overview of the thermodynamic properties of nanostructured zinc oxide nanoparticles is provided, using a simple thermodynamic model, interpreting literary data on the influence of ZnO nanoparticle size and shape on the on the structural and chemical stability, solubility in water and aqueous solutions, and mutual miscibility with other oxides of metallic elements.
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Elemental copper nanoparticle toxicity to anaerobic ammonium oxidation and the influence of ethylene diamine-tetra acetic acid (EDTA) on copper toxicity.
Jorge Gonzalez-Estrella,Guangbin Li,Sarah E. Neely,Daniel Puyol,Reyes Sierra-Alvarez,Jim A. Field +5 more
TL;DR: Overall, this study indicates that Cu0 NP and CuCl2 are toxic to anammox, and furthermore, that EDTA attenuates Cu0NP andCuCl2 toxicity toAnammox by complexing Cu2+ ions.
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Assessment of copper nanoparticles (Cu-NPs) and copper (II) oxide (CuO) induced hemato- and hepatotoxicity in Cyprinus carpio.
Aasma Noureen,Farhat Jabeen,Tanveer A. Tabish,Sajid Yaqub,Muhammad Ali,Abdul Shakoor Chaudhry +5 more
TL;DR: It appeared that the Cu-NPs were more toxic than the CuO as shown by the hemato- and hepatotoxicity in C. carpio of this study.
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