Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
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TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
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Evaluation of the effect of test medium on total Cu body burden of nano CuO-exposed Daphnia magna: A TXRF spectroscopy study.
TL;DR: Despite the CuO NP toxicity mitigating effect of natural freshwater, total copper body burden of aquatic crustaceans in natural waterbodies may be greater than could be predicted based on the results obtained using artificial freshwater as the test medium.
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Ecotoxicological impacts of exposure to copper oxide nanoparticles on the gill of the Swan mussel, Anodonta cygnea (Linnaeus, 1758)
TL;DR: Investigation of the ecotoxicological effects of exposure to copper oxide nanoparticles (CuO NPs) on the gill of the swan mussel Anodonta cygnea found significant accumulation of CuONPs in the gills could affect histological and ultra-structural characteristics of this organ and consequently have deleterious impacts on its filtration activity.
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Contributions of Zn Ions to ZnO Nanoparticle Toxicity on Microcystis aeruginosa During Chronic Exposure
TL;DR: Different results indicate that the insoluble NPs during the initial exposure mostly account for lipid peroxidation, which further lead to microalgal antioxidant response, and during the subsequent exposure, the contributors of ZnO NP toxicity shift with the concentration and exposure time.
Journal ArticleDOI
Chiral ionic liquid assisted synthesis of some metal oxides
Elena Husanu,Valentina Cappello,Christian Silvio Pomelli,Jérémy David,Mauro Gemmi,Cinzia Chiappe +5 more
TL;DR: In this article, a chiral ionic liquid with a natural alcohol based chain was used as a tailoring agent for the synthesis of simple and cost effective materials such as ZnO, CuO, and CuO-ZnO with peculiar morphology.
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Photocatalytic activity of ZNO with different morphologies synthesized by a sonochemical method
TL;DR: In this article, different morphologies of ZnO structures were successfully synthesized in precursor solutions with the pH of 8, 9, 10, 11, and 12 by a sonochemical method at room temperature.
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