Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
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TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
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Biologically Reduced Zinc Oxide Nanosheets Using Phyllanthus emblica Plant Extract for Antibacterial and Dye Degradation Studies
Awais Khalid,Pervaiz Ahmad,Mayeen Uddin Khandaker,Yosra Ahmad Modafer,Hanadi A. Almukhlifi,Abdulrahman S. Bazaid,Abdu Hussein A. Aldarhami,Abdulaziz M. Alanazi,Ohoud Jefri,M. J. Uddin,Husam Qanash +10 more
TL;DR: In this article , an overview of the biosynthesis of zinc oxide (ZnO) nanosheets (NSs) using Phyllanthus emblica plant (PEP) extract was provided.
Journal ArticleDOI
Effectiveness and safety of zinc oxide nanoparticle-coated socks compared to uncoated socks for the prevention of pitted keratolysis: a double-blinded, randomized, controlled trial study.
Punyawee Ongsri,Charussri Leeyaphan,Pichaya Limphoka,Rungsima Kiratiwongwan,Sumanas Bunyaratavej +4 more
TL;DR: In this paper, a double-blinded, randomized, controlled trial was conducted in January 2019, where zinc oxide nanoparticles (ZnO-NPs) were used to prevent the development of pitted keratolysis and bromodosis in military personnel.
Journal ArticleDOI
Fungicidal Activity of Zinc Oxide Nanoparticles against Azole-Resistant Aspergillus flavus Isolated from Yellow and White Maize
Nuha M. Alhazmi,Eman M. Sharaf +1 more
TL;DR: In this article , the authors used zinc oxide nanoparticles associated with Chlorella vulgaris, which are synthesized by using the precipitation method, to isolate azole-resistant Aspergillus flavus from two sources of maize.
Journal ArticleDOI
Metal transfer to sediments, invertebrates and fish following waterborne exposure to silver nitrate or silver sulfide nanoparticles in an indoor stream mesocosm.
Nathaniel J. Clark,Josanne Vassallo,Patrícia V. Silva,Ana Rita R. Silva,Marta Baccaro,Neja Medvešček,Maja Grgic,Abel L.G. Ferreira,Martí Busquets-Fité,Kerstin Jurkschat,Anastasios G. Papadiamantis,Víctor F. Puntes,I. Lynch,Claus Svendsen,Nico W. van den Brink,Cornelis A.M. van Gestel,Susana Loureiro,Richard D. Handy +17 more
TL;DR: In this article , an aquatic stream mesocosm explored the fate and bioaccumulation of silver sulfide nanoparticles (Ag2S NPs) compared to silver nitrate (AgNO3).
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