Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
Citations
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Kraft lignin/silica-AgNPs as a functional material with antibacterial activity.
Łukasz Klapiszewski,Tomasz Rzemieniecki,Magdalena Krawczyk,Dagmara Malina,Małgorzata Norman,Jakub Zdarta,Izabela Majchrzak,Anna Dobrowolska,Katarzyna Czaczyk,Teofil Jesionowski +9 more
TL;DR: The addition of silver nanoparticles to the silica/lignin hybrids led to inhibition of the growth of the analyzed bacteria, and the best results were obtained against Pseudomonas aeruginosa, a dangerous human pathogen.
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In vitro cytotoxicity of silver nanoparticles and zinc oxide nanoparticles to human epithelial colorectal adenocarcinoma (Caco-2) cells.
TL;DR: Ag NPs are safer antibacterial material in food packaging materials than ZnO NPs, and the toxicity mechanism of nanoparticles on Caco-2 cells in vitro is discovered.
Journal ArticleDOI
Effect of zinc oxide amounts on the properties and antibacterial activities of zeolite/zinc oxide nanocomposite.
Abdullah A. Alswat,Abdullah A. Alswat,Mansor Bin Ahmad,Tawfik A. Saleh,Mohd Zobir Hussein,Nor Azowa Ibrahim +5 more
TL;DR: Zeolite/ZnO NCs showed noticeable antibacterial activities against the tested bacteria; Gram- positive and Gram- negative bacteria, under normal light.
Journal ArticleDOI
Environmental and health impacts of fine and ultrafine metallic particles: Assessment of threat scores
Sylvaine Goix,Thibaut Leveque,Tiantian Xiong,Eva Schreck,Armelle Baeza-Squiban,Florence Geret,Gaëlle Uzu,Annabelle Austruy,Camille Dumat +8 more
TL;DR: Global threat scores to prioritize the harmfulness of anthropogenic fine and ultrafine metallic particles (FMP) emitted into the atmosphere at the global scale are proposed and could be widely used in various contexts of pollution by complex metal particles and may improve risk management.
Journal ArticleDOI
How should the completeness and quality of curated nanomaterial data be evaluated
Richard L. Marchese Robinson,Iseult Lynch,Willie J.G.M. Peijnenburg,John Rumble,Fred Klaessig,Clarissa Marquardt,Hubert Rauscher,Tomasz Puzyn,Ronit Purian,Christoffer Åberg,Sandra C. Karcher,Hanne Vriens,Peter Hoet,Mark D. Hoover,Christine Ogilvie Hendren,Stacey L. Harper +15 more
TL;DR: The current article, part of the Nanomaterial Data Curation Initiative series, addresses how to assess the completeness and quality of (curated) nanomaterial data.
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