Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review
Olesja Bondarenko,Katre Juganson,Katre Juganson,Angela Ivask,Kaja Kasemets,Monika Mortimer,Monika Mortimer,Anne Kahru +7 more
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TLDR
The toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.Abstract:
Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic organisms. This review summarizes the recent research on (eco)toxicity of silver (Ag), CuO and ZnO NPs. Organism-wise it focuses on key test species used for the analysis of ecotoxicological hazard. For comparison, the toxic effects of studied NPs toward mammalian cells in vitro were addressed. Altogether 317 L(E)C50 or minimal inhibitory concentrations (MIC) values were obtained for algae, crustaceans, fish, bacteria, yeast, nematodes, protozoa and mammalian cell lines. As a rule, crustaceans, algae and fish proved most sensitive to the studied NPs. The median L(E)C50 values of Ag NPs, CuO NPs and ZnO NPs (mg/L) were 0.01, 2.1 and 2.3 for crustaceans; 0.36, 2.8 and 0.08 for algae; and 1.36, 100 and 3.0 for fish, respectively. Surprisingly, the NPs were less toxic to bacteria than to aquatic organisms: the median MIC values for bacteria were 7.1, 200 and 500 mg/L for Ag, CuO and ZnO NPs, respectively. In comparison, the respective median L(E)C50 values for mammalian cells were 11.3, 25 and 43 mg/L. Thus, the toxic range of all the three metal-containing NPs to target- and non-target organisms overlaps, indicating that the leaching of biocidal NPs from consumer products should be addressed.read more
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Antibacterial ability of immobilized silver nanoparticles in agar-agar films co-doped with magnesium ions.
Slađana Davidović,Vesna Lazić,Miona G. Miljković,Milan Gordić,Milica Sekulić,Milena Marinović-Cincović,Ishara Ratnayake,S. Phillip Ahrenkiel,Jovan M. Nedeljković +8 more
TL;DR: Thermogravimetric analysis, as well as the determination of tensile strength, Young's modulus, and elongation at break showed improvement of thermal stability and mechanical properties of agar-agar matrices upon the incorporation of Ag NPs due to high compatibility between the hydrophilic organic component and inorganic components.
Journal ArticleDOI
Stability and toxicity of differently coated selenium nanoparticles under model environmental exposure settings.
Atiđa Selmani,Lea Ulm,Kaja Kasemets,Imbi Kurvet,Ina Erceg,Rinea Barbir,Barbara Pem,Paula Santini,Ida Delač Marion,Tomislav Vinković,Adela Krivohlavek,Maja Dutour Sikirić,Anne Kahru,Anne Kahru,Ivana Vinković Vrček +14 more
TL;DR: Although SeNPs have attracted great interest for use in biomedicine, this study demonstrated that their ecotoxicological effects should be considered during the design of new of SeNPS-based products.
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Anti-Periprosthetic Infection Strategies: From Implant Surface Topographical Engineering to Smart Drug-Releasing Coatings
Ananta Ghimire,Jie Song +1 more
TL;DR: A review of anti-periprosthetic infection strategies aimed at either reducing bacterial adhesion, colonization, and biofilm formation or killing bacteria directly in contact with and/or in the vicinity of implants is presented in this article.
Ecotoxicological Evaluation of Shale Fuel Oils, Metal-Based Nanoparticles and Glyphosate Formulations
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Book ChapterDOI
The Toxicity of Nanoparticles to Organisms in Freshwater.
TL;DR: The impacts of environmental exposure to NPs, the influence of the physicochemical characteristics of NPs and the surrounding environment on toxicity and mechanisms of toxicity together with NP bioaccumulation and trophic transfer are assessed with a focus on their impacts on bacteria, algae and daphnids.
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