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Ben Caplin

Researcher at University College London

Publications -  63
Citations -  1478

Ben Caplin is an academic researcher from University College London. The author has contributed to research in topics: Kidney disease & Population. The author has an hindex of 19, co-authored 52 publications receiving 991 citations. Previous affiliations of Ben Caplin include Imperial College London & Medical Research Council.

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Patients' perspective of haemodialysis-associated symptoms

TL;DR: Despite advances in HD, intradialytic symptoms were frequently reported by patients, and there was substantial unexplained variation in symptom burden across centres, suggesting that clinical practice or policies may play a role in preventing the adverse effects of dialysis.
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Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

Obbina Abani, +7885 more
- 03 Mar 2022 - 
TL;DR: In patients hospitalised with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials.
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Endogenous Nitric Oxide Synthase Inhibitors in the Biology of Disease: Markers, Mediators, and Regulators?

TL;DR: This review outlines the basic biochemistry and physiology of endogenous methylarginines, examines both the experimental and observational evidence for a role in disease pathogenesis, and examines the potential for therapeutic regulation of these molecules.
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Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1

TL;DR: It is demonstrated that common variation at C1GALT1 influences Gd-IgA1 level in the population, which independently associates with risk of progressive IgAN, and that the pathogenic importance of changes in IgA1 O-glycosylation may vary between white and Chinese patients with IgAN.
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Alanine-Glyoxylate Aminotransferase-2 Metabolizes Endogenous Methylarginines, Regulates NO, and Controls Blood Pressure

TL;DR: Findings suggest that AGXT2 is an important regulator of methylarginines and represents a novel mechanism through which the kidney regulates blood pressure.