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Giuseppe Paolisso
Researcher at Seconda Università degli Studi di Napoli
Publications - 518
Citations - 36557
Giuseppe Paolisso is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 85, co-authored 479 publications receiving 33028 citations. Previous affiliations of Giuseppe Paolisso include National Institutes of Health & University of Udine.
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Journal ArticleDOI
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Josée Dupuis,Josée Dupuis,Claudia Langenberg,Inga Prokopenko,Richa Saxena,Richa Saxena,Nicole Soranzo,Nicole Soranzo,Anne U. Jackson,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Anna L. Gloyn,Cecilia M. Lindgren,Reedik Mägi,Andrew P. Morris,Joshua C. Randall,Toby Johnson,Toby Johnson,Paul Elliott,Paul Elliott,Denis Rybin,Gudmar Thorleifsson,Valgerdur Steinthorsdottir,Peter Henneman,Harald Grallert,Abbas Dehghan,Jouke JanHottenga,Christopher S. Franklin,Pau Navarro,Kijoung Song,Anuj Goel,John R. B. Perry,Josephine M. Egan,Taina K. Lajunen,Niels Grarup,Thomas Sparsø,Alex S. F. Doney,Benjamin F. Voight,Benjamin F. Voight,Heather M. Stringham,Man Li,Stavroula Kanoni,Peter Shrader,Christine Cavalcanti-Proença,Meena Kumari,Lu Qi,Nicholas J. Timpson,Christian Gieger,Carina Zabena,Ghislain Rocheleau,Erik Ingelsson,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,Amanda F. Elliott,Amanda F. Elliott,Steven A. McCarroll,Steven A. McCarroll,Felicity Payne,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Kristin Ardlie,Yavuz Ariyurek,Beverley Balkau,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Rafn Benediktsson,Amanda J. Bennett,Sven Bergmann,Sven Bergmann,Murielle Bochud,Eric Boerwinkle,Amélie Bonnefond,Lori L. Bonnycastle,Knut Borch-Johnsen,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Guillaume Charpentier,Yii Der IdaChen,Peter S. Chines,Robert Clarke,Lachlan J. McOin,Mark E. Cooper,Marilyn C. Cornelis,Gabe Crawford,Laura Crisponi,Ian N. M. Day,Eco J. C. de Geus,Jérôme Delplanque,Christian Dina,Michael R. Erdos,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Rune R. Frants,Maria GraziaFranzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Christopher J. Groves,Scott M. Grundy,Rhian Gwilliam,Ulf Gyllensten,Samy Hadjadj,Göran Hallmans,Naomi Hammond,Xijing Han,Anna LiisaHartikainen,Neelam Hassanali,Caroline Hayward,Simon Heath,Serge Hercberg,Christian Herder,Andrew A. Hicks,David R. Hillman,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Joseph Hung,Bo Isomaa,Paul Johnson,Torben Jørgensen,Antti Jula,Marika Kaakinen,Jaakko Kaprio,Jaakko Kaprio,Y. AnteroKesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G. Mark Lathrop,Debbie A Lawlor,Olivier Le Bacquer,Cécile Lecoeur,Yun Li,Valeriya Lyssenko,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María TeresaMartínez-Larrad,Jarred B. McAteer,Jarred B. McAteer,Laura J. McCulloch,Ruth McPherson,Christa Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,Mario A. Morken,Sutapa Mukherjee,Silvia Naitza,Narisu Narisu,Matt Neville,Ben A. Oostra,Marco Orrù,Ruth E. Pakyz,Colin N. Apalmer,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,John F. Peden,Nancy L. Pedersen,Markus Perola,Markus Perola,Andreas Pfeiffer,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,Anneli Pouta,Michael A. Province,Bruce M. Psaty,Bruce M. Psaty,Wolfgang Rathmann,Nigel W. Rayner,Kenneth Rice,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Michael Roden,Olov Rolandsson,Annelli Sandbæk,Manjinder S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Laura J. Scott,Udo Seedorf,Stephen J. Sharp,Beverley M. Shields,Gunnar Sigursson,Eric J.G. Sijbrands,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Nicholas L. Smith,Ulla Sovio,Amy J. Swift,Holly E. Syddall,Ann ChristineSyvänen,Toshiko Tanaka,Toshiko Tanaka,Barbara Thorand,Jean Tichet,Anke Tönjes,Tiinamaija Tuomi,André G. Uitterlinden,Ko Willems van Dijk,Mandy van Hoek,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,Nicole Vogelzangs,Gerard Waeber,Peter Wagner,Peter Wagner,Andrew Walley,G. BragiWalters,Kim L. Ward,Hugh Watkins,Michael N. Weedon,Sarah H. Wild,Gonneke Willemsen,Jaqueline C. MWitteman,John W. GYarnell,Eleftheria Zeggini,Eleftheria Zeggini,Diana Zelenika,Björn Zethelius,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. Carola Zillikens,Ingrid B. Borecki,Ruth J. F. Loos,Pierre Meneton,Patrik K. E. Magnusson,David M. Nathan,Gordon H. Williams,Andrew T. Hattersley,Kaisa Silander,Kaisa Silander,Veikko Salomaa,George Davey Smith,Stefan R. Bornstein,Peter Schwarz,Joachim Spranger,Fredrik Karpe,Alan R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Andrew D. Morris,Lars Lind,Lyle J. Palmer,Lyle J. Palmer,Frank B. Hu,Paul W. Franks,Shah Ebrahim,Michael Marmot,W. H. Linda Kao,James S. Pankow,Mike Sampson,Johanna Kuusisto,Markku Laakso,Torben Hansen,Torben Hansen,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Peter P. Pramstaller,H.-Erich Wichmann,Thomas Illig,Igor Rudan,Igor Rudan,Alan F. Wright,Michael Stumvoll,Harry Campbell,James F. Wilson,Richard N. Bergman,Thomas A. Buchanan,Francis S. Collins,Karen L. Mohlke,Jaakko Tuomilehto,Jaakko Tuomilehto,Timo T. Valle,David Altshuler,David Altshuler,Jerome I. Rotter,David S. Siscovick,Brenda W.J.H. Penninx,Dorret I. Boomsma,Panos Deloukas,Tim D. Spector,Tim D. Spector,Timothy M. Frayling,Luigi Ferrucci,Augustine Kong,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Cornelia M. van Duijn,Yurii S. Aulchenko,Antonio Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Marjo Riitta-Järvelin,Marjo Riitta-Järvelin,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Vincent Mooser,Gonçalo R. Abecasis,Nicholas J. Wareham,Robert Sladek,Philippe Froguel,Philippe Froguel,Richard M. Watanabe,James B. Meigs,Leif Groop,Michael Boehnke,Mark I. McCarthy,Jose C. Florez,Jose C. Florez,Inês Barroso +339 more
TL;DR: It is demonstrated that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes.
Journal ArticleDOI
Oxidative Stress and Diabetic Vascular Complications
TL;DR: The suggestion that the different susceptibility of diabetic patients to microvascular and macrovascular complications may be a function of the endogenous antioxidant status is suggested.
Journal ArticleDOI
A genome-wide association search for type 2 diabetes genes in African Americans.
Nichole D. Palmer,Caitrin W. McDonough,Pamela J. Hicks,B H Roh,M R Wing,S S An,Jessica M. Hester,Jessica N. Cooke,Meredith A. Bostrom,Megan E. Rudock,Matthew E. Talbert,Joshua P. Lewis,Assiamira Ferrara,Lingyi Lu,Julie T. Ziegler,Michèle M. Sale,Jasmin Divers,Daniel Shriner,Adebowale Adeyemo,Charles N. Rotimi,Ng Mcy.,Carl D. Langefeld,Barry I. Freedman,Donald W. Bowden,Benjamin F. Voight,Laura J. Scott,Valgerdur Steinthorsdottir,Andrew P. Morris,Christian Dina,Ryan P. Welch,Eleftheria Zeggini,Cornelia Huth,Yurii S. Aulchenko,Gudmar Thorleifsson,Laura J. McCulloch,Teresa Ferreira,Harald Grallert,Najaf Amin,Guanming Wu,Cristen J. Willer,Soumya Raychaudhuri,Steven A. McCarroll,Claudia Langenberg,O M Hofmann,Josée Dupuis,Lu Qi,A V Segrè,M. van Hoek,Pau Navarro,Kristin G. Ardlie,Beverley Balkau,Rafn Benediktsson,Amanda J. Bennett,Roza Blagieva,Eric Boerwinkle,Lori L. Bonnycastle,Kristina Bengtsson Boström,Bert Bravenboer,Suzannah Bumpstead,N P Burtt,Guillaume Charpentier,Peter S. Chines,Marilyn C. Cornelis,David Couper,Gabriel Crawford,Doney Asf.,Kathryn Elliott,A L Elliott,Michael R. Erdos,Caroline S. Fox,Christopher S. Franklin,Martha Ganser,Christian Gieger,Niels Grarup,Todd Green,Simon J. Griffin,C J Groves,Candace Guiducci,Samy Hadjadj,N Hassanali,C. Herder,Bo Isomaa,Anne U. Jackson,Johnson Prv.,Torben Jørgensen,Kao Whl.,N Klopp,Augustine Kong,Peter Kraft,Johanna Kuusisto,Torsten Lauritzen,Man Li,Aloysius G Lieverse,Cecilia M. Lindgren,Valeriya Lyssenko,Meghan L. Marré,Thomas Meitinger,Kristian Midthjell,Mario A. Morken,Narisu Narisu,P. M. Nilsson,Katharine R. Owen,Felicity Payne,Perry Jrb.,Petersen A-K.,Carl G. P. Platou,Christine Proença,Inga Prokopenko,Wolfgang Rathmann,N W Rayner,Neil R. Robertson,Ghislain Rocheleau,Michael Roden,Mike Sampson,Richa Saxena,B M Shields,Peter Shrader,Gunnar Sigurdsson,Thomas Sparsø,Klaus Strassburger,Heather M. Stringham,Qi Sun,Amy J. Swift,Barbara Thorand,Jean Tichet,Tiinamaija Tuomi,R. M. van Dam,T.W. van Haeften,T van Herpt,J. V. van Vliet-Ostaptchouk,G B Walters,Michael N. Weedon,Cisca Wijmenga,Jacqueline C. M. Witteman,Richard N. Bergman,Stéphane Cauchi,Francis S. Collins,Anna L. Gloyn,Ulf Gyllensten,Torben Hansen,Winston Hide,Graham A. Hitman,Albert Hofman,David J. Hunter,Kristian Hveem,Markku Laakso,Karen L. Mohlke,Andrew D. Morris,Palmer Cna.,Peter P. Pramstaller,Igor Rudan,Eric J.G. Sijbrands,Lincoln D. Stein,Jaakko Tuomilehto,A.G. Uitterlinden,M Walker,Nicholas J. Wareham,Richard M. Watanabe,Gonçalo R. Abecasis,Bernhard O. Boehm,Harry Campbell,Mark J. Daly,Andrew T. Hattersley,Frank B. Hu,James B. Meigs,James S. Pankow,Oluf Pedersen,Wichmann H-E.,Inês Barroso,Jose C. Florez,Timothy M. Frayling,Leif Groop,R Sladek,Unnur Thorsteinsdottir,James F. Wilson,Thomas Illig,Philippe Froguel,C M van Duijn,Kari Stefansson,David Altshuler,Michael Boehnke,Mark I. McCarthy,Nicole Soranzo,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Reedik Mägi,Joshua C. Randall,Toby Johnson,Paul Elliott,Denis Rybin,Peter Henneman,Abbas Dehghan,Jouke-Jan Hottenga,Kijoung Song,Anuj Goel,Josephine M. Egan,Taina K. Lajunen,Alex S. F. Doney,Stavroula Kanoni,Christine Cavalcanti-Proença,Meena Kumari,Nicholas J. Timpson,Carina Zabena,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,Amanda F. Elliott,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Yavuz Ariyurek,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Sven Bergmann,Murielle Bochud,Amélie Bonnefond,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Chen Y-Di.,Peter S. Chines,Robert Clarke,Coin Ljm.,Mark E. Cooper,Laura Crisponi,Day Inm.,de Geus Ejc.,Jérôme Delplanque,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,R.R. Frants,MariaGrazia Franzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Scott M. Grundy,R. Gwilliam,Göran Hallmans,Naomi Hammond,Xijing Han,Hartikainen A-L.,Caroline Hayward,Simon C. Heath,Serge Hercberg,Andrew A. Hicks,David R. Hillman,Aroon D. Hingorani,Jennie Hui,Joseph Hung,A. Jula,Marika Kaakinen,Jaakko Kaprio,Y A Kesaniemi,Mika Kivimäki,Beatrice Knight,Sini Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G M Lathrop,Debbie A Lawlor,O Le Bacquer,Cécile Lecoeur,Yun Li,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María Teresa Martínez-Larrad,Jarred B. McAteer,Ruth McPherson,Christine Meisinger,David Melzer,David Meyre,B. D. Mitchell,Sutapa Mukherjee,Silvia Naitza,Matt J. Neville,B.A. Oostra,Marco Orrù,Ruth E. Pakyz,Giuseppe Paolisso,C. Pattaro,D. Pearson,John F. Peden,Nancy L. Pedersen,M. Perola,Pfeiffer Afh.,Irene Pichler,Ozren Polašek,Danielle Posthuma,Simon C. Potter,Anneli Pouta,M. A. Province,Bruce M. Psaty,Kenneth Rice,Samuli Ripatti,F. Rivadeneira,Olov Rolandsson,A. Sandbaek,M. S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Udo Seedorf,Stephen J. Sharp,Beverley M. Shields,Sijbrands Ejg.,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Ulla Sovio,A J Swift,H E Syddall,Syvänen A-C.,Toshiko Tanaka,Anke Tönjes,Andre G. Uitterlinden,K W van Dijk,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,Nicole Vogelzangs,Gerard Waeber,P J Wagner,Andrew Walley,Kim L. Ward,Hugh Watkins,Sarah H. Wild,Gonneke Willemsen,Witteman Jcm.,Yarnell Jwg.,Diana Zelenika,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. C. Zillikens,Ingrid B. Borecki,Loos Rjf.,Pierre Meneton,Magnusson Pke.,David M. Nathan,Gordon H. Williams,Kaisa Silander,Veikko Salomaa,George Davey Smith,Stefan R. Bornstein,Peter Schwarz,Jochen Spranger,F Karpe,Alan R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Lars Lind,Lyle J. Palmer,Paul W. Franks,Shah Ebrahim,Michael Marmot,Alan F. Wright,Michael Stumvoll,Anders Hamsten,Thomas A. Buchanan,Timo T. Valle,Jerome I. Rotter,David S. Siscovick,Penninx Bwjh.,Dorret I. Boomsma,Panos Deloukas,Tim D. Spector,Luigi Ferrucci,Anyuan Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Jarvelin M-R.,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Vincent Mooser +384 more
TL;DR: It is suggested that multiple loci underlie T2DM susceptibility in the African-American population and that these loci are distinct from those identified in other ethnic populations.
Journal Article
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)
Josée Dupuis,Claudia Langenberg,Inga Prokopenko,Richa Saxena,Nicole Soranzo,Anne U. Jackson,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Anna L. Gloyn,C M Lindgren,Reedik Mägi,Andrew P. Morris,Joshua C. Randall,Toby Johnson,Peter J. Elliott,D Rybin,Gudmar Thorleifsson,Steinthorsdottir,Peter Henneman,H Grallert,Abbas Dehghan,J-J Hottenga,Christopher S. Franklin,Pau Navarro,KJ Song,Anuj Goel,Jrb Perry,Josephine M. Egan,Taina K. Lajunen,Niels Grarup,Thomas Sparsø,Alex S. F. Doney,B F Voight,Heather M. Stringham,Man Li,Stavroula Kanoni,Peter Shrader,Christine Cavalcanti-Proença,Meena Kumari,Lu Qi,N J Timpson,Christian Gieger,Carina Zabena,Ghislain Rocheleau,Erik Ingelsson,Ping An,Jeffery R. O'Connell,Jian'an Luan,Amanda F. Elliott,Steve McCarroll,Felicity Payne,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Kristin G. Ardlie,Yavuz Ariyurek,B. Balkau,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Rafn Benediktsson,Amanda J. Bennett,Sven Bergmann,Murielle Bochud,Eric Boerwinkle,Amélie Bonnefond,Lori L. Bonnycastle,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Guillaume Charpentier,Ydi Chen,Peter S. Chines,Robert Clarke,Ljm Coin,Mark E. Cooper,Marilyn C. Cornelis,Gabriel Crawford,Laura Crisponi,Inm Day,Ejc de Geus,Jérôme Delplanque,Christian Dina,Erdos,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,Caroline S. Fox,Rune R. Frants,MariaGrazia Franzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,C J Groves,Scott M. Grundy,R. Gwilliam,Ulf Gyllensten,Samy Hadjadj,Göran Hallmans,Naomi Hammond,Xijing Han,A.-L. Hartikainen,N Hassanali,Caroline Hayward,Simon C. Heath,Serge Hercberg,Christian Herder,Andrew A. Hicks,Hillman,Aroon D. Hingorani,A. Hofman,Jennie Hui,Joseph Hung,Bo Isomaa,Prv Johnson,Torben Jørgensen,A. Jula,Marika Kaakinen,J Kaprio,Y A Kesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G. M. Lathrop,Debbie A Lawlor,O Le Bacquer,C. Lecoeur,Yun Li,Lyssenko,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María Teresa Martínez-Larrad,Jarred B. McAteer,Laura J. McCulloch,Ruth McPherson,Christine Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,M. A. Morken,Sutapa Mukherjee,Silvia Naitza,Narisu Narisu,Matt J. Neville,Ben A. Oostra,Marco Orrù,Ruth E. Pakyz,Cna Palmer,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,J F Peden,Nancy L. Pedersen,M. Perola,Afh Pfeiffer,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,A Pouta,M. A. Province,Bruce M. Psaty,Wolfgang Rathmann,N W Rayner,Kenneth Rice,S. Ripatti,Fernando Rivadeneira,Michael Roden,Olov Rolandsson,A. Sandbaek,M. S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Laura J. Scott,Udo Seedorf,Stephen J. Sharp,B M Shields,G Sigurosson,Ejg Sijbrands,Angela Silveira,Laila Simpson,AB Singleton,Nicholas L. Smith,Ulla Sovio,Amy J. Swift,Holly E. Syddall,Ann-Christine Syvänen,Toshiko Tanaka,Barbara Thorand,Jean Tichet,A Tönjes,Tiinamaija Tuomi,A.G. Uitterlinden,K W van Dijk,M. van Hoek,Dhiraj Varma,Sophie Visvikis-Siest,Vitart,Nicole Vogelzangs,G. Waeber,P J Wagner,Andrew Walley,G B Walters,Kim L. Ward,Hugh Watkins,Michael N. Weedon,Sarah H. Wild,Gonneke Willemsen,Jcm Witteman,Jwg Yarnell,E Zeggini,Diana Zelenika,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. C. Zillikens,Ingrid B. Borecki,Rjf Loos,Pierre Meneton,Pke Magnusson,David M. Nathan,Gordon H. Williams,Andrew T. Hattersley,Kaisa Silander,Salomaa,George Davey Smith,Bornstein,Peter Schwarz,Jochen Spranger,F Karpe,A. R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Andrew D. Morris,Lars Lind,Lyle J. Palmer,Frank B. Hu,Paul W. Franks,S Ebrahim,Michael Marmot,Whl Kao,James S. Pankow,Mike Sampson,Johanna Kuusisto,Markku Laakso,T. Hansen,Oluf Pedersen,Peter P. Pramstaller,Heinz Erich Wichmann,Thomas Illig,Igor Rudan,Alan F. Wright,Michael Stumvoll,Harry Campbell,James F. Wilson,Anders Hamsten,Richard N. Bergman,Thomas A. Buchanan,F. S. Collins,Karen L. Mohlke,J. Tuomilehto,Valle Tt,David Altshuler,Jerome I. Rotter,David S. Siscovick,Bwjh Penninx,D.I. Boomsma,Panagiotis Deloukas,Tim D. Spector,Timothy M. Frayling,L Ferrucci,Augustine Kong,Unnur Thorsteinsdottir,Kari Stefansson,C M van Duijn,Y S Aulchenko,Anyuan Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Jarvelin,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Mooser,Gonçalo R. Abecasis,Nicholas J. Wareham,Robert Sladek,Philippe Froguel,Richard M. Watanabe,James B. Meigs,Leif Groop,Michael Boehnke,Mark I. McCarthy,Jose C. Florez,Ines Barroso Magic Investigators +303 more
Journal ArticleDOI
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
Adrian F. Hernandez,Jennifer B. Green,Salim Janmohamed,Ralph B. D'Agostino,Christopher B. Granger,Nigel P. Jones,Lawrence A. Leiter,Anne E Rosenberg,Kristina N Sigmon,Matthew C Somerville,Karl M. Thorpe,John J.V. McMurray,Stefano Del Prato,Robert M. Califf,Rury R. Holman,David L. DeMets,Matthew C. Riddle,Shaun G. Goodman,Darren K. McGuire,Karen P. Alexander,Adam D. DeVore,Chiara Melloni,Chetan B. Patel,David F. Kong,Gerald S. Bloomfield,Matthew T. Roe,Pierluigi Tricoci,Robert W. Harrison,Renato D. Lopes,Robin Mathews,Rajendra H. Mehta,William S Jones,Sreekanth Vemulapalli,Thomas J. Povsic,Zubin J. Eapen,Keith Dombrowski,Brad J. Kolls,Dedrick Jordan,Andrew P. Ambrosy,Stephen J. Greene,Aditya Mandawat,Jay Shavadia,Lauren B. Cooper,Abhinav Sharma,Patrícia O. Guimarães,Daniel Friedman,Matthew Wilson,Patricia Endsley,Tracy Gentry,Jeannie Collier,Kathleen Perez,Kourtnei James,Jennifer Roush,Connie Pope,Christina Howell,Megan Johnson,Matt Bailey,Joanna Cole,Teresa Akers,Beth Vandyne,Betsy Thomas,Jenny Rich,Susan Bartone,Gail Beaulieu,Kim Brown,Tuan Chau,Tamra Christian,Rebecca Coker,Deb Greene,Trevorlyn Haddock,Wendy Jenkins,Ghazala Haque,Marsha L. Marquess,Jean Pesarchick,Renee Rethaford,Allegra E. Stone,Firas Al Kawas,Michelle Anderson,Robert Enns,Isaac Sinay,Chantal Mathieu,Victor Yordanov,Irene Hramiak,Martin Haluzik,Søren Galatius,Bruno Guerci,Michael A. Nauck,Ilias Migdalis,Choon Beng Kathryn Tan,Gyozo Kocsis,Andrea Giaccari,Moon Kyu Lee,Ernesto German Cardona Muñoz,Jan H. Cornel,Kåre I. Birkeland,Miguel De Tezanos Pinto,Louie Tirador,Martyna Olesinska-Mader,Marina Shestakova,Larry A. Distiller,Jose Lopez-Sendon,Björn Eliasson,Chern-En Chiang,Suphot Srimahachota,Boris Mankovsky,M. Angelyn Bethel,Kathleen Dungan,Mikhail Kosiborod,Andres F Alvarisqueta,Jorge Baldovino,Diego Besada,Pedro R F Calella,Maria Cecilia Cantero,Patricia Castaño,Alejandro Chertkoff,Jesus Cuadrado,Luis De Loredo,Andrea Dominguez,Maria Vanesa Español,Hernan Finkelstein,Gustavo Frechtel,José O Fretes,Natalia Garrido Santos,Joaquin Gonzalez,Marcos Litvak,Juan Loureyro,Laura Maffei,Natacha Maldonado,Diego Mohr Gasparini,Silvia I Orio,Federico C Perez Manghi,Nelson Rodriguez Papini,Jorgelina Sala,Pablo Schygiel,Georgina Sposetti,Maria Rosa Ulla,Fernando Verra,Silvina Zabalua,Cesar J Zaidman,Laurent Crenier,Corinne Debroye,Francis Duyck,André Scheen,Luc Van Gaal,Chris Vercammen,Velichka Damyanova,Stefan Dimitrov,Snezhina Kovacheva,Lachezar Lozanov,Viktor Margaritov,Rositsa Mihaylova-Shumkova,Antoaneta Nikolaeva,Zhasmina Stoyanova,Ronald Akhras,Yves Beaudry,Jacques Bedard,Joseph Berlingieri,Raja Chehayeb,Stephen Cheung,James Conway,Jean Cusson,Anthony Della Siega,Richard Dumas,Peter Dzongowski,Murdo Ferguson,Daniel Gaudet,F.R. Grondin,Anil Gupta,Milan Gupta,Frank Halperin,Pierre-Alain Houle,Michael P. Jones,Simon Kouz,Christopher Kovacs,Daniel Landry,Eva Lonn,William O'Mahony,Sean Peterson,Dennis Reich,Alan Rosenbloom,Francois St-Maurice,Barna Tugwell,Saul Vizel,Vincent Woo,Tomas Brychta,Vladimir Cech,Eva Dvorakova,Tomas Edelsberger,Katarina Halciakova,Jarmila Krizova,Jiri Lastuvka,Martin Piperek,Vera Prymkova,Lea Raclavska,Elena Silhova,Robin Urbanek,Jan Vrkoc,Ulla Andersen,Jens Brønnum-Schou,Jens D. Hove,Jan Skov Jensen,Lars Køber,Ole Peter Kristiansen,Per Lund,Thomas Melchior,Ole Nyvad,Morten Schou,Alain Boye,Didier Cadinot,Didier Gouet,Patrick Henry,Laurence Kessler,Jean-Daniel Lalau,Catherine Petit,Jean-Francois Thuan,Christel Voinot,Julien Vouillarmet,Christoph Axthelm,Dirk Berger,Tasso Bieler,Andreas L. Birkenfeld,Jochen Bott,Klaus Busch,Karel Caca,Julia Chevts,Torsten Donaubauer,Rudolf Erlinger,Klaus Funke,Josef Grosskopf,Andreas Hagenow,Monika Hamann,Manfred Hartard,Peter Heymer,Wolfgang Huppertz,Gabriele Illies,Stephan Jacob,Thomas Jung,Gerd Kahrmann,Petra Kast,Monika Kellerer,Hans-Peter Kempe,Andrei Khariouzov,Gerhard Klausmann,Christiane Klein,Uwe Kleinecke-Pohl,Klaus Kleinertz,Thorsten Koch,Christine Kosch,Babette Lorra,Joerg Luedemann,Matthias Luttermann,Stephan Maxeiner,Karsten Milek,Andrea Moelle,Gerhard Neumann,Ruth Nischik,Edith Oehrig-Pohl,Georg Plassmann,Lars Pohlmeier,Felix Proepper,Stefan Regner,Werner Rieker,Ludger Rose,Holger Samer,Joachim Sauter,Frank Schaper,Clemens Schiffer,Juergen Schmidt,Bernd-M. Scholz,Joerg Schulze,Alexander Segner,Jochen Seufert,Helena Sigal,Joerg Steindorf,Juergen Stockhausen,Petra Stuebler,Heidrun Taeschner,Dietrich Tews,Diethelm Tschoepe,Karl Wilhelm,Helga Zeller-Stefan,Iakovos Avramidis,Stavros Bousboulas,Magdalini Bristianou,Georgios Dimitriadis,Moses Elisaf,Kalliopi Kotsa,Andreas Melidonis,Asimina Mitrakou,Emmanouil Pagkalos,Nikolaos Papanas,A. Pappas,Christos Sampanis,Nikolaos Tentolouris,Apostolos Tsapas,Glykeria Tzatzagou,Risa Ozaki,Csaba Hajdú,Eleonóra Harcsa,Laszlo Konyves,János Mucsi,Zsolt Pauker,Gizella Petró,Zsolt Plés,Katalin Revesz,Vangel Sándor,Viktor Vass,Angelo Avogaro,Massimo Boemi,Riccardo C. Bonadonna,Agostino Consoli,Salvatore De Cosmo,Paolo Di Bartolo,Francesco Dotta,Simona Frontoni,Marianna Galetta,Alessandra Gambineri,Carmine Gazzaruso,Francesco Giorgino,Davide Lauro,Emanuela Orsi,Giuseppe Paolisso,Gabriele Perriello,PierMarco Piatti,Antonio E. Pontiroli,Paola Ponzani,Angela A. Rivellese,Giorgio Sesti,Giancarlo Tonolo,Roberto Trevisan,Chul Woo Ahn,Sei Hyun Baik,Bong Soo Cha,Choon Hee Chung,Hak Chul Jang,Chong-Jin Kim,Hye Soon Kim,In Joo Kim,Eun Young Lee,Hyoung Woo Lee,Kwan Woo Lee,Keon-Woong Moon,June Namgung,Kyong Soo Park,Soon Jib Yoo,Jaemyung Yu,Edmundo-Alfredo Bayram Llamas,Jose-Luis Cervantes-Escárcega,Luis Fernando Flota-Cervera,José Gerardo González-González,Sara Pascoe-Gonzalez,Emilia Susana Pelayo-Orozco,Santiago-Paulino Ramirez-Diaz,Arturo Saldana-Mendoza,Carlos Sánchez Jerjes-Díaz,Jose Juan Torres-Colores,Maricela Vidrio-Velázquez,Juan Villagordoa-Mesa,Hugo Peter Beijerbacht,Reginald G.E.J. Groutars,Boudewijn A Hoek,Pieter A.M. Hoogslag,Adriaan Kooy,Johannes A. Kragten,Aloysius G. Lieverse,Hendrik P. Swart,Eric P. Viergever,Jørn Ahlqvist,John G. Cooper,Hanne L. Gulseth,Gaute Guttormsen,Cecilie Wium,Hugo Arbañil,Jorge Calderon,L.M. Camacho,Augusto Dextre Espinoza,Elizabeth Garrido,Alejandro Luna,Helard Manrique,Frederick Massucco Revoredo,Rolando J Vargas Gonzales,Luis Zapata Rincon,Carlos Zubiate,Geraldine Ebo,Ellen Morales-Palomares,Malgorzata Arciszewska,Marek Banach,Renata Bijata-Bronisz,Tadeusz Derezinski,Waldemar Gadzinski,Jacek Gajek,Katarzyna Klodawska,Ewa Krzyzagorska,Andrzej Madej,Pawel Miekus,Jaroslaw Opiela,Piotr Romanczuk,Anna Siegel,Ewa Skokowska,Andrzej W Stankiewicz,Teresa Stasinska,Iwona Trznadel-Morawska,Robert Witek,Sergey Aksentyev,Irina A. Bondar,Irina Demidova,Alexander Dreval,Olga Ershova,Gagik R Galstyan,A. A. Garganeeva,Nadezhda Izmozherova,Victoria Karetnikova,Marina Kharakhulakh,Aleksandr Khokhlov,Zhanna Kobalava,Olga Koshelskaya,E. D. Kosmacheva,Vladimir Kostin,Natalia Koziolova,Anatoly Kuzin,Victor Lesnov,Tatyana Lysenko,Valentin Markov,Alexander Mayorov,Sergey Moiseev,Svetlana Myasoedova,Nina Petunina,A P Rebrov,Ludmila Aleksandrovna Ruyatkina,Julia Samoylova,Olga V. Sazonova,Natalia Shilkina,Nadezhda Sokolova,Olga Vasilevskaya,Nelli Verbovaya,Elena Vishneva,Sergey Vorobyev,Natalya Vorokhobina,Olga Zanozina,Elena Zhdanova,Tatyana Zykova,Lesley J. Burgess,Kathleen Coetzee,Saleem Dawood,Landman Lombard,Ellen Makoali Makotoko,Rajendran Moodley,Wessels Oosthuysen,Mohamed Sarvan,Carlos Calvo Gómez,Isidoro Cano Rodríguez,Almudena Castro Conde,Angel R Cequier Fillat,Guillem Cuatrecasas Cambra,Fernando de Álvaro Moreno,Luis De Teresa Parreno,Javier Delgado Lista,José Ramón Domínguez Escribano,Santiago Durán García,Javier Elvira González,José María Fernández Rodríguez,Alberto Goday Arno,Ricardo Gomez Huelgas,José Ramón González Juanatey,Antonio Hernandez Mijares,Víctor Alfonso Jiménez Díaz,Esteban Jodar Gimeno,Tomás Lucas Morante,Mónica Marazuela,Nieves Martell Claros,Didac Mauricio Puente,Elena Mena Ribas,Juan Francisco Merino Torres,Pedro Mezquita Raya,Andreu Nubiola Calonge,Xavier Ordoñez Sánchez,Jose Maria Pascual Izuel,Verónica Perea Castilla,Antonio Pérez Pérez,Isabel Perez Soto,Miguel Quesada Charneco,Angustias Quesada Simón,Josep Redón Mas,Antonia Rego Iraeta,Maria Rodriguez Alvarez,Irene Rodríguez Rodríguez,José Sabán Ruiz,Alfonso Soto Gonzalez,Francisco J Tinahones Madueno,Carlos Trescoli Serrano,Angels Ulied Armiñana,Erasmus Bachus,Katarina Berndtsson Blom,Ken Eliasson,Pekka Koskinen,Hans Larnefeldt,Cornelia Lif-Tiberg,Carina Linderfalk,Gustav Lund,Pia Lundman,Linda Moris,Åke Olsson,Staffan Salmonsson,Johan Sanmartin Berglund,Folke Sjöberg,Stefan Söderberg,Ingemar Torstensson,Jung-Fu Chen,Kai Jen Tien,Shih-Ting Tseng,Shih-Te Tu,Chih-Yuan Wang,Ji-Hung Wang,Arintaya Phrommintikul,Sukit Yamwong,Woravut Jintapakorn,Pisit Hutayanon,Nakarin Sansanayudh,Larysa Bazhan,Ivan Fushtey,Mariya Grachova,Vitaliy Katerenchuk,Vadym Korpachev,Nonna Kravchun,Oleksandr Larin,Galyna Mykhalchyshyn,Halyna Myshanych,Olga Oleksyk,Valeriia Orlenko,Nataliia Pashkovska,Nataliia Pertseva,Olena Petrosyan,Ivan Smirnov,Maryna Vlasenko,Tetiana Zlova,Myint Aye,Arun Baksi,Mathangi Balasubramani,Ronnie Beboso,Mark Blagden,Charles Bundy,Tobias Cookson,Allan Copland,Alistair Emslie-Smith,Fiona Green,Anthony Gunstone,Basil Issa,Ewart Jackson-Voyzey,Andrew C. Johnson,Malcolm Maclean,John McKnight,Solomon Muzulu,Ian O'Connell,Babatunde Oyesile,Catherine Patterson,Ewan R. Pearson,Sam Philip,Paul Smith,Usha Sukumaran,Jalal Abbas,Gaurav Aggarwala,Faiq Akhter,James L. Andersen,Moise Anglade,Georges Argoud,Mehrdad Ariani,Reswan Ashdji,Ladan Bakhtari,Subhash Banerjee,Andrew Bartlett,Howard Baum,Harold Bays,Richard Beasley,Renata Belfort de Aguiar,Sabrina Benjamin,Ravi Bhagwat,Anuj Bhargava,Bruce W. Bode,Christina Bratcher,Toby Briskin,Andrew Peter Brockmyre,Raymond Broughton,Judith Brown,Madhusudan Budhraja,Kevin Cannon,Jewell Carr,Harold Cathcart,Arvind Cavale,Louis B Chaykin,Deanna Cheung,Richard Childress,Allan Cohen,Jonathan Condit,Erin Cooksey,George Mitchell Cornett,Ira Dauber,William Davila,Luis De Armas,Julius Dean,Robert Detweiler,Ernesto Diaz,Michael Di Giovanna,Isaac Dor,Waymon Drummond,Donald Eagerton,John Earl,Charles B. Eaton,Howard Ellison,Neil Farris,Thomas Fiel,Anthony Firek,Brian First,Les Forgosh,William J. French,Winston Gandy,Ronald Garcia,Santosh Gill,Murray Gordon,Michael Guice,Siva Gummadi,Jonathan Hackenyos,Kristen Hairston,Lenita Hanson,Lindsay Harrison,Israel Hartman,John F. Heitner,Srini Hejeebu,Paul Hermany,Carlos Hernandez-Cassis,Horacio Hidalgo,Alexander Higgins,Hassan Ibrahim,Shahram Jacobs,David W. Johnson,Parag H. Joshi,Steven Richard Kaster,Daniel Kellum,Christopher Kim,Ellen Kim,William Kirby,Albert B Knouse,Steven Kulback,Mariananda Kumar,Tulsidas Kuruvanka,A. Labroo,William Lasswell,John Lentz,Thomas Lenzmeier,David Lewis,Zhaoping Li,Michael Lillestol,Raymond Little,Richard Lorraine,Cecilia McKeown-Biagas,Robert McNeill,Anand Mehta,Alan B. Miller,Joseph Moran,Emily Morawski,Venkatesh Nadar,Thomas G. O'Connor,Alberto Odio,Reginald Parker,Rajesh Patel,Lawrence S. Phillips,George Raad,Aref Rahman,Marina Raikhel,Ajit Raisinghani,Raj Rajan,Neda Rasouli,Frank Rauzi,Kathryn Rohr,Hal Roseman,Sergio Rovner,Fadi Saba,Richard Sachson,Alex Schabauer,Ricky Schneider,Timothy Schuchard,John Sensenbrenner,Yshay Shlesinger,Narendra Singh,Kanagaratnam Sivalingam,Larry D Stonesifer,Daniel Storey,David Suh,Mohammed Tahir,Anjanette Tan,Marilyn Tan,Alain Taylon,Maitreya Thakkar,Devjit Tripathy,Gabriel I. Uwaifo,Amarnath Vedere,Chandra Venugopal,Anthony Vo,Michelle Welch,James Welker,Alexander White,John Willis,Alan G Wynne,Shahram Yazdani,Anne Rosenberg,Lauren Price,Kristina N. Sigmon,Yuliya Lokhngina,Weibing Xing,Robert Overton,M.W. Stewart,Janet Stead,Alistair C. Lindsay,Vickas Patel,Jorge Ross,Joseph Soffer,Shruti Daga,Margaret Sowell,Prashant Patel,Louisa Garvey,Jessica Ackert,Sybil Abraham,Mary Beth Sabol,Desma Altobelli,JuYoung Ha,Mangesh Kulkarni,Matthew Somerville,Drusilla Noronha,Ed Casson,Eddie Zang,Chamandeep Sandhu,Rakesh Kumar,David Chen,Lin Taft,Rajivkumar Patel,June Ye,Jennifer Shannon,Tim Wilson,Charleen Babi,Diane Miller,Karl Thorpe,Rachael Russell,Georgina Bull,Belinda Hereghty,Eva Fernandez-Salazar,Troy Longley,Jill Donaldson,Marie Jarosz,Karen Murphy,Patricia A. Adams,Peter K. Smith,Rachel James,Jackie Richards,Sangeeta Sedani,Denise Althouse,David I. Watson,Jamie Lorimer,Steven Lauder,Ron Schultheis,Terese Womer,Ella Wraight,Wenyan Li,Emma Price-Olsen,Anthony W. Watson,Aoife Kelly,Patricia McLaughlin,John Fleming,Jessica Schubert,Debra Schleiden,Tara Harris,Rahul Prakash,Jody Breneman,Sameer Deshpande,Aarti Saswadkar,Aditi Kumari,Aditi Shitut,Amruta Raorane,Anisha Karmalkar,Ankita Mhambrey,Archana Bhosale,Ashok Vaphare,Ashwini P Patil,Chaitali Khandelwal,Fayaz Shaik,Madhumitha Nadar,Mounika Karka,Neha Kadgaonkar,Nikita Gupta,Nutan Aher,Omkar Potnis,Pallavi Naicker,Rakesh Shinde,Richa Sharma,Rupali Godse,Sheetal Solanki,Shruti Sahu,Snehal Dumbre,Somesh Kumar,Suradnya Patil,Trisha Mandal +798 more
TL;DR: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events, and evidence-based glucagon-like peptide 1 receptor agonists should be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events.