J
Jennifer Dackor
Researcher at University of North Carolina at Chapel Hill
Publications - 9
Citations - 1699
Jennifer Dackor is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Epidermal growth factor receptor & Body mass index. The author has an hindex of 8, co-authored 9 publications receiving 1601 citations. Previous affiliations of Jennifer Dackor include Research Triangle Park.
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Journal ArticleDOI
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Helena Furberg,Yunjung Kim,Jennifer Dackor,Eric Boerwinkle,Nora Franceschini,Diego Ardissino,Luisa Bernardinelli,Luisa Bernardinelli,Pier Mannuccio Mannucci,Francesco Mauri,Piera Angelica Merlini,Devin Absher,Themistocles L. Assimes,Stephen P. Fortmann,Carlos Iribarren,Joshua W. Knowles,Thomas Quertermous,Luigi Ferrucci,Toshiko Tanaka,Joshua C. Bis,Curt D. Furberg,Talin Haritunians,Barbara McKnight,Bruce M. Psaty,Bruce M. Psaty,Kent D. Taylor,Evan L. Thacker,Peter Almgren,Leif Groop,Claes Ladenvall,Michael Boehnke,Anne U. Jackson,Karen L. Mohlke,Heather M. Stringham,Jaakko Tuomilehto,Jaakko Tuomilehto,Emelia J. Benjamin,Shih-Jen Hwang,Daniel Levy,Sarah R. Preis,Ramachandran S. Vasan,Jubao Duan,Pablo V. Gejman,Douglas F. Levinson,Alan R. Sanders,Jianxin Shi,Esther H. Lips,James McKay,Antonio Agudo,Luigi Barzan,Vladimir Bencko,Simone Benhamou,Simone Benhamou,Xavier Castellsagué,Cristina Canova,David I. Conway,Eleonora Fabianova,Lenka Foretova,Vladimir Janout,Claire M. Healy,Ivana Holcatova,Kristina Kjærheim,Pagona Lagiou,Jolanta Lissowska,Ray Lowry,Tatiana V. Macfarlane,Dana Mates,Lorenzo Richiardi,Peter Rudnai,Neonilia Szeszenia-Dabrowska,David Zaridze,Ariana Znaor,Mark Lathrop,Paul Brennan,Stefania Bandinelli,Timothy M. Frayling,Jack M. Guralnik,Yuri Milaneschi,John R. B. Perry,David Altshuler,David Altshuler,Roberto Elosua,S. Kathiresan,S. Kathiresan,Gavin Lucas,Olle Melander,Christopher J. O'Donnell,Veikko Salomaa,Stephen M. Schwartz,Benjamin F. Voight,Brenda W.J.H. Penninx,Johannes H. Smit,Nicole Vogelzangs,Dorret I. Boomsma,Eco J. C. de Geus,Jacqueline M. Vink,Gonneke Willemsen,Stephen J. Chanock,Fangyi Gu,Susan E. Hankinson,David J. Hunter,Albert Hofman,Henning Tiemeier,André G. Uitterlinden,Cornelia M. van Duijn,Stefan Walter,Daniel I. Chasman,Brendan M. Everett,Guillaume Paré,Paul M. Ridker,Ming D. Li,Hermine H. Maes,Janet Audrain-McGovern,Danielle Posthuma,Laura M. Thornton,Caryn Lerman,Jaakko Kaprio,Jaakko Kaprio,Jed E. Rose,John P. A. Ioannidis,John P. A. Ioannidis,Peter Kraft,Danyu Lin,Patrick F. Sullivan +123 more
TL;DR: A meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium found the strongest association was a synonymous 15q25 SNP in the nicotinic receptor gene CHRNA3, and three loci associated with number of cigarettes smoked per day were identified.
A genome-wide association study of anorexia nervosa
Vesna Boraska,Christopher S. Franklin,James A B Floyd,Laura M. Thornton,Laura M. Huckins,L. Southam,Nigel W. Rayner,Ioanna Tachmazidou,Kelly L. Klump,Janet Treasure,Cathryn M. Lewis,Ulrike Schmidt,Federica Tozzi,Kirsty Kiezebrink,Johannes Hebebrand,Philip Gorwood,Roger A.H. Adan,Martien J H Kas,Angela Favaro,Paolo Santonastaso,Fernando Fernández-Aranda,Mònica Gratacòs,Filip Rybakowski,Monika Dmitrzak-Weglarz,Jaakko Kaprio,Anna Keski-Rahkonen,Anu Raevuori,E. F. van Furth,M. C. T. Slof-Op 't Landt,James I. Hudson,Ted Reichborn-Kjennerud,Gun Peggy Knudsen,Palmiero Monteleone,Allan S. Kaplan,Andreas Karwautz,Hakon Hakonarson,Wade H. Berrettini,Yiran Guo,Dong Li,Nicholas J. Schork,Gen Komaki,Tetsuya Ando,Hidetoshi Inoko,Tõnu Esko,K. Fischer,K. Maennik,Andres Metspalu,Jessica H. Baker,Roger D. Cone,Jennifer Dackor,Janiece E. DeSocio,Chris Hilliard,Julie K. O'Toole,Johannes Pantel,Jin P. Szatkiewicz,C. Taico,Stephanie Zerwas,Sara E. Trace,Oliver S. P. Davis,Sietske G. Helder,Katharina Buehren,Roland Burghardt,M. de Zwaan,Karin Egberts,Stefan Ehrlich,Beate Herpertz-Dahlmann,Wolfgang Herzog,Hartmut Imgart,André Scherag,S. Scherag,Stephan Zipfel,Claudette Boni,Nicolas Ramoz,Audrey Versini,Marek K. Brandys,Unna N. Danner,C. G. F. de Kovel,Judith Hendriks,B. P. C. Koeleman,Roel A. Ophoff,Eric Strengman,A. A. van Elburg,Alice Bruson,Maurizio Clementi,Daniela Degortes,Monica Forzan,Elena Tenconi,Elisa Docampo,Geòrgia Escaramís,Susana Jiménez-Murcia,Jolanta Lissowska,Andrzej Rajewski,Neonilia Szeszenia-Dabrowska,Agnieszka Słopień,Joanna Hauser,Leila Karhunen,Ingrid Meulenbelt,P.E. Slagboom,Alfonso Tortorella,Mario Maj,George Dedoussis,Dimitris Dikeos,Fragiskos Gonidakis,Konstantinos Tziouvas,Artemis Tsitsika,Hana Papezova,L. Slachtova,D. Martaskova,James L. Kennedy,Robert D. Levitan,Zeynep Yilmaz,Julia Huemer,Doris Koubek,Elisabeth Merl,Günter P. Wagner,Paul Lichtenstein,Gerome Breen,Sarah Cohen-Woods,Anne Farmer,Peter McGuffin,Sven Cichon,Ina Giegling,Stefan Herms,Dan Rujescu,Stefan Schreiber,H-E Wichmann,Christian Dina,Robert Sladek,Giovanni Gambaro,Nicole Soranzo,Antonio Julià,Sara Marsal,Raquel Rabionet,Valerie Gaborieau,Danielle M. Dick,Aarno Palotie,Samuli Ripatti,Elisabeth Widen,Ole A. Andreassen,Thomas Espeseth,Astri J. Lundervold,Ivar Reinvang,Vidar M. Steen,S. Le Hellard,Morten Mattingsdal,Ioanna Ntalla,Vladimir Bencko,Lenka Foretová,Vladimir Janout,Marie Navratilova,S. Gallinger,Dalila Pinto,Stephen W. Scherer,Harald N. Aschauer,Laura Carlberg,Alexandra Schosser,Lars Alfredsson,Bo Ding,Lars Klareskog,Leonid Padyukov,Philippe Courtet,Sébastien Guillaume,Isabelle Jaussent,Chris Finan,Gursharan Kalsi,Marion Roberts,Darren W. Logan,Leena Peltonen,Graham R S Ritchie,Jeffrey C. Barrett,Xavier Estivill,Anke Hinney,Patrick F. Sullivan,David A. Collier,Eleftheria Zeggini,Cynthia M. Bulik +175 more
TL;DR: The accrual of large genotyped AN case-control samples should be an immediate priority for the field, suggesting that true findings exist but the sample, the largest yet reported, was underpowered for their detection.
Journal ArticleDOI
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
Nobukazu Fujimoto,Nobukazu Fujimoto,Marie Wislez,Marie Wislez,Marie Wislez,Jie Zhang,Kentaro Iwanaga,Jennifer Dackor,Amy E. Hanna,Shailaja Kalyankrishna,Dianna D. Cody,Roger E. Price,Mitsuo Sato,Jerry W. Shay,John D. Minna,Michael Peyton,Ximing Tang,Erminia Massarelli,Roy S. Herbst,David W. Threadgill,Ignacio I. Wistuba,Jonathan M. Kurie +21 more
TL;DR: Lung adenocarcinoma cells that depend on EGFR for survival constitutively activate the receptor through a combination of genetic mutations and overexpression of EGFR dimeric partners and their ligands.
Journal ArticleDOI
A common biological basis of obesity and nicotine addiction
Thorgeir E. Thorgeirsson,Daniel F. Gudbjartsson,Patrick Sulem,Søren Besenbacher,Søren Besenbacher,Unnur Styrkarsdottir,Gudmar Thorleifsson,G B Walters,Helena Furberg,Patrick F. Sullivan,Jonathan Marchini,Jonathan Marchini,Mark I. McCarthy,Mark I. McCarthy,Valgerdur Steinthorsdottir,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Ida Surakka,Ida Surakka,Jacqueline M. Vink,Najaf Amin,Frank Geller,Thorunn Rafnar,Tõnu Esko,Tõnu Esko,Stefan Walter,Christian Gieger,Rajesh Rawal,Massimo Mangino,Inga Prokopenko,Inga Prokopenko,Reedik Mägi,Reedik Mägi,Reedik Mägi,Kaisu Keskitalo,Iris H Gudjonsdottir,Solveig Gretarsdottir,Hreinn Stefansson,Yurii S. Aulchenko,Mari Nelis,Mari Nelis,Katja K.H. Aben,Martin den Heijer,Nicole Soranzo,Nicole Soranzo,Ana M. Valdes,Claire J. Steves,André G. Uitterlinden,Albert Hofman,Anke Tönjes,Peter Kovacs,Jouke-Jan Hottenga,Gonneke Willemsen,Nicole Vogelzangs,Angela Döring,Norbert Dahmen,Norbert Dahmen,Barbara Nitz,Samuli Ripatti,Samuli Ripatti,M. Perola,M. Perola,Johannes Kettunen,Anna-Liisa Hartikainen,Anna-Liisa Hartikainen,Anneli Pouta,Jaana Laitinen,Matti Isohanni,Matti Isohanni,Shen Huei-Yi,Shen Huei-Yi,Maxine Allen,Maria Krestyaninova,Alistair S. Hall,John R. Thompson,Hogni Oskarsson,Thorarinn Tyrfingsson,Lambertus A. Kiemeney,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Veikko Salomaa,Michael Stumvoll,Tim D. Spector,H.-Erich Wichmann,Andres Metspalu,Andres Metspalu,Nilesh J. Samani,Brenda W.J.H. Penninx,Ben A. Oostra,Dorret I. Boomsma,Henning Tiemeier,Cornelia M. van Duijn,Jaakko Kaprio,Jaakko Kaprio,Jeffrey R. Gulcher,Yunjung Kim,Jennifer Dackor,Eric Boerwinkle,Nora Franceschini,Diego Ardissino,Luisa Bernardinelli,Luisa Bernardinelli,Pier Mannuccio Mannucci,Francesco Mauri,Piera Angelica Merlini,Devin Absher,Themistocles L. Assimes,Stephen P. Fortmann,Carlos Iribarren,Joshua W. Knowles,Thomas Quertermous,Luigi Ferrucci,Toshiko Tanaka,Joshua C. Bis,Curt D. Furberg,Talin Haritunians,Barbara McKnight,Bruce M. Psaty,Bruce M. Psaty,Kent D. Taylor,Evan L. Thacker,Peter Almgren,Leif Groop,Claes Ladenvall,Michael Boehnke,Anne U. Jackson,Karen L. Mohlke,Heather M. Stringham,Jaakko Tuomilehto,Jaakko Tuomilehto,Emelia J. Benjamin,Shih-Jen Hwang,Daniel Levy,Sarah R. Preis,Ramachandran S. Vasan,Jubao Duan,Pablo V. Gejman,Douglas F. Levinson,Alan R. Sanders,Jianxin Shi,Esther H. Lips,James McKay,Antonio Agudo,Luigi Barzan,Vladimir Bencko,Simone Benhamou,Xavier Castellsagué,Cristina Canova,David I. Conway,Eleonora Fabianova,Lenka Foretova,Vladimir Janout,Claire M. Healy,Ivana Holcatova,Kristina Kjærheim,Pagona Lagiou,Jolanta Lissowska,Ray Lowry,Tatiana V. Macfarlane,Dana Mates,Lorenzo Richiardi,Peter Rudnai,Neonilia Szeszenia-Dabrowska,David Zaridze,Ariana Znaor,Mark Lathrop,Mark Lathrop,Paul Brennan,Stefania Bandinelli,Timothy M. Frayling,Jack M. Guralnik,Yuri Milaneschi,John R. B. Perry,David Altshuler,David Altshuler,Roberto Elosua,S. Kathiresan,S. Kathiresan,Gavin Lucas,Olle Melander,Christopher J. O'Donnell,Stephen M. Schwartz,Benjamin F. Voight,Benjamin F. Voight,Johannes H. Smit,Johannes H. Smit,Eco J. C. de Geus,Stephen J. Chanock,Stephen J. Chanock,Fangyi Gu,Fangyi Gu,Susan E. Hankinson,David J. Hunter,David J. Hunter,Daniel I. Chasman,Brendan M. Everett,Brendan M. Everett,Brendan M. Everett,Guillaume Paré,Guillaume Paré,Paul M. Ridker,Ming D. Li,Hermine H. Maes,Janet Audrain-McGovern,Danielle Posthuma,Laura M. Thornton,Caryn Lerman,Jed E. Rose,John P. A. Ioannidis,John P. A. Ioannidis,Peter Kraft,Danyu Lin,Danyu Lin,Jason S. Liu,Federica Tozzi,Dawn M. Waterworth,Sreekumar G. Pillai,Pierandrea Muglia,Lefkos T. Middleton,Wade H. Berrettini,Christopher W. Knouff,Xin Yuan,Gérard Waeber,Peter Vollenweider,Martin Preisig,Nicholas J. Wareham,Jing Hua Zhao,Ruth J. F. Loos,Inês Barroso,Kay-Tee Khaw,Scott M. Grundy,Philip J. Barter,Robert W. Mahley,Antero Kesäniemi,Ruth McPherson,Ruth McPherson,John B. Vincent,John Strauss,James L. Kennedy,Anne Farmer,Peter McGuffin,Richard O. Day,Keith Matthews,Per Bakke,Amund Gulsvik,Susanne Lucae,Marcus Ising,T. Brueckl,S. Horstmann,Joachim Heinrich,Claudia Lamina,Claudia Lamina,Ozren Polasek,Lina Zgaga,Jennifer E. Huffman,Susan Campbell,Jaspal S. Kooner,John C. Chambers,Mary Susan Burnett,Joe Devaney,Augusto D. Pichard,Kenneth M. Kent,Lowell F. Satler,Joseph M. Lindsay,Ron Waksman,Stephen E. Epstein,James F. Wilson,Sarah H. Wild,Harry Campbell,Veronique Vitart,Muredach P. Reilly,Mingyao Li,Liming Qu,Robert L. Wilensky,William H. Matthai,Hakon Hakonarson,Daniel J. Rader,Andre Franke,Michael Wittig,Arne Schäfer,Manuela Uda,Antonio Terracciano,Xiangjun Xiao,Fabio Busonero,Paul Scheet,David Schlessinger,David St Clair,Dan Rujescu,Gonçalo R. Abecasis,Hans J. Grabe,Alexander Teumer,Henry Völzke,Astrid Petersmann,Ulrich John,Igor Rudan,Caroline Hayward,Alan F. Wright,Ivana Kolcic,Benjamin J. Wright,Anthony J. Balmforth,Carl A. Anderson,Tariq Ahmed,Christopher G. Mathew,Miles Parkes,Jack Satsangi,Mark J. Caulfield,Patricia B. Munroe,Martin Farrall,Anna F. Dominiczak,Jane Worthington,Wendy Thomson,Steve Eyre,Anne Barton,Vincent Mooser,Clyde Francks +316 more
TL;DR: The results strongly point to a common biological basis of the regulation of theregulation of the authors' appetite for tobacco and food, and thus the vulnerability to nicotine addiction and obesity, and the effect of single-nucleotide polymorphisms affecting body mass index (BMI).
Journal ArticleDOI
Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles
TL;DR: It is suggested that Egfrwa2 homozygous embryos model EGFR-mediated intrauterine growth restriction in humans and differential expression in the placenta of Glut3, a glucose transporter essential for normal embryonic growth, may contribute to strain-dependent differences in intrauterne growth restriction caused by reduced EGFR activity.