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Shannon L. Risacher
Researcher at Indiana University
Publications - 288
Citations - 12478
Shannon L. Risacher is an academic researcher from Indiana University. The author has contributed to research in topics: Cognition & Medicine. The author has an hindex of 51, co-authored 246 publications receiving 9808 citations. Previous affiliations of Shannon L. Risacher include Indiana University – Purdue University Indianapolis & University of Texas at Arlington.
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Journal ArticleDOI
White matter alterations in early-stage Alzheimer's disease: A tract-specific study
Qiuting Wen,Sourajit M. Mustafi,Junjie Li,Shannon L. Risacher,Eileen F. Tallman,Steven A. Brown,John D. West,Jaroslaw Harezlak,Martin R. Farlow,Frederick W. Unverzagt,Sujuan Gao,Liana G. Apostolova,Andrew J. Saykin,Yu-Chien Wu +13 more
TL;DR: Diffusion magnetic resonance imaging may allow for microscopic characterization of white matter degeneration in early stages of Alzheimer's disease.
Journal ArticleDOI
Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease.
Kacie D Deters,Shannon L. Risacher,Sungeun Kim,Sungeun Kim,Kwangsik Nho,John D. West,Kaj Blennow,Henrik Zetterberg,Henrik Zetterberg,Leslie M. Shaw,John Q. Trojanowski,Michael W. Weiner,Andrew J. Saykin +12 more
TL;DR: Plasma tau may serve as a non-specific marker for neurodegeneration but is still relevant to AD considering low GMD was associated with plasma tau in Aβ+ participants and not Aβ-participants.
Journal ArticleDOI
Association of cancer history with Alzheimer's disease onset and structural brain changes
Kelly N.H. Nudelman,Shannon L. Risacher,John D. West,Brenna C. McDonald,Sujuan Gao,Andrew J. Saykin +5 more
TL;DR: While cancer history is associated with a measurable delay in AD onset independent of APOE ε4, the underlying mechanism does not appear to be cancer-related preservation of GMD.
Posted ContentDOI
The genetic architecture of the human cerebral cortex
Katrina L. Grasby,Neda Jahanshad,Jodie N. Painter,Lucía Colodro-Conde,Janita Bralten,Derrek P. Hibar,Derrek P. Hibar,Penelope A. Lind,Fabrizio Pizzagalli,Christopher R.K. Ching,Christopher R.K. Ching,Mary Agnes McMahon,Natalia Shatokhina,Leo Charles Peek Zsembik,Ingrid Agartz,Saud Alhusaini,Saud Alhusaini,Marcio Almeida,Dag Alnæs,Dag Alnæs,Inge K Amlien,Micael Andersson,Tyler Ard,Nicola J. Armstrong,Allison E. Ashley-Koch,Joshua R. Atkins,Manon Bernard,Rachel M. Brouwer,Elizabeth E.L. Buimer,Robin Bülow,Christian Bürger,Dara M. Cannon,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Joshua W. Cheung,Baptiste Couvy-Duchesne,Baptiste Couvy-Duchesne,Anders M. Dale,Anders M. Dale,Shareefa Dalvie,Tânia Kawasaki de Araujo,Greig I. de Zubicaray,Sonja M C de Zwarte,Anouk den Braber,Nhat Trung Doan,Nhat Trung Doan,Katharina Dohm,Stefan Ehrlich,Hannah-Ruth Engelbrecht,Susanne Erk,Chun Chieh Fan,Iryna O. Fedko,Sonya Foley,Judith M. Ford,Masaki Fukunaga,Melanie E. Garrett,Tian Ge,Sudheer Giddaluru,Aaron L. Goldman,Melissa J. Green,Melissa J. Green,Nynke A. Groenewold,Dominik Grotegerd,Tiril P. Gurholt,Tiril P. Gurholt,Boris A. Gutman,Boris A. Gutman,Narelle K. Hansell,Mathew A. Harris,Marc B. Harrison,Courtney C. Haswell,Michael A. Hauser,Stefan Herms,Stefan Herms,Stefan Herms,Dirk J. Heslenfeld,New Fei Ho,D. Hoehn,Per Hoffmann,Per Hoffmann,Per Hoffmann,Laurena Holleran,Martine Hoogman,Jouke-Jan Hottenga,Masashi Ikeda,Deborah Janowitz,Iris E. Jansen,Tianye Jia,Tianye Jia,Christiane Jockwitz,Christiane Jockwitz,Ryota Kanai,Ryota Kanai,Sherif Karama,Sherif Karama,Sherif Karama,Dalia Kasperaviciute,Tobias Kaufmann,Tobias Kaufmann,Sinead Kelly,Sinead Kelly,Masataka Kikuchi,Marieke Klein,Marieke Klein,Michael Knapp,Annchen R. Knodt,Bernd Kramer,Bernd Kramer,Max Lam,Thomas M. Lancaster,Phil Lee,Tristram A. Lett,Lindsay B. Lewis,Lindsay B. Lewis,Iscia Lopes-Cendes,Michelle Luciano,Fabio Macciardi,Andre F. Marquand,Samuel R. Mathias,Tracy R. Melzer,Yuri Milaneschi,Nazanin Mirza-Schreiber,José C. V. Moreira,Thomas W. Mühleisen,Thomas W. Mühleisen,Thomas W. Mühleisen,Bertram Müller-Myhsok,Pablo Najt,Soichiro Nakahara,Soichiro Nakahara,Kwangsik Nho,Loes M. Olde Loohuis,Dimitri Papadopoulos Orfanos,John F. Pearson,Toni L. Pitcher,Benno Pütz,Yann Quidé,Yann Quidé,Anjanibhargavi Ragothaman,Faisal Rashid,William R. Reay,Ronny Redlich,Céline S. Reinbold,Céline S. Reinbold,Jonathan Repple,Geneviève Richard,Brandalyn C. Riedel,Brandalyn C. Riedel,Shannon L. Risacher,Cristiane S. Rocha,Nina Roth Mota,Lauren E. Salminen,Arvin Saremi,Andrew J. Saykin,Fenja Schlag,Lianne Schmaal,Lianne Schmaal,Peter R. Schofield,Peter R. Schofield,Rodrigo Secolin,Chin Yang Shapland,Li Shen,Jean Shin,Elena Shumskaya,Ida E Sønderby,Ida E Sønderby,Emma Sprooten,Lachlan T. Strike,Katherine E. Tansey,Alexander Teumer,Anbupalam Thalamuthu,Sophia I. Thomopoulos,Diana Tordesillas-Gutiérrez,Jessica A. Turner,Anne Uhlmann,Anne Uhlmann,Costanza L. Vallerga,Dennis van der Meer,Dennis van der Meer,Marjolein M. J. Van Donkelaar,Liza van Eijk,Theo G.M. van Erp,Neeltje E.M. van Haren,Neeltje E.M. van Haren,Daan van Rooij,Marie-José van Tol,Jan H. Veldink,Ellen Verhoef,Esther Walton,Esther Walton,Mingyuan Wang,Yunpeng Wang,Yunpeng Wang,Joanna M. Wardlaw,Wei Wen,Lars T. Westlye,Lars T. Westlye,Christopher D. Whelan,Christopher D. Whelan,Stephanie H. Witt,Katharina Wittfeld,Katharina Wittfeld,Christiane Wolf,Thomas Wolfers,Jing Qin Wu,Clarissa L. Yasuda,Dario Zaremba,Zuo Zhang,Alyssa H. Zhu,Marcel P. Zwiers,Eric Artiges,Amelia A. Assareh,Rosa Ayesa-Arriola,Aysenil Belger,Christine L. Brandt,Christine L. Brandt,Gregory G. Brown,Sven Cichon,Sven Cichon,Sven Cichon,Joanne E. Curran,Gareth E. Davies,Franziska Degenhardt,Michelle F. Dennis,Bruno Dietsche,Srdjan Djurovic,Srdjan Djurovic,Colin P. Doherty,Ryan Espiritu,Daniel Garijo,Yolanda Gil,Penny A. Gowland,Robert C. Green,Robert C. Green,Robert C. Green,Alexander N. Häusler,Alexander N. Häusler,Walter Heindel,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Florian Holsboer,Georg Homuth,Norbert Hosten,Clifford R. Jack,MiHyun Jang,Andreas Jansen,Nathan A. Kimbrel,Knut K. Kolskår,Sanne Koops,Axel Krug,Kelvin O. Lim,Jurjen J. Luykx,Daniel H. Mathalon,Daniel H. Mathalon,Karen A. Mather,Karen A. Mather,Venkata S. Mattay,Sarah Matthews,Jaqueline Mayoral Van Son,Sarah McEwen,Ingrid Melle,Ingrid Melle,Derek W. Morris,Bryon A. Mueller,Matthias Nauck,Jan Egil Nordvik,Markus M. Nöthen,Daniel S. O'Leary,Nils Opel,Marie-Laure Paillère Martinot,G. Bruce Pike,Adrian Preda,Erin Burke Quinlan,Paul E. Rasser,Varun Ratnakar,Simone Reppermund,Vidar M. Steen,Vidar M. Steen,Paul A. Tooney,Fábio R. Torres,Dick J. Veltman,James T. Voyvodic,Robert Whelan,Tonya White,Hidenaga Yamamori,Oscar L. Lopez,Hieab H.H. Adams,Joshua C. Bis,Stéphanie Debette,Charles DeCarli,Myriam Fornage,Vilmundur Gudnason,Edith Hofer,M. Arfan Ikram,Lenore J. Launer,William T. Longstreth,Bernard Mazoyer,Thomas H. Mosley,Gennady V. Roshchupkin,Claudia L. Satizabal,Claudia L. Satizabal,Reinhold Schmidt,Sudha Seshadri,Sudha Seshadri,Qiong Yang,Marina K. M. Alvim,David Ames,Tim J. Anderson,Ole A. Andreassen,Ole A. Andreassen,Alejandro Arias-Vasquez,Mark E. Bastin,Bernhard T. Baune,Bernhard T. Baune,John Blangero,Dorret I. Boomsma,Henry Brodaty,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Juan R. Bustillo,Wiepke Cahn,Murray J. Cairns,Vince D. Calhoun,Vaughan J. Carr,Vaughan J. Carr,Vaughan J. Carr,Xavier Caseras,Svenja Caspers,Svenja Caspers,Gianpiero L. Cavalleri,Fernando Cendes,Benedicto Crespo-Facorro,John C. Dalrymple-Alford,Udo Dannlowski,Eco J. C. de Geus,Ian J. Deary,Chantal Depondt,Sylvane Desrivières,Gary Donohoe,Thomas Espeseth,Thomas Espeseth,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Herta Flor,Andreas J. Forstner,Clyde Francks,Clyde Francks,Barbara Franke,David C. Glahn,Randy L. Gollub,Hans J. Grabe,Hans J. Grabe,Oliver Gruber,Asta Håberg,Ahmad R. Hariri,Catharina A. Hartman,Ryota Hashimoto,Andreas Heinz,Frans Henskens,Manon H.J. Hillegers,Manon H.J. Hillegers,Pieter J. Hoekstra,Avram J. Holmes,Avram J. Holmes,L. Elliot Hong,William D. Hopkins,William D. Hopkins,Hilleke E. Hulshoff Pol,Terry L. Jernigan,Erik G. Jönsson,Erik G. Jönsson,René S. Kahn,René S. Kahn,Martin A. Kennedy,Tilo Kircher,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,John B.J. Kwok,Stephanie Le Hellard,Stephanie Le Hellard,Carmel M. Loughland,Carmel M. Loughland,Nicholas G. Martin,Jean-Luc Martinot,Colm McDonald,Katie L. McMahon,Andreas Meyer-Lindenberg,Patricia T. Michie,Rajendra A. Morey,Bryan J. Mowry,Lars Nyberg,Jaap Oosterlaan,Jaap Oosterlaan,Roel A. Ophoff,Christos Pantelis,Tomáš Paus,Tomáš Paus,Zdenka Pausova,Brenda W.J.H. Penninx,Tinca J. C. Polderman,Danielle Posthuma,Marcella Rietschel,Joshua L. Roffman,Laura M. Rowland,Perminder S. Sachdev,Philipp G. Sämann,Ulrich Schall,Gunter Schumann,Rodney J. Scott,Rodney J. Scott,Kang Sim,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Iris E. C. Sommer,Beate St Pourcain,Beate St Pourcain,Beate St Pourcain,Dan J. Stein,Arthur W. Toga,Julian N. Trollor,Nic J.A. van der Wee,Dennis van 't Ent,Henry Völzke,Henrik Walter,Bernd Weber,Bernd Weber,Daniel R. Weinberger,Margaret J. Wright,Juan Zhou,Jason L. Stein,Paul M. Thompson,Sarah E. Medland +438 more
TL;DR: A genome-wide association meta-analysis of brain MRI data from 35,660 individuals with replication in 15,578 individuals found significant enrichment for loci influencing total surface area within regulatory elements active during prenatal cortical development, supporting the radial unit hypothesis.
Journal ArticleDOI
Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease.
Xiaoke Hao,Chanxiu Li,Lei Du,Xiaohui Yao,Jingwen Yan,Shannon L. Risacher,Andrew J. Saykin,Li Shen,Daoqiang Zhang +8 more
TL;DR: The proposed T-SCCA model not only outperforms the traditional SCCA method in terms of identifying strong associations, but also discovers robust outcome-relevant imaging genetic patterns, demonstrating its promise for improving disease-related mechanistic understanding.