S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Positive Selection Linked with Generation of Novel Mammalian Dentition Patterns.
João Paulo Machado,Siby Philip,Emanuel Maldonado,Stephen J. O'Brien,Warren E. Johnson,Agostinho Antunes +5 more
TL;DR: The results suggest that the evolution and development of mammalian dentition occurred in part through positive selection acting on genes that previously had other functions, as they have higher evolutionary rates and exhibit different expression profiles compared with older genes.
Journal ArticleDOI
Restoring tigers to the Caspian region.
Carlos A. Driscoll,Carlos A. Driscoll,Shu-Jin Luo,David W. Macdonald,Eric Dinerstein,Igor Chestin,Olga B. Pereladova,Stephen J. O'Brien +7 more
TL;DR: Efforts to save tigers in their native habitat are faring badly and it is clear that four of nine recognized tiger species are in danger of extinction.
Book ChapterDOI
What Is a Tiger? Genetics and Phylogeography
TL;DR: The evolutionary history framing the tiger into the exquisite predator has ancestral roots and history are depicted in its phylogeography, the genetic patterns of diversification among individuals and populations on both temporal and geographical scales.
Journal ArticleDOI
Subspecific Status of the Korean Tiger Inferred by Ancient DNA Analysis
Mu-Yeong Lee,Jee Yun Hyun,Seojin Stacey Lee,Junghwa An,Eun-Ok Lee,Mi-Sook Min,Junpei Kimura,Shin-ichirio Kawada,Nozomi Kurihara,Shu-Jin Luo,Stephen J. O'Brien,Warren E. Johnson,Hang Lee +12 more
TL;DR: The results support the conclusion that the Korean tiger should be classified as P. t.
Journal ArticleDOI
Identified OAS3 gene variants associated with coexistence of HBsAg and anti-HBs in chronic HBV infection.
Sa Wang,Jing Wang,Mengjie Fan,Tengyan Li,Hong Pan,Xi Wang,Hankui Liu,Qiongfen Lin,Jianguo Zhang,Liping Guan,Daria V. Zhernakova,Stephen J. O'Brien,Zhenru Feng,Le Chang,Erhei Dai,Jianhua Lu,Hong-Li Xi,Zheng Zeng,Yanyan Yu,Binbin Wang +19 more
TL;DR: Gene‐based burden analysis showed that protein‐coding rare variations on the OAS3 gene are associated with the coexistence of HBsAg and anti‐HBs in patients with chronic HBV infection in Chinese Han population.