S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
Papers
More filters
Journal ArticleDOI
Paper #107 Arthroscopic release of the long head of the biceps tendon: functional outcome and clinical results
TL;DR: It is concluded that the LHBT does not play a significant role in either the rotator cuff–deficient or normal shoulder, and an EMG analysis of the LH BT in 10 shoulders supported this finding.
Journal ArticleDOI
Tissue sampling methods and standards for vertebrate genomics.
Pamela By Wong,Pamela By Wong,Edward O. Wiley,Warren E. Johnson,Oliver A. Ryder,Stephen J. O'Brien,David Haussler,Klaus-Peter Koepfli,Marlys L. Houck,Polina L. Perelman,Gabriela F. Mastromonaco,Andrew Bentley,Byrappa Venkatesh,Ya-Ping Zhang,Ya-Ping Zhang,Robert W. Murphy,Robert W. Murphy,Robert W. Murphy,G Kcos +18 more
TL;DR: This work provides a legal and methodological guide according to four standards of acquiring and storing tissue for the Genome 10K Project and similar initiatives as follows: four-star (banked tissue/cell cultures, RNA from multiple types of tissue for transcriptomes, and sufficient flash-frozen tissue for 1 mg of DNA, all from a single individual).
Journal ArticleDOI
Patterns of ethnic diversity among the genes that influence AIDS
TL;DR: It is shown that the majority of AIDS candidate genes and AIDS restriction genes show significant differences in allele frequencies, possibly the result of historic selective pressures.
Journal ArticleDOI
Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism
Nicholas P. Anagnou,Stephen J. O'Brien,Takashi Shimada,William G. Nash,Mann-Jy Chen,Arthur W. Nienhuis +5 more
TL;DR: HDHFR-psi 1 was found to be present in DNA of some individuals and absent from DNA of others, consistent with a recent evolutionary origin of this gene originally suggested by its sequence identity to the coding portions of the functional gene.
Journal ArticleDOI
A Common HLA–DPA1 Variant is a Major Determinant of Hepatitis B Virus Clearance in Han Chinese
TL;DR: HLA - DPA1 rs3077 T was strongly associated with decreased risk of chronic HBV infection and it was showed for the first time to the knowledge that it is a predictor for HBV clearance, however,rs3077 was not associated with the development of cirrhosis or hepatocellular carcinoma.