S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Mammalian Genome Mapping: Lessons and Prospects
TL;DR: An empirical strategy for developing new gene maps in mammals by emphasizing two important classes of index or anchor marker loci is presented.
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Estimation of heterozygosity for single-probe multilocus DNA fingerprints.
TL;DR: The observations, as well as consideration of the effect of missing alleles and alternate numbers of loci, suggest that the average heterozygosity can be accurately estimated using phenotypic DNA fingerprint patterns, because this parameter is relatively insensitive to the lack of certain genetic information.
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Developing animal model systems for embryo technologies in rare and endangered wildlife
David E. Wildt,M.C. Schiewe,P.M. Schmidt,K. L. Goodrowe,JoGayle Howard,Lyndsay Phillips,Stephen J. O'Brien,M. Bush +7 more
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Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations.
Taras K. Oleksyk,Kai Zhao,Francisco M. De La Vega,Dennis A. Gilbert,Stephen J. O'Brien,Michael W. Smith +5 more
TL;DR: This study scanned an array of 31 different-sized moving windows of SNP variants across the human genome in a set of European and African American population samples with 183,997 SNP loci and revealed 180 regions of recent selection with very strong evidence in either population or both.
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A molecular phylogeny of the Felidae: immunological distance
TL;DR: The phylogenetic distances between 34 of the 37 extant species of Felidae were estimated using albumin immunological distances (AID) and the derived topology is highly consistent with the karyological disposition of these species, as well as with the fossil record of this family.