S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Mapping of PRM 1 to human chromosome 16 and tight linkage of Prm-1 and Prm-2 on mouse chromosome 16
Roger H. Reeves,John P. Gearhart,Norman B. Hecht,Pamela C. Yelick,Paula A. Johnson,Stephen J. O'Brien +5 more
TL;DR: The protamines are small, arginine-rich nuclear proteins that replace histones and transition proteins late in the haploid phase of spermatogenesis in mammals and are among a limited number of genes known to be expressed postmeiotically in male haploid germ cells.
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Influence of day of oestrus on egg viability and comparative efficiency of in vitro fertilization in domestic cats in natural or gonadotrophin-induced oestrus.
TL;DR: The proportion of eggs cleaving in vitro was similar between the natural oestrus group (48.3%) and the PMSG/hCG group (50.9%), but the latter group produced more than twice the number of embryos per donor.
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HLA-B Bw4 alleles and HIV-1 transmission in heterosexual couples
Tania M. Welzel,Xiaojiang Gao,Ruth M. Pfeiffer,Maureen P. Martin,Stephen J. O'Brien,James J. Goedert,Mary Carrington,Thomas R. O'Brien +7 more
TL;DR: The presence of HLA-Bw4 in HIV-1-infected men was associated with a decreased risk of male-to-female HIV-2 transmission, which suggests that these alleles reduce infectivity for HIV- 1.
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A Dog's Breakfast?
TL;DR: Even though the coverage of the dog genome (1.5x) is lower than that of mouse (8x), there are many valuable insights to be gained from comparing the sequence of dog with those of mouse and human.
Journal Article
Chromosomal localization and racial distribution of the polymorphic human dihydrofolate reductase pseudogene (DHFRP1).
Nicholas P. Anagnou,Stylianos E. Antonarakis,Stephen J. O'Brien,William S. Modi,Arthur W. Nienhuis +4 more
TL;DR: The racial distribution of the DHFRP1 pseudogene in five racial groups suggests that the transposition of this "perfect" pseudogene occurred prior to the inception of the human racial groups.