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Stephen J. O'Brien

Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics

Publications -  1074
Citations -  98793

Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.

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Influence of culture medium and protein supplementation on in vitro oocyte maturation and fertilization in the domestic cat.

TL;DR: These IVM/IVF oocytes were capable of culturing beyond 2-cells, with the highest proportion of 4- and 8- cell embryos forming in WAY and MEM media in the presence of BSA or in MEM medium containing PVA.
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Conservation Genetics of the Cheetah: Lessons Learned and New Opportunities

TL;DR: A synthesis of 3 decades of data, interpretation, and controversy, capped by whole genome sequence analysis of cheetahs, provides a compelling tale of conservation relevance and action to protect this species and other threatened wildlife.
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Evolution of heterochromatin-associated satellite DNA loci in felids and canids (Carnivora).

TL;DR: Cloned satellite DNAs that hybridize primarily to C-band-positive regions of felid and canid chromosomes were used to probe the organization of satellite families in the genomes of 16 species of felids and 15 species of canids, finding that satellite families within the canids appeared to be more uniform in regard to both amount/sequence and restriction patterns.
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Semen characteristics in free-living koalas (Phascolarctos cinereus)

TL;DR: These data confirm that free-living koalas normally produce spermatozoa with a high incidence of structural heterogeneity almost solely confined to the head region; and demonstrate the utility and safety of conventional gamete and endocrine studies, approaches which will be useful for determining the impact of genetic isolation and venereal disease on species fertility.
Journal Article

Characterization of MHC cDNA clones in the domestic cat. Diversity and evolution of class I genes.

TL;DR: Southern analysis of DNA from diverse species of Felidae revealed a similar numerosity and restriction pattern indicating conservation of the organization of class I genes during the Felidae radiation.