S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
Stephen J. O'Brien,John P. Moore +1 more
TL;DR: Genetic ablation of AIDS progression by chemokine receptor and ligand gene variants has catalyzed development of novel therapies targeting the virus-co-receptor interaction.
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Lateral epicondylitis : correlation of MR imaging, surgical, and histopathologic findings
Hollis G. Potter,Jo A. Hannafin,R M Morwessel,Edward F. DiCarlo,Stephen J. O'Brien,David W. Altchek +5 more
TL;DR: The use of MR imaging in patients with recalcitrant lateral epicondylitis assists in surgical planning because the definition of tendon degeneration and degree of tear, as depicted on MR images, correlate well with surgical and histologic findings.
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A role for molecular genetics in biological conservation
TL;DR: The consequences of genetic depletion revealed by applying molecular population genetic analysis to four endangered mammals are reviewed, including African cheetah, lion, Florida panther, and humpback whale.
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Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary
Johannes Krause,Tina Unger,Nocon Aline,Anna-Sapfo Malaspinas,Sergios-Orestis Kolokotronis,Sergios-Orestis Kolokotronis,Mathias Stiller,Leopoldo Héctor Soibelzon,Helen Spriggs,Paul H. Dear,Adrian W. Briggs,Sarah C Bray,Stephen J. O'Brien,Gernot Rabeder,Paul Matheus,Alan Cooper,Montgomery Slatkin,Svante Pääbo,Michael Hofreiter +18 more
TL;DR: This paper presented a fully resolved phylogeny for ursids based on ten complete mitochondrial genome sequences from all eight living and two recently extinct bear species, the European cave bear (Ursus spelaeus) and the American giant short-faced bear (Arctodus simus).
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Complete Nucleotide Sequences of the Domestic Cat (Felis catus) Mitochondrial Genome and a Transposed mtDNA Tandem Repeat (Numt) in the Nuclear Genome
TL;DR: Phylogenetic analysis of mitochondrial gene sequences confirms the recent transfer of the cytoplasmic mtDNA sequences to the domestic cat nucleus and recapitulates evolutionary relationships between mammal species.