S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
DNA Variation of the Mammalian Major Histocompatibility Complex Reflects Genomic Diversity and Population History
Naoya Yuhki,Stephen J. O'Brien +1 more
TL;DR: In this paper, a quantitative analysis of restriction fragment length polymorphism of MHC class I genes in several mammalian species (cat, rodents, humans) known to have very different levels of genetic diversity based on functional MHC assays and on allozyme surveys is presented.
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Capsular restraints to anterior-posterior motion of the abducted shoulder: a biomechanical study.
TL;DR: This study quantifies for the first time the normal amount of anterior-posterior translation in the intact cadaveric shoulder model and demonstrates the relative role of the anterior and posterior band of the inferior glenohumeral ligament complex in stabilizing the glenOHumeral joint at 90 degrees of abduction, where most clinical instability of the shoulder occurs.
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East African cheetahs: evidence for two population bottlenecks?
Stephen J. O'Brien,David E. Wildt,Mitchell Bush,Tim Caro,Clare D. Fitzgibbon,Issa Aggundey,Richard E. Leakey +6 more
TL;DR: It is proposed that at least two population bottlenecks followed by inbreeding produced the modern cheetah species.
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Immunologic and virologic response to highly active antiretroviral therapy in the Multicenter AIDS Cohort Study
Traci E. Yamashita,John P. Phair,Alvaro Muñoz,Joseph B. Margolick,Roger Detels,Stephen J. O'Brien,John W. Mellors,Steven M. Wolinsky,Lisa P. Jacobson +8 more
TL;DR: Immunologic and virologic response to HAART was stronger in individuals who had no prior experience with the antiretroviral therapy agents subsequently included in their initial HAART regimen.
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Chromosomal-level assembly of the Asian seabass genome using long sequence reads and multi-layered scaffolding
Shubha Vij,Heiner Kuhl,Inna S. Kuznetsova,Inna S. Kuznetsova,Aleksey Komissarov,Andrey A. Yurchenko,Peter van Heusden,Siddharth Singh,Natascha May Thevasagayam,Sai Rama Sridatta Prakki,Kathiresan Purushothaman,Jolly M. Saju,Junhui Jiang,Stanley Kimbung Mbandi,Mario Jonas,Amy Hin Yan Tong,Sarah Mwangi,Doreen Lau,Si Yan Ngoh,Woei Chang Liew,Xueyan Shen,Lawrence S. Hon,James P Drake,Matthew Boitano,Richard Hall,Chen-Shan Chin,Ramkumar Lachumanan,Jonas Korlach,Vladimir A. Trifonov,Marsel R. Kabilov,Alexey E. Tupikin,Darrell Green,Simon Moxon,Tyler Garvin,Fritz J. Sedlazeck,Fritz J. Sedlazeck,Gregory Vurture,Gopikrishna Gopalapillai,Vinaya Kumar Katneni,Tansyn Noble,Vinod Scaria,Sridhar Sivasubbu,Dean R. Jerry,Stephen J. O'Brien,Stephen J. O'Brien,Michael C. Schatz,Michael C. Schatz,Tamas Dalmay,Stephen Turner,Si Lok,Alan Christoffels,László Orbán,László Orbán,László Orbán +53 more
TL;DR: The quality of the Asian seabass genome assembly far exceeds that of any other fish species, and will serve as a new standard for fish genomics.