S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Diversity of MICA and Linkage Disequilibrium with HLA-B in Two North American Populations
Xiaojiang Gao,Richard M. Single,Peter Karacki,Darlene Marti,Stephen J. O'Brien,Mary Carrington +5 more
TL;DR: The lack of evidence for an active diversification of the MICA gene after racial separation indicates an evolutionary history distinct from that of the classical HLA genes.
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Reflex Sympathetic Dystrophy of the Knee Causes, Diagnosis, and Treatment
TL;DR: The need for establishing a pre cise diagnosis of reflex sympathetic dystrophy before contemplating any surgery of the knee, including arthroscopy, is emphasized.
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Clouded leopard phylogeny revisited: support for species recognition and population division between Borneo and Sumatra.
Andreas Wilting,Valerie A. Buckley-Beason,Heike Feldhaar,Juergen Gadau,Stephen J. O'Brien,K. Eduard Linsenmair +5 more
TL;DR: Strong support is found for the distinction between N. nebulosa and N. diardi based on three fragments of mtDNA and 18 microsatellites, equivalent to the genetic divergence among recognized species in the genus Panthera.
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Long-term nonprogressive infection with human immunodeficiency virus type 1 in a hemophilia cohort.
Thomas C. Greenough,Doreen B. Brettler,Frank Kirchhoff,Louis Alexander,Ronald C. Desrosiers,Stephen J. O'Brien,Mohan Somasundaran,Katherine Luzuriaga,John L. Sullivan +8 more
TL;DR: LTNPs in this cohort have maintained remarkably low virus burdens and vigorous HIV-1-specific cell-mediated immunity over a 15-year period, and the presence of expanded, activated CD8 T cells with cytotoxic effector function in the peripheral blood suggests ongoing viral replication.
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Endogenous Retrovirus Insertion in the KIT Oncogene Determines White and White spotting in Domestic Cats
Victor A. David,Marilyn Menotti-Raymond,Andrea Coots Wallace,Melody E. Roelke,James Kehler,Robert Leighty,Eduardo Eizirik,Steven S. Hannah,George E. Nelson,Alejandro A. Schäffer,Catherine J. Connelly,Stephen J. O'Brien,David K. Ryugo +12 more
TL;DR: A large-population genetic survey of cats, representing 30 cat breeds, supports the findings and demonstrates statistical significance of the FERV1 LTR and full-length element with Dominant White/blue iris and white spotting.