S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Chromosomer: a reference-based genome arrangement tool for producing draft chromosome sequences.
Gaik Tamazian,Pavel Dobrynin,Ksenia Krasheninnikova,Aleksey Komissarov,Klaus-Peter Koepfli,Klaus-Peter Koepfli,Stephen J. O'Brien,Stephen J. O'Brien +7 more
TL;DR: Chromosomer is a reference-based genome arrangement tool, which rapidly builds chromosomes from genome contigs or scaffolds using their alignments to a reference genome of a closely related species, and is a useful tool for genomic analysis of species without chromosome maps.
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Nuclear gene sequences confirm an ancient link between New Zealand’s short-tailed bat and South American noctilionoid bats
TL;DR: Maximum likelihood, minimum evolution, maximum parsimony, and Bayesian posterior probabilities all provide robust support for the association of Mystacina with the South American noctilionoids.
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Arthroscopic Assessment of the Medial Collateral Ligament Complex of the Elbow
TL;DR: The ability to reliably see the anterior bundle and the hu meral or ulnar insertion sites of this ligament may limit the value of the arthroscope when assessing medial collateral ligament injuries.
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Biological and Pathological Consequences of Feline Infectious Peritonitis Virus Infection in the Cheetah
TL;DR: Observations that the cheetah was genetically unusual insofar as large amounts of enzyme-encoding loci were monomorphic, and that unrelated cheetahs were capable of accepting allogenic skin grafts provided the basis for a hypothesis that theCheetah, through intensive inbreeding, had become more susceptible to viral infections as a result of genetic homogeneity.
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Defining and Mapping Mammalian Coat Pattern Genes: Multiple Genomic Regions Implicated in Domestic Cat Stripes and Spots
Eduardo Eizirik,Eduardo Eizirik,Victor A. David,Valerie A. Buckley-Beason,Melody E. Roelke,Alejandro A. Schäffer,Steven S. Hannah,Kristina Narfström,Stephen J. O'Brien,Marilyn Menotti-Raymond +9 more
TL;DR: It is hypothesized that mammalian patterned coats are formed by two distinct processes: a spatially oriented developmental mechanism that lays down a species-specific pattern of skin cell differentiation and a pigmentation-oriented mechanism that uses information from the preestablished pattern to regulate the synthesis of melanin profiles.