S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
Sudha K. Iyengar,John R. Sedor,Barry I. Freedman,W. H. Linda Kao,Matthias Kretzler,Benjamin J. Keller,Hanna E. Abboud,Sharon G. Adler,Lyle G. Best,Donald W. Bowden,Allison Burlock,Yii-Der Ida Chen,Shelley A. Cole,Mary E. Comeau,Jeffrey M. Curtis,Jasmin Divers,Christiane Drechsler,Ravi Duggirala,Robert C. Elston,Xiuqing Guo,Huateng Huang,Michael M. Hoffmann,Barbara V. Howard,Eli Ipp,Paul L. Kimmel,Michael J. Klag,William C. Knowler,Orly F. Kohn,Tennille S. Leak,David J. Leehey,Man Li,Alka Malhotra,Winfried März,Viji Nair,Robert G. Nelson,Susanne B. Nicholas,Stephen J. O'Brien,Madeleine V. Pahl,Rulan S. Parekh,Marcus G. Pezzolesi,Rebekah S. Rasooly,Charles N. Rotimi,Jerome I. Rotter,Jeffrey R. Schelling,Michael F. Seldin,Vallabh O. Shah,Adam M. Smiles,Michael W. Smith,Kent D. Taylor,Farook Thameem,Farook Thameem,Denyse Thornley-Brown,Barbara Truitt,Christoph Wanner,E. Jennifer Weil,Cheryl A. Winkler,Philip G. Zager,Robert P. Igo,Robert L. Hanson,Carl D. Langefeld +59 more
TL;DR: A novel DKD susceptibility locus with consistent directions of effect across diverse ancestral groups is identified with directionally consistent results across ethnic groups and provides insight into the genetic architecture of DKD.
Journal ArticleDOI
Comparative Genome Organization of Vertebrates
Leif Andersson,Alan Archibald,M. Ashburner,S. Audun,William Barendse,J. Bitgood,Cynthia D.K. Bottema,T. E. Broad,Stephen D.M. Brown,David W. Burt,Carole Charlier,Neal G. Copeland,Scott K. Davis,Muriel T. Davisson,J. Edwards,André Eggen,Greg Elgar,J. T. Eppig,I.R. Franklin,Peter M. Grewe,Theodore Gill,Jennifer A. Marshall Graves,R. J. Hawken,Jay Hetzel,A. Hilyard,Howard J. Jacob,L. Jaswinska,Nancy A. Jenkins,H. Kunz,Göran Levan,O. Lie,Leslie A. Lyons,P. Maccarone,Cathryn S. Mellersh,Grant W. Montgomery,Stephen S. Moore,Chris Moran,D. Morizot,M. Neff,Frank W. Nicholas,Stephen J. O'Brien,Yvonne M. Parsons,Josephine Peters,John H. Postlethwait,Marilyn Menotti Raymond,Max F. Rothschild,Lawrence B. Schook,Y. Sugimoto,Claude Szpirer,M. Tate,Jeremy F. Taylor,John L. VandeBerg,Matthew Wakefield,Johannes Wienberg,James E. Womack +54 more
TL;DR: In a recent paper as mentioned in this paper, the authors present an overview of the state-of-the-art work in animal genetics, focusing on the use of protein-protein interactions.
Journal ArticleDOI
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls
Paul J. McLaren,Paul J. McLaren,Paul J. McLaren,Cédric Coulonges,Stephan Ripke,Stephan Ripke,Leonard H. van den Berg,Susan Buchbinder,Mary Carrington,Mary Carrington,Andrea Cossarizza,Judith Dalmau,Steven G. Deeks,Olivier Delaneau,Andrea De Luca,James J. Goedert,David W. Haas,Joshua T. Herbeck,Sekar Kathiresan,Sekar Kathiresan,Gregory D. Kirk,Olivier Lambotte,Olivier Lambotte,Ma Luo,Ma Luo,Simon Mallal,Daniëlle van Manen,Daniëlle van Manen,Javier Martinez-Picado,Laurence Meyer,José M. Miró,James I. Mullins,Niels Obel,Stephen J. O'Brien,Florencia Pereyra,Florencia Pereyra,Francis A. Plummer,Francis A. Plummer,Guido Poli,Ying Qi,Pierre Rucart,M. S. Sandhu,M. S. Sandhu,Patrick R. Shea,Hanneke Schuitemaker,Hanneke Schuitemaker,Ioannis Theodorou,Fredrik O. Vannberg,Jan H. Veldink,Bruce D. Walker,Bruce D. Walker,Amy C. Weintrob,Cheryl A. Winkler,Steven M. Wolinsky,Amalio Telenti,David Goldstein,Paul I.W. de Bakker,Paul I.W. de Bakker,Paul I.W. de Bakker,Jean-François Zagury,Jacques Fellay,Jacques Fellay +61 more
TL;DR: Analysis of genome-wide single nucleotide polymorphism data collected by 25 cohorts, studies, or institutions on HIV-1 infected individuals and compared them to carefully matched population-level data sets suggest that genetic influences on HIV acquisition are either rare or have smaller effects than can be detected by this sample size.
Journal ArticleDOI
Molecular Analysis of Integrated Human Papillomavirus 16 Sequences in the Cervical Cancer Cell Line SiHa
TL;DR: The observation of viral-cell transcripts and chromosomal deletions associated with HPV integration may indicate that such events are part of a multistep mechanism leading to the development of cervical cancer.
Journal ArticleDOI
Comprehensive Analysis of Class I and Class II HLA Antigens and Chronic Hepatitis B Virus Infection
Chloe L. Thio,David L. Thomas,Peter Karacki,Xiaojiang Gao,Darlene Marti,Richard A. Kaslow,James J. Goedert,Margaret W. Hilgartner,Steffanie A. Strathdee,Priya Duggal,Stephen J. O'Brien,Jacquie Astemborski,Mary Carrington +12 more
TL;DR: The associations with class I alleles are consistent with a previously implicated role for CD8-mediated cytolytic-T-cell response in determining the outcome of an acute HBV infection.