Chonbuk National University

About: Chonbuk National University is a education organization based out in Jeonju, South Korea. It is known for research contribution in the topics: Apoptosis & Graphene. The organization has 14820 authors who have published 28884 publications receiving 554131 citations.

Mechanical behavior of electrospun fiber mats of poly(vinyl chloride)/polyurethane polyblends

Abstract: Various polyblends of poly(vinyl chloride) and polyurethane (PU) dissolved in a mixture of tetrahydrofuran and N,N-dimethylformamide were produced by electrospinning, in different ratios, with several electrospinning conditions, and the relationship between morphology and mechanical behavior of the resulting fiber mats was examined in detail. The surface tension, viscosity, and electrical conductivity of polymer solutions affecting electrospinning were measured, and scanning electron microscopy (SEM) along with a universal testing machine were used to examine the family of polyblends under investigation. The SEM images demonstrated that point-bonded structures in the fiber mats rose with increasing PU composition, and the mechanical properties of the fiber mats, as determined in a static tensile test, can be considered to have a strong effect by the point-bonded structure. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 41: 1256–1262, 2003

Technologies for circulating tumor cell separation from whole blood

Abstract: The importance of early cancer diagnosis and improved cancer therapy has been clear for years and has initiated worldwide research towards new possibilities in the care strategy of patients with cancer using technological innovations. One of the key research fields involves the separation and detection of circulating tumor cells (CTC) because of their suggested important role in early cancer diagnosis and prognosis, namely, providing easy access by a liquid biopsy from blood to identify metastatic cells before clinically detectable metastasis occurs and to study the molecular and genetic profile of these metastatic cells. Provided the opportunity to further progress the development of technology for treating cancer, several CTC technologies have been proposed in recent years by various research groups and companies. Despite their potential role in cancer healthcare, CTC methods are currently mainly used for research purposes, and only a few methods have been accepted for clinical application because of the difficulties caused by CTC heterogeneity, CTC separation from the blood, and a lack of thorough clinical validation. Therefore, the standardization and clinical application of various developed CTC technologies remain important subsequent necessary steps. Because of their suggested future clinical benefits, we focus on describing technologies using whole blood samples without any pretreatment and discuss their advantages, use, and significance. Technologies using whole blood samples utilize size-based, immunoaffinity-based, and density-based methods or combinations of these methods as well as positive and negative enrichment during separation. Although current CTC technologies have not been truly implemented yet, they possess high potential as future clinical diagnostic techniques for the individualized therapy of patients with cancer. Thus, a detailed discussion of the clinical suitability of these new advanced technologies could help prepare clinicians for the future and can be a foundation for technologies that would be used to eliminate CTCs in vivo.

Ultrasmooth, extremely deformable and shape recoverable Ag nanowire embedded transparent electrode

Abstract: Transparent electrodes have been widely used in electronic devices such as solar cells, displays, and touch screens Highly flexible transparent electrodes are especially desired for the development of next generation flexible electronic devices Although indium tin oxide (ITO) is the most commonly used material for the fabrication of transparent electrodes, its brittleness and growing cost limit its utility for flexible electronic devices Therefore, the need for new transparent conductive materials with superior mechanical properties is clear and urgent Ag nanowire (AgNW) has been attracting increasing attention because of its effective combination of electrical and optical properties However, it still suffers from several drawbacks, including large surface roughness, instability against oxidation and moisture, and poor adhesion to substrates These issues need to be addressed before wide spread use of metallic NW as transparent electrodes can be realized In this study, we demonstrated the fabrication of a flexible transparent electrode with superior mechanical, electrical and optical properties by embedding a AgNW film into a transparent polymer matrix This technique can produce electrodes with an ultrasmooth and extremely deformable transparent electrode that have sheet resistance and transmittance comparable to those of an ITO electrode