Institution
Nanjing University
Education•Nanjing, China•
About: Nanjing University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: Catalysis & Adsorption. The organization has 85961 authors who have published 105504 publications receiving 2289036 citations. The organization is also known as: NJU & Nanking University.
Topics: Catalysis, Adsorption, Population, Computer science, Thin film
Papers published on a yearly basis
Papers
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TL;DR: This work shows that x-ray flares discovered in two short gamma-ray bursts last much longer than the previously proposed postmerger energy-release time scales and can be produced by differentially rotating, millisecond pulsars after the mergers of binary neutron stars.
Abstract: Recent observations support the suggestion that short-duration gamma-ray bursts are produced by compact star mergers. The x-ray flares discovered in two short gamma-ray bursts last much longer than the previously proposed postmerger energy-release time scales. Here, we show that they can be produced by differentially rotating, millisecond pulsars after the mergers of binary neutron stars. The differential rotation leads to windup of interior poloidal magnetic fields and the resulting toroidal fields are strong enough to float up and break through the stellar surface. Magnetic reconnection-driven explosive events then occur, leading to multiple x-ray flares minutes after the original gamma-ray burst.
410 citations
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TL;DR: Nine single-base resolution DNA methylomes are generated, including zebrafish gametes and early embryos, and it is shown that inheritance of the sperm methylome facilitates the epigenetic regulation of embryogenesis.
410 citations
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TL;DR: This paper proposes the MimlBoost and MimlSvm algorithms based on a simple degeneration strategy, and experiments show that solving problems involving complicated objects with multiple semantic meanings in the MIML framework can lead to good performance.
409 citations
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TL;DR: It is expected this Au NPs-based Hg(2+) sensor will be a promising candidate for field detection of environmentally toxic mercury and exhibits excellent selectivity over a spectrum of interference metal ions.
Abstract: We report a highly sensitive electrochemical sensor for the detection of Hg2+ ions in aqueous solution by using a thymine (T)-rich, mercury-specific oligonucleotide (MSO) probe and gold nanoparticles (Au NPs)-based signal amplification. The MSO probe contains seven thymine bases at both ends and a “mute” spacer in the middle, which, in the presence of Hg2+, forms a hairpin structure via the Hg2+-mediated coordination of T−Hg2+−T base pairs. The thiolated MSO probe is immobilized on Au electrodes to capture free Hg2+ in aqueous media, and the MSO-bound Hg2+ can be electrochemically reduced to Hg+, which provides a readout signal for quantitative detection of Hg2+. This direct immobilization strategy leads to a detection limit of 1 μM. In order to improve the sensitivity, MSO probe-modified Au NPs are employed to amplify the electrochemical signals. Au NPs are comodified with the MSO probe and a linking probe that is complementary to a capture DNA probe immobilized on gold electrodes. We demonstrated that t...
409 citations
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TL;DR: This protocol describes how to carry out the sucrose preference test (SPT) in a standardized way to reduce data variability and provides a detailed protocol to ensure greater consistency when carrying out SPT.
Abstract: Anhedonia is the inability to experience pleasure from rewarding or enjoyable activities and is a core symptom of depression in humans. Here, we describe a protocol for the measurement of anhedonia in mice, in which anhedonia is measured by a sucrose preference test (SPT) based on a two-bottle choice paradigm. A reduction in the sucrose preference ratio in experimental relative to control mice is indicative of anhedonia. To date, inconsistent and variable results have been reported following the use of the SPT by different groups, probably due to the use of different protocols and equipment. In this protocol, we describe how to set up a clearly defined apparatus for SPT and provide a detailed protocol to ensure greater consistency when carrying out SPT. This optimized protocol is highly sensitive, reliable, and adaptable for evaluation of chronic stress-related anhedonia, as well as morphine-induced dependence. The whole SPT, including adaptation, baseline measurement, and testing, takes 8 d.
409 citations
Authors
Showing all 86514 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
H. S. Chen | 179 | 2401 | 178529 |
Zhenan Bao | 169 | 865 | 106571 |
Gang Chen | 167 | 3372 | 149819 |
Peter G. Schultz | 156 | 893 | 89716 |
Xiang Zhang | 154 | 1733 | 117576 |
Rui Zhang | 151 | 2625 | 107917 |
Yi Yang | 143 | 2456 | 92268 |
Markku Kulmala | 142 | 1487 | 85179 |
Jian Yang | 142 | 1818 | 111166 |
Wei Huang | 139 | 2417 | 93522 |
Bin Liu | 138 | 2181 | 87085 |
Jun Lu | 135 | 1526 | 99767 |
Hui Li | 135 | 2982 | 105903 |
Lei Zhang | 135 | 2240 | 99365 |