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Institution

Oregon State University

EducationCorvallis, Oregon, United States
About: Oregon State University is a education organization based out in Corvallis, Oregon, United States. It is known for research contribution in the topics: Population & Gene. The organization has 28192 authors who have published 64044 publications receiving 2634108 citations. The organization is also known as: Oregon Agricultural College & OSU.


Papers
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Journal ArticleDOI
15 Sep 2005-Nature
TL;DR: The history of microbial evolution in the oceans is probably as old as the history of life itself, but whether microbial plankton populations harbour organisms that are models of adaptive sophistication remains to be seen.
Abstract: The history of microbial evolution in the oceans is probably as old as the history of life itself. In contrast to terrestrial ecosystems, microorganisms are the main form of biomass in the oceans, and form some of the largest populations on the planet. Theory predicts that selection should act more efficiently in large populations. But whether microbial plankton populations harbour organisms that are models of adaptive sophistication remains to be seen. Genome sequence data are piling up, but most of the key microbial plankton clades have no cultivated representatives, and information about their ecological activities is sparse.

546 citations

Journal ArticleDOI
TL;DR: The recent identification of one class of fluorinated surfactants in groundwater impacted by fire-fighting activity has created an awareness of the potential environmental issues resulting from the firefighting activity as mentioned in this paper.
Abstract: The recent identification of one class of fluorinated surfactants in groundwater impacted by fire-fighting activity has created an awareness of the potential environmental issues resulting from the...

545 citations

Journal ArticleDOI
01 Jan 1988
TL;DR: Conclusions on Circular Dichroism Spectra for Pure Secondary Structures and Changes in Secondary Structure with Solvent Variation are published.
Abstract: CIRCULAR DICHROISM SPECTROSCOPY .........•.....••......• • 147 Technique .. ...... . . . . .. . . . . . . . . . . . . . . . . . . ...... .... ........ . . . .... 147 Spectrometers.... . . . . . . .... . . . . . . ........ . ...... . . . . . . . . . . . . .... . . . .... . . . ...... . . . . ...... . . . ..... 148 Concentration and Pathlength.. . . . . . . ...... ..... . . . ...... .... ..... . . . .. . . . . ....... .... . . . ... . . . . 149 Noise .. .... . . . . ... . . . . . ....... . . . . . . . . . . . . ... . . ........ ........ ........ . ...... 150 METHODS OF ANALySIS 151 Information Content and Constraints .... . . . . . . . . . . .. . . . .... . ... . . . . ...... ... . ........ . . . . . ... . . 151 Circular Dichroism Spectra for Pure Secondary Structures ...... . . . . . .. . . . . . ... . . . . . . . . . . .. . . . . . 152 Reference Circular Dichroism From Proteins of Known Secondary Structure . . . .... . . . . 154 APPLICATIONS . ......... ..... . . . . . .... . . . . .. . . . ... 159 Analysisfor Secondary Structure......... . . . ..... . . . .. . . . . . ....... .... . . . ....... 159 Proteins With Denatured Circular Dichroism . . . . ..... .. ....... . . . . . . . . .... . 160 Changes in Secondary Structure on Ligand Binding ..... . . . . . . . . . . . . . ... . . . ..... . . ......... 161 Changes in Secondary Structure With Solvent Variation ......... ..... . . ..... . . ..... . ..... . . . ..... 162 Changes in Secondary Structure on Protein Denaturation.... ........ . . . ...... . . .. . . . . . 163 CONCLUSIONS.... ...... ....... ........ 164

545 citations

Journal ArticleDOI
TL;DR: A precipitous drop in costs and increase in sequencing efficiency is anticipated, with concomitant development of improved annotation technology, and it is proposed to create a collection of tissue and DNA specimens for 10,000 vertebrate species specifically designated for whole-genome sequencing in the very near future.
Abstract: American Genetic Association, Gordon and Betty Moore Foundation, NHGRI Intramural Sequencing Center, and UCSC Alumni Association to cost of the Genome 10K workshop; Howard Hughes Medical Institute to D. H.; Gordon and Betty Moore Foundation to S. C. S.; A

545 citations

Journal ArticleDOI
TL;DR: The r package vcfr provides essential, novel tools currently not available in r to facilitate VCF data exploration, including intuitive methods for data quality control and easy export to other r packages for further analysis.
Abstract: Software to call single-nucleotide polymorphisms or related genetic variants has converged on the variant call format (VCF) as the output format of choice. This has created a need for tools to work with VCF files. While an increasing number of software exists to read VCF data, many only extract the genotypes without including the data associated with each genotype that describes its quality. We created the r package vcfr to address this issue. We developed a VCF file exploration tool implemented in the r language because r provides an interactive experience and an environment that is commonly used for genetic data analysis. Functions to read and write VCF files into r as well as functions to extract portions of the data and to plot summary statistics of the data are implemented. vcfr further provides the ability to visualize how various parameterizations of the data affect the results. Additional tools are included to integrate sequence (fasta) and annotation data (GFF) for visualization of genomic regions such as chromosomes. Conversion functions translate data from the vcfr data structure to formats used by other r genetics packages. Computationally intensive functions are implemented in C++ to improve performance. Use of these tools is intended to facilitate VCF data exploration, including intuitive methods for data quality control and easy export to other r packages for further analysis. vcfr thus provides essential, novel tools currently not available in r.

544 citations


Authors

Showing all 28447 results

NameH-indexPapersCitations
Robert Stone1601756167901
Menachem Elimelech15754795285
Thomas J. Smith1401775113919
Harold A. Mooney135450100404
Jerry M. Melillo13438368894
John F. Thompson132142095894
Thomas N. Williams132114595109
Peter M. Vitousek12735296184
Steven W. Running12635576265
Vincenzo Di Marzo12665960240
J. D. Hansen12297576198
Peter Molnar11844653480
Michael R. Hoffmann10950063474
David Pollard10843839550
David J. Hill107136457746
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023105
2022377
20213,156
20203,109
20193,017
20182,987