Showing papers by "Russian Academy of Sciences published in 2002"

The entropy formula for the Ricci flow and its geometric applications

Abstract: We present a monotonic expression for the Ricci flow, valid in all dimensions and without curvature assumptions. It is interpreted as an entropy for a certain canonical ensemble. Several geometric applications are given. In particular, (1) Ricci flow, considered on the space of riemannian metrics modulo diffeomorphism and scaling, has no nontrivial periodic orbits (that is, other than fixed points); (2) In a region, where singularity is forming in finite time, the injectivity radius is controlled by the curvature; (3) Ricci flow can not quickly turn an almost euclidean region into a very curved one, no matter what happens far away. We also verify several assertions related to Richard Hamilton's program for the proof of Thurston geometrization conjecture for closed three-manifolds, and give a sketch of an eclectic proof of this conjecture, making use of earlier results on collapsing with local lower curvature bound.

Genetic Structure of Human Populations

Abstract: We studied human population structure using genotypes at 377 autosomal microsatellite loci in 1056 individuals from 52 populations. Within-population differences among individuals account for 93 to 95% of genetic variation; differences among major groups constitute only 3 to 5%. Nevertheless, without using prior information about the origins of individuals, we identified six main genetic clusters, five of which correspond to major geographic regions, and subclusters that often correspond to individual populations. General agreement of genetic and predefined populations suggests that self-reported ancestry can facilitate assessments of epidemiological risks but does not obviate the need to use genetic information in genetic association studies.

Natively unfolded proteins: a point where biology waits for physics.

Abstract: The experimental material accumulated in the literature on the conformational behavior of intrinsically unstructured (natively unfolded) proteins was analyzed. Results of this analysis showed that these proteins do not possess uniform structural properties, as expected for members of a single thermodynamic entity. Rather, these proteins may be divided into two structurally different groups: intrinsic coils, and premolten globules. Proteins from the first group have hydrodynamic dimensions typical of random coils in poor solvent and do not possess any (or almost any) ordered secondary structure. Proteins from the second group are essentially more compact, exhibiting some amount of residual secondary structure, although they are still less dense than native or molten globule proteins. An important feature of the intrinsically unstructured proteins is that they undergo disorder–order transition during or prior to their biological function. In this respect, the Protein Quartet model, with function arising from four specific conformations (ordered forms, molten globules, premolten globules, and random coils) and transitions between any two of the states, is discussed.

The genome sequence of Schizosaccharomyces pombe

Abstract: We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which there are 4,730. Fifty genes have significant similarity with human disease genes; half of these are cancer related. We identify highly conserved genes important for eukaryotic cell organization including those required for the cytoskeleton, compartmentation, cell-cycle control, proteolysis, protein phosphorylation and RNA splicing. These genes may have originated with the appearance of eukaryotic life. Few similarly conserved genes that are important for multicellular organization were identified, suggesting that the transition from prokaryotes to eukaryotes required more new genes than did the transition from unicellular to multicellular organization.

Observation of coupled magnetic and electric domains

Abstract: Ferroelectromagnets are an interesting group of compounds that complement purely (anti-)ferroelectric or (anti-)ferromagnetic materials--they display simultaneous electric and magnetic order. With this coexistence they supplement materials in which magnetization can be induced by an electric field and electrical polarization by a magnetic field, a property which is termed the magnetoelectric effect. Aside from its fundamental importance, the mutual control of electric and magnetic properties is of significant interest for applications in magnetic storage media and 'spintronics'. The coupled electric and magnetic ordering in ferroelectromagnets is accompanied by the formation of domains and domain walls. However, such a cross-correlation between magnetic and electric domains has so far not been observed. Here we report spatial maps of coupled antiferromagnetic and ferroelectric domains in YMnO3, obtained by imaging with optical second harmonic generation. The coupling originates from an interaction between magnetic and electric domain walls, which leads to a configuration that is dominated by the ferroelectromagnetic product of the order parameters.

Absorption and Emission of Hexagonal InN. Evidence of Narrow Fundamental Band Gap.

Abstract: (a) Ioffe Physico-Technical Institute, Russian Academy of Science, Polytekhnicheskaya 26, 194021 St. Petersburg, Russia (b) Institut für Festkörpertheorie and Theoretische Optik, Friedrich-Schiller-Universität Jena, Max-Wien-Platz 1, D-07743 Jena, Germany (c) Department of Electronics and Information Science, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan (d) Institute of Solid State and Semiconductor Physics, Belarus Academy of Sciences, Brovki 17, 220072 Minsk, Belarus (e) LfI, University of Hannover, Schneiderberg 32, D-30167 Hannover, Germany

What does it mean to be natively unfolded

Abstract: Natively unfolded or intrinsically unstructured proteins constitute a unique group of the protein kingdom. The evolutionary persistence of such proteins represents strong evidence in the favor of their importance and raises intriguing questions about the role of protein disorders in biological processes. Additionally, natively unfolded proteins, with their lack of ordered structure, represent attractive targets for the biophysical studies of the unfolded polypeptide chain under physiological conditions in vitro. The goal of this study was to summarize the structural information on natively unfolded proteins in order to evaluate their major conformational characteristics. It appeared that natively unfolded proteins are characterized by low overall hydrophobicity and large net charge. They possess hydrodynamic properties typical of random coils in poor solvent, or premolten globule conformation. These proteins show a low level of ordered secondary structure and no tightly packed core. They are very flexible, but may adopt relatively rigid conformations in the presence of natural ligands. Finally, in comparison with the globular proteins, natively unfolded polypeptides possess 'turn out' responses to changes in the environment, as their structural complexities increase at high temperature or at extreme pH.

Origin of apparent colossal dielectric constants

Abstract: Experimental evidence is provided that colossal dielectric constants ${\ensuremath{\varepsilon}}^{\ensuremath{'}}g~1000,$ sometimes reported to exist in a broad temperature range, can often be explained by Maxwell-Wagner-type contributions of depletion layers at the interface between sample and contacts or at grain boundaries. We demonstrate this on a variety of different materials. We speculate that the largest intrinsic dielectric constant observed so far in nonferroelectric materials is of order ${10}^{2}.$

Electron spin relaxation by nuclei in semiconductor quantum dots

Abstract: We have studied theoretically electron spin relaxation in semiconductor quantum dots via interaction with nuclear spins. The relaxation is shown to be determined by three processes: (i) the precession of the electron spin in the hyperfine field of the frozen fluctuation of the nuclear spins; (ii) the precession of the nuclear spins in the hyperfine field of the electron; and (iii) the precession of the nuclear spin in the dipole field of its nuclear neighbors. In external magnetic fields the relaxation of electron spins directed along the magnetic field is suppressed. Electron spins directed transverse to the magnetic field relax completely in a time on the order of the precession period of its spin in the field of the frozen fluctuation of the nuclear spins. Comparison with experiment shows that the hyperfine interaction with nuclei may be the dominant mechanism of electron spin relaxation in quantum dots.

Microbial reefs in the Black Sea fueled by anaerobic oxidation of methane

Abstract: Massive microbial mats covering up to 4-meter-high carbonate buildups prosper at methane seeps in anoxic waters of the northwestern Black Sea shelf. Strong 13C depletions indicate an incorporation of methane carbon into carbonates, bulk biomass, and specific lipids. The mats mainly consist of densely aggregated archaea (phylogenetic ANME-1 cluster) and sulfate-reducing bacteria (Desulfosarcina/Desulfococcus group). If incubated in vitro, these mats perform anaerobic oxidation of methane coupled to sulfate reduction. Obviously, anaerobic microbial consortia can generate both carbonate precipitation and substantial biomass accumulation, which has implications for our understanding of carbon cycling during earlier periods of Earth's history.

Exhumation of high-pressure metamorphic rocks in a subduction channel: A numerical simulation

Abstract: [1] High-pressure metamorphic rocks provide evidence that in subduction zones material can return from depths of more than 100 km to the surface. The pressure-temperature paths recorded by these rocks are variable, mostly revealing cooling during decompression, while the time constraints are generally narrow and indicate that the exhumation rates can be on the order of plate velocities. As such, subduction cannot be considered as a single pass process; instead, return flow of a considerable portion of crustal and upper mantle material must be accounted for. Our numerical simulations provide insight into the self-organizing large-scale flow patterns and temperature field of subduction zones, primarily controlled by rheology, phase transformations, fluid budget, and heat transfer, which are all interrelated. They show the development of a subduction channel with forced return flow of low-viscosity material and progressive widening by hydration of the mantle wedge. The large-scale structures and the array of pressure-temperature paths obtained by these simulations favorably compare to the record of natural rocks and the structure of high-pressure metamorphic areas.

Seismic Images of Crust and Upper Mantle Beneath Tibet: Evidence for Eurasian Plate Subduction

Abstract: Seismic data from central Tibet have been combined to image the subsurface structure and understand the evolution of the collision of India and Eurasia. The 410- and 660-kilometer mantle discontinuities are sharply defined, implying a lack of a subducting slab beneath the plateau. The discontinuities appear slightly deeper beneath northern Tibet, implying that the average temperature of the mantle above the transition zone is about 300°C hotter in the north than in the south. There is a prominent south-dipping converter in the uppermost mantle beneath northern Tibet that might represent the top of the Eurasian mantle lithosphere underthrusting the northern margin of the plateau.

The marine ecosystem of Kongsfjorden, Svalbard

Abstract: Kongsfjorden is a glacial fjord in the Arctic (Svalbard) that is influenced by both Atlantic and Arctic water masses and harbours a mixture of boreal and Arctic flora and fauna. Inputs from large tidal glaciers create steep environmental gradients in sedimentation and salinity along the length of this fjord. The glacial inputs cause reduced biomass and diversity in the benthic community in the inner fjord. Zooplankton suffers direct mortality from the glacial outflow and primary production is reduced because of limited light levels in the turbid, mixed inner waters. The magnitude of the glacial effects diminishes towards the outer fjord. Kongsfjorden is an important feeding ground for marine mammals and seabirds. Even though the fjord contains some boreal fauna, the prey consumed by upper trophic levels is mainly Arctic organisms. Marine mammals constitute the largest top-predator biomass, but seabirds have the largest energy intake and also export nutrients and energy out of the marine environment. Kongsfjorden has received a lot of research attention in the recent past. The current interest in the fjord is primarily based on the fact that Kongsfjorden is particularly suitable as a site for exploring the impacts of possible climate changes, with Atlantic water influx and melting of tidal glaciers both being linked to climate variability. The pelagic ecosystem is likely to be most sensitive to the Atlantic versus Arctic influence, whereas the benthic ecosystem is more affected by long-term changes in hydrography as well as changes in glacial runoff and sedimentation. Kongsfjorden will be an important Arctic monitoring site over the coming decades and a review of the current knowledge, and a gap analysis, are therefore warranted. Important knowledge gaps include a lack of quantitative data on production, abundance of key prey species, and the role of advection on the biological communities in the fjord.

Earth system models of intermediate complexity: closing the gap in the spectrum of climate system models

Abstract: We propose a new perspective on the hierarchy of climate models which goes beyond the ''classical'' climate modeling pyramid that is restricted mainly to atmospheric processes, Most notably, we introduce a new indicator, called ''integration'', which characterizes the number of interacting components of the climate system being explicitly described in a model. The location of several model types, from conceptual to comprehensive, is presented in a new spectrum of climate system models. In particular. the location of the Earth system Models of Intermediate Complexity (EMICs) in this spectrum is discussed in some detail and examples are given, which indicate that there is currently a broad range of EMICs in use. In some EMICs, the number of processes and/or the detail of description is reduced for the sake of simulating the feedbacks between as many components of the climate system as feasible. Others, with a lesser degree of interaction, or ''integration'', are used for long-term ensemble simulations to study specific aspects of climate variability. EMICs appear to be closer to comprehensive coupled models of atmospheric and oceanic circulation (CGCMs) than to ''conceptual'' or ''box'' models. We advocate that EMICs be considered as complementary to CGCMs and conceptual models, because we believe that there is an advantage of having a spectrum of climate system models which are designed to tackle specific aspects of climate and which together provide the proper tool for climate system modeling.

Truncated product method for combining P‐values

Abstract: We present a new procedure for combining P-values from a set of L hypothesis tests. Our procedure is to take the product of only those P-values less than some specified cut-off value and to evaluate the probability of such a product, or a smaller value, under the overall hypothesis that all L hypotheses are true. We give an explicit formulation for this P-value, and find by simulation that it can provide high power for detecting departures from the overall hypothesis. We extend the procedure to situations when tests are not independent. We present both real and simulated examples where the method is especially useful. These include exploratory analyses when L is large, such as genome-wide scans for marker-trait associations and meta-analytic applications that combine information from published studies, with potential for dealing with the "publication bias" phenomenon. Once the overall hypothesis is rejected, an adjustment procedure with strong family-wise error protection is available for smaller subsets of hypotheses, down to the individual tests.

Feasibility of using laser ion accelerators in proton therapy

Abstract: The feasibility of using laser plasma as a source of high-energy ions for the purposes of proton therapy is discussed The proposal is based on the efficient ion acceleration observed in recent laboratory and numerical experiments on the interaction of high-power laser radiation with gaseous and solid targets The specific dependence of proton energy losses in biological tissues (the Bragg peak) promotes the solution of one of the main problems of radiation therapy, namely, the irradiation of a malignant tumor with a sufficiently strong and homogeneous dose, ensuring that the irradiation of the surrounding healthy tissues and organs is minimal In the scheme proposed, a beam of fast ions accelerated by a laser pulse can be integrated in the installations intended for proton therapy

Mn 3s exchange splitting in mixed-valence manganites.

Abstract: We present Mn $3s$ x-ray photoelectron spectra of manganese oxides with the Mn formal valency from $2+$ to $4+.$ We found that the ${\mathrm{Sr}}^{2+}$ doping or cation deficiency in manganites do not change the Mn $3s$ splitting in manganites with the Mn formal valency from $3.0+$ to $3.3+.$ We suggest that doping holes are localized in O $2p$ states.

Macroscopically ordered state in an exciton system

Abstract: There is a rich variety of quantum liquids—such as superconductors, liquid helium and atom Bose–Einstein condensates—that exhibit macroscopic coherence in the form of ordered arrays of vortices1,2,3,4. Experimental observation of a macroscopically ordered electronic state in semiconductors has, however, remained a challenging and relatively unexplored problem. A promising approach for the realization of such a state is to use excitons, bound pairs of electrons and holes that can form in semiconductor systems. At low densities, excitons are Bose-particles5, and at low temperatures, of the order of a few kelvin, excitons can form a quantum liquid—that is, a statistically degenerate Bose gas or even a Bose–Einstein condensate5,6,7. Here we report photoluminescence measurements of a quasi-two-dimensional exciton gas in GaAs/AlGaAs coupled quantum wells and the observation of a macroscopically ordered exciton state. Our spatially resolved measurements reveal fragmentation of the ring-shaped emission pattern into circular structures that form periodic arrays over lengths up to 1 mm.

Recombination: Multiply infected spleen cells in HIV patients.

Abstract: The genome of the human immunodeficiency virus is highly prone to recombination, although it is not obvious whether recombinants arise infrequently or whether they are constantly being spawned but escape identification because of the massive and rapid turnover of virus particles. Here we use fluorescence in situ hybridization to estimate the number of proviruses harboured by individual splenocytes from two HIV patients, and determine the extent of recombination by sequencing amplified DNA from these cells. We find an average of three or four proviruses per cell and evidence for huge numbers of recombinants and extensive genetic variation. Although this creates problems for phylogenetic analyses, which ignore recombination effects, the intracellular variation may help to broaden immune recognition.

Intercomparison of the climatological variations of Asian summer monsoon precipitation simulated by 10 GCMs

Abstract: We assesses the overall performance of state-of-the-art atmospheric GCMs in simulating the climatological variations of summer monsoon rainfall over the Asian-Western Pacific region and the systematic errors that are common to a group of GCMs. The GCM data utilized are obtained from 10 GCM groups participated in the CLIVAR/Monsoon GCM Intercomparison Project. The model composite shows that the overall spatial pattern of summer monsoon rainfall is similar to the observed, although the western Pacific rainfall is relatively weak. For the simulated precipitation over the western Pacific, the models can be classified into two categories. The first category of models simulates the precipitation more confined to the equatorial region and weaker precipitation in the subtropical western Pacific compared to the observed. The second category of models simulates large precipitation in the subtropical western Pacific but the region is shifted to the north by 5–10°. None of the models realistically reproduce the observed Mei-yu rain band in the region from the East China Sea to the mid Pacific. Most of the models produce a rain band along the continental side of East Asia. The climatological variations of simulated summer rainfall are examined in terms of their amplitude and their principal EOF modes. All models simulate larger amplitudes of the climatological seasonal variation of Indian summer monsoon than the observed, though most models simulate smaller amplitudes in the western Pacific. The ten model composite produces four leading EOF modes over the Asian-western Pacific region, which are remarkably similar to the observed counterparts. The first and second eigenmodes, respectively, represent the smoothed seasonal march of broad-scale monsoon and the onsets of the Indian and East Asian summer monsoon. The third and fourth modes relate to the climatological intraseasonal oscillation (CISO). In contrast to the model composite, several models fail to reproduce the first principal mode, and most models do not reproduce the observed modes higher than the second. The CISO of precipitation is also examined over the Indian monsoon and the East Asia-western Pacific monsoon regions separately.

Whispering-gallery waves

Abstract: A review of the theory of the natural waves (eigen-modes) in a dielectric sphere is presented. A special attention is paid to the eigenmodes with large radial and azimuthal indices, the so-called whispering-gallery modes. The experimental results of the spectroscopic study of modes in a dielectric sphere are reported. The fields of applications of whispering-gallery modes are discussed.

Harder than diamond: Dreams and reality

Abstract: Analysis of correlations between various physical properties of solids provides a formulation of simple criteria applicable to the search for new superhard materials. The prospects for the synthesis of new substances with the key elastic moduli, whose values approach or even exceed those of diamond are also discussed. We introduce the concept of ideal hardness and strength, which relates the elastic properties of materials to the corresponding mechanical characteristics, the concepts that are less unambiguously determined and that depend on the conditions of measurements. The control of material nanostructure makes it possible to approach the ideal hardness. The formulation of trends interrelating physical properties is expected to allow an essential guidance in the synthesis of new classes of superhard materials.

Elasticity of Polymer Networks

Abstract: We develop and solve a new molecular model for nonlinear elasticity of entangled polymer networks. This model combines and generalizes several succeseful ideas introduced over the years in the field of the rubber elasticity. The topological constraints imposed by the neighboring network chains on a given network are represented by the confining potential that changes upon network deformation. This topological potential restricts fluctuations of the network chain to the nonaffinely deformed confining tube. Network chains are allowed to fluctuate and redistribute their length along the contour of their confining tubes. The dependence of the stress σ on the elongation coefficient λ for the uniaxially deformed network is usially represented in the form of the Mooney stress, f*(1/λ) = σ/(λ − 1/λ2). We find a simple expression for the Mooney stress, f*(1/λ) = Gc + Ge/(0.74λ + 0.61λ-1/2 − 0.35), where Gc and Ge are phantom and entangled network moduli. This allows one to analyze the experimental data in the form...

Solar neutrino flux measurements by the Soviet-American gallium experiment (SAGE) for half the 22-year solar cycle

Abstract: We present measurements of the solar neutrino capture rate on metallic gallium in the Soviet-American gallium experiment (SAGE) over a period of slightly more than half the 22-year solar cycle. A combined analysis of 92 runs over the twelve-year period from January 1990 until December 2001 yields a capture rate of 70.8 −5.2 +5.3 (stat) −3.2 +3.7 (sys) SNU for solar neutrinos with energies above 0.233 MeV. This value is slightly more than half the rate predicted by the standard solar model, 130 SNU. We present the results of new runs since April 1998 and analyze all runs combined by years, months, and bimonthly periods beginning in 1990. A simple analysis of the SAGE results together with the results of other solar neutrino experiments gives an estimate of (4.6±1.2)× 1010 neutrinos cm−2 s−1 for the flux of the electron pp neutrinos that reach the Earth without changing their flavor. The flux of the pp neutrinos produced in thermonuclear reactions in the Sun is estimated to be (7.6 ± 2.0) × 1010 neutrinos cm−2 s−1, in agreement with the value of (5.95±0.06)×1010 neutrinos cm−2 s−1 predicted by the standard solar model.