Institution
University of Colorado Boulder
Education•Boulder, Colorado, United States•
About: University of Colorado Boulder is a education organization based out in Boulder, Colorado, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 48794 authors who have published 115151 publications receiving 5387328 citations. The organization is also known as: CU Boulder & UCB.
Topics: Population, Galaxy, Context (language use), Poison control, Stars
Papers published on a yearly basis
Papers
More filters
TL;DR: Some of the different approaches to community profiling are discussed, highlighting strengths and weaknesses of various experimental approaches, sequencing methodologies, and analytical methods and addressing one key question emerging from various Human Microbiome Projects.
Abstract: High-throughput sequencing studies and new software tools are revolutionizing microbial community analyses, yet the variety of experimental and computational methods can be daunting. In this review, we discuss some of the different approaches to community profiling, highlighting strengths and weaknesses of various experimental approaches, sequencing methodologies, and analytical methods. We also address one key question emerging from various Human Microbiome Projects: Is there a substantial core of abundant organisms or lineages that we all share? It appears that in some human body habitats, such as the hand and the gut, the diversity among individuals is so great that we can rule out the possibility that any species is at high abundance in all individuals: It is possible that the focus should instead be on higher-level taxa or on functional genes instead.
895 citations
Fox Chase Cancer Center1, University of Utah2, University of Texas MD Anderson Cancer Center3, University of California, San Diego4, University of South Florida5, Brigham and Women's Hospital6, University of Alabama at Birmingham7, Roswell Park Cancer Institute8, Case Western Reserve University9, Ohio State University10, University of Colorado Boulder11, University of Nebraska Medical Center12, Johns Hopkins University13, University of California, San Francisco14, University Of Tennessee System15, City of Hope National Medical Center16, University of Washington17, Duke University18, Northwestern University19, Memorial Sloan Kettering Cancer Center20
TL;DR: This portion of the NCCN Guidelines discusses general principles for the diagnosis, staging, and treatment of STS of the extremities, superficial trunk, or head and neck; outlines treatment recommendations by disease stage; and reviews the evidence to support the guidelines recommendations.
Abstract: Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for STS provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumors, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines discusses general principles for the diagnosis, staging, and treatment of STS of the extremities, superficial trunk, or head and neck; outlines treatment recommendations by disease stage; and reviews the evidence to support the guidelines recommendations.
894 citations
University of Texas MD Anderson Cancer Center1, University of South Florida2, University of California, San Francisco3, Harvard University4, University of North Carolina at Chapel Hill5, University of Colorado Boulder6, University of Michigan7, Memorial Sloan Kettering Cancer Center8, Georgetown University9, Roswell Park Cancer Institute10, Emory University11, Stanford University12, Cleveland Clinic13, University of Pittsburgh14, New York University15, Bristol-Myers Squibb16, City of Hope National Medical Center17
TL;DR: Nivolumab combined with ipilimumab had clinically meaningful intracranial efficacy, concordant with extracranial activity, in patients with melanoma who had untreated brain metastases.
Abstract: Background Brain metastases are a common cause of disabling neurologic complications and death in patients with metastatic melanoma. Previous studies of nivolumab combined with ipilimumab ...
894 citations
National Autonomous University of Mexico1, University of Illinois at Urbana–Champaign2, Conservation International3, German Primate Center4, Yale University5, University of Texas at Austin6, Oxford Brookes University7, Leibniz Institute for Neurobiology8, University of Colorado Boulder9, Durham University10, Emory University11, Naturhistorisches Museum12, Universidade Federal de Sergipe13, Federal University of Bahia14, Rhodes College15, University of Notre Dame16, Saint Louis University17, Northwestern University18, Federal University of Paraná19, University of Amsterdam20, Liverpool John Moores University21, Washington University in St. Louis22, University of Western Australia23, Chinese Academy of Sciences24
TL;DR: Raising global scientific and public awareness of the plight of the world’s primates and the costs of their loss to ecosystem health and human society is imperative.
Abstract: Nonhuman primates, our closest biological relatives, play important roles in the livelihoods, cultures, and religions of many societies and offer unique insights into human evolution, biology, behavior, and the threat of emerging diseases. They are an essential component of tropical biodiversity, contributing to forest regeneration and ecosystem health. Current information shows the existence of 504 species in 79 genera distributed in the Neotropics, mainland Africa, Madagascar, and Asia. Alarmingly, ~60% of primate species are now threatened with extinction and ~75% have declining populations. This situation is the result of escalating anthropogenic pressures on primates and their habitats—mainly global and local market demands, leading to extensive habitat loss through the expansion of industrial agriculture, large-scale cattle ranching, logging, oil and gas drilling, mining, dam building, and the construction of new road networks in primate range regions. Other important drivers are increased bushmeat hunting and the illegal trade of primates as pets and primate body parts, along with emerging threats, such as climate change and anthroponotic diseases. Often, these pressures act in synergy, exacerbating primate population declines. Given that primate range regions overlap extensively with a large, and rapidly growing, human population characterized by high levels of poverty, global attention is needed immediately to reverse the looming risk of primate extinctions and to attend to local human needs in sustainable ways. Raising global scientific and public awareness of the plight of the world’s primates and the costs of their loss to ecosystem health and human society is imperative.
893 citations
TL;DR: The tensor product representation rests on a principled analysis of structure; it saturates gracefully as larger structures are represented; it permits recursive construction of complex representations from simpler ones; it extends naturally to continuous structures and continuous representational patterns.
893 citations
Authors
Showing all 49233 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yi Chen | 217 | 4342 | 293080 |
| Robert J. Lefkowitz | 214 | 860 | 147995 |
| Rob Knight | 201 | 1061 | 253207 |
| Charles A. Dinarello | 190 | 1058 | 139668 |
| Jie Zhang | 178 | 4857 | 221720 |
| David Haussler | 172 | 488 | 224960 |
| Bradley Cox | 169 | 2150 | 156200 |
| Gang Chen | 167 | 3372 | 149819 |
| Rodney S. Ruoff | 164 | 666 | 194902 |
| Menachem Elimelech | 157 | 547 | 95285 |
| Jay Hauser | 155 | 2145 | 132683 |
| Robert E. W. Hancock | 152 | 775 | 88481 |
| Robert Plomin | 151 | 1104 | 88588 |
| Thomas E. Starzl | 150 | 1625 | 91704 |
| Rajesh Kumar | 149 | 4439 | 140830 |