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Institution

University of Kiel

EducationKiel, Germany
About: University of Kiel is a education organization based out in Kiel, Germany. It is known for research contribution in the topics: Population & Crystal structure. The organization has 27816 authors who have published 57114 publications receiving 2061802 citations. The organization is also known as: Christian Albrechts University & Christian-Albrechts-Universität zu Kiel.


Papers
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Journal ArticleDOI
TL;DR: The asthma-COPD overlap syndrome is reviewed, showing an increasing awareness that many patients have features of both disorders.
Abstract: Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.

485 citations

Journal ArticleDOI
TL;DR: Intramural hemorrhage is associated with a clinical profile and prognosis similar to classic dissection and may be considered an ominous precursor of overt aortic dissection.
Abstract: Background Intramural hemorrhage (IMH) was recently identified at necropsy and anecdotally in vivo as a unique aortic syndrome (without entry and with no flap-like intraluminal component, such as overt aortic dissection). However, little is known about diagnosis, prognosis, and outcome of IMH. Methods and Results Between 1983 and 1993, 360 patients from two medical centers with clinical indications of aortic dissection were prospectively evaluated; they presented to the emergency department a median of 3.5 hours after onset of back or chest pain or other suggestive symptoms. Among 195 patients with aortic syndromes, 25 patients (12.8%) were diagnosed to have IMH of the thoracic aorta with no evidence of a primary intimal tear, flap, or overt dissection by multiple noninvasive imaging modalities, including magnetic resonance imaging (n=12), contrast-enhanced computed tomography (n=14), and transesophageal echocardiography (n=3) in random order. There were 16 men and 9 women with a median age of 56±13 years...

485 citations

Journal ArticleDOI
TL;DR: A two-compartment diffusion model was found to adequately describe a standard SCR shape based on the process of sweat diffusion and nonnegative deconvolution is used to decompose SC data into discrete compact responses.
Abstract: Skin conductance (SC) data are usually characterized by a sequence of overlapping phasic skin conductance responses (SCRs) overlying a tonic component. The variability of SCR shapes hereby complicates the proper decomposition of SC data. A method is proposed for full decomposition of SC data into tonic and phasic components. A two-compartment diffusion model was found to adequately describe a standard SCR shape based on the process of sweat diffusion. Nonnegative deconvolution is used to decompose SC data into discrete compact responses and at the same time assess deviations from the standard SCR shape, which could be ascribed to the additional process of pore opening. Based on the result of single non-overlapped SCRs, response parameters can be estimated precisely as shown in a paradigm with varying inter-stimulus intervals.

484 citations

Journal ArticleDOI
TL;DR: Patients with PHN have been studied using quantitative testing of primary afferent function, skin biopsies, and controlled treatment trials to provide a preliminary glimpse of the pain-generating mechanisms in PHN.

484 citations

Journal ArticleDOI
31 May 2013-Science
TL;DR: Measurements of the energetic particle radiation environment inside the spacecraft during its cruise to Mars confirm the hazard likely to be posed by this radiation to astronauts on a future potential trip to Mars, and provide insights into the radiation hazards that would be associated with a human mission to Mars.
Abstract: The Mars Science Laboratory spacecraft, containing the Curiosity rover, was launched to Mars on 26 November 2011, and for most of the 253-day, 560-million-kilometer cruise to Mars, the Radiation Assessment Detector made detailed measurements of the energetic particle radiation environment inside the spacecraft. These data provide insights into the radiation hazards that would be associated with a human mission to Mars. We report measurements of the radiation dose, dose equivalent, and linear energy transfer spectra. The dose equivalent for even the shortest round-trip with current propulsion systems and comparable shielding is found to be 0.66 ± 0.12 sievert.

482 citations


Authors

Showing all 28103 results

NameH-indexPapersCitations
Stefan Schreiber1781233138528
Jun Wang1661093141621
William J. Sandborn1621317108564
Jens Nielsen1491752104005
Tak W. Mak14880794871
Annette Peters1381114101640
Severine Vermeire134108676352
Peter M. Rothwell13477967382
Dusan Bruncko132104284709
Gideon Bella129130187905
Dirk Schadendorf1271017105777
Neal L. Benowitz12679260658
Thomas Schwarz12370154560
Meletios A. Dimopoulos122137171871
Christian Weber12277653842
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023197
2022421
20212,761
20202,644
20192,556
20182,247