Institution
University of Macau
Education•Macao, Macau, China•
About: University of Macau is a education organization based out in Macao, Macau, China. It is known for research contribution in the topics: Computer science & Population. The organization has 6636 authors who have published 18324 publications receiving 327384 citations. The organization is also known as: UM & UMAC.
Papers published on a yearly basis
Papers
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TL;DR: A new two-dimensional Sine Logistic modulation map (2D-SLMM) which is derived from the Logistic and Sine maps is introduced which has the wider chaotic range, better ergodicity, hyperchaotic property and relatively low implementation cost.
585 citations
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582 citations
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TL;DR: The progress of PGPR for remediation of soils contaminated with organic and heavy metal pollutants is reviewed.
559 citations
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TL;DR: Examining leukocyte and cytokine activity in COVID‐19 focuses on how these levels are altered as the disease progresses and proposed consequences to organ pathology and Viral and host interactions are described to gain further insight into leukocytes biology and how dysregulated cytokine responses lead to disease and/or organ damage.
Abstract: Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway capacity and multi-organ failure-both of which are associated with the hyperproduction of cytokines, also known as a cytokine storm or cytokine release syndrome. Clinical reports show that both mild and severe forms of disease result in changes in circulating leukocyte subsets and cytokine secretion, particularly IL-6, IL-1s, IL-10, TNF, GM-CSF, IP-10 (IFN-induced protein 10), IL-17, MCP-3, and IL-1ra. Not surprising, therapies that target the immune response and curtail the cytokine storm in coronavirus 2019 (COVID-19) patients have become a focus of recent clinical trials. Here we review reports on leukocyte and cytokine data associated with COVID-19 disease in 3939 patients in China and describe emerging data on immunopathology. With an emphasis on immune modulation, we also look at ongoing clinical studies aimed at blocking proinflammatory cytokines; transfer of immunosuppressive mesenchymal stem cells; use of convalescent plasma transfusion; as well as immunoregulatory therapy and traditional Chinese medicine regimes. In examining leukocyte and cytokine activity in COVID-19, we focus in particular on how these levels are altered as the disease progresses (neutrophil NETosis, macrophage, T cell response, etc.) and proposed consequences to organ pathology (coagulopathy, etc.). Viral and host interactions are described to gain further insight into leukocyte biology and how dysregulated cytokine responses lead to disease and/or organ damage. By better understanding the mechanisms that drive the intensity of a cytokine storm, we can tailor treatment strategies at specific disease stages and improve our response to this worldwide public health threat.
541 citations
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TL;DR: A new approach is advocate that, for selected groups of taxa, combines the best use of single‐locus barcodes and super‐barcodes for efficient plant identification, and discusses the feasibility of using the chloroplast genome as a super-barcode.
Abstract: DNA barcoding is currently a widely used and effective tool that enables rapid and accurate identification of plant species; however, none of the available loci work across all species Because single-locus DNA barcodes lack adequate variations in closely related taxa, recent barcoding studies have placed high emphasis on the use of whole-chloroplast genome sequences which are now more readily available as a consequence of improving sequencing technologies While chloroplast genome sequencing can already deliver a reliable barcode for accurate plant identification it is not yet resource-effective and does not yet offer the speed of analysis provided by single-locus barcodes to unspecialized laboratory facilities Here, we review the development of candidate barcodes and discuss the feasibility of using the chloroplast genome as a super-barcode We advocate a new approach for DNA barcoding that, for selected groups of taxa, combines the best use of single-locus barcodes and super-barcodes for efficient plant identification Specific barcodes might enhance our ability to distinguish closely related plants at the species and population levels
536 citations
Authors
Showing all 6766 results
Name | H-index | Papers | Citations |
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Henry T. Lynch | 133 | 925 | 86270 |
Chu-Xia Deng | 125 | 444 | 57000 |
H. Vincent Poor | 109 | 2116 | 67723 |
Peng Chen | 103 | 918 | 43415 |
George F. Gao | 102 | 793 | 82219 |
MengChu Zhou | 96 | 1124 | 36969 |
Gang Li | 93 | 486 | 68181 |
Rob Law | 81 | 714 | 31002 |
Zongjin Li | 80 | 630 | 22103 |
Han-Ming Shen | 80 | 237 | 27410 |
Heng Li | 79 | 745 | 23385 |
Lionel M. Ni | 75 | 466 | 28770 |
C. L. Philip Chen | 74 | 482 | 20223 |
Chun-Su Yuan | 72 | 397 | 21089 |
Joao P. Hespanha | 72 | 418 | 39004 |