Institution
University of Macau
Education•Macao, Macau, China•
About: University of Macau is a education organization based out in Macao, Macau, China. It is known for research contribution in the topics: Computer science & Population. The organization has 6636 authors who have published 18324 publications receiving 327384 citations. The organization is also known as: UM & UMAC.
Papers published on a yearly basis
Papers
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TL;DR: The potential of sirtuin 1 as a therapeutic target for treating alcoholic and nonalcoholic fatty liver diseases is discussed and the latest advances of the biological roles of SIRT1 in regulating lipid metabolism, oxidative stress and inflammation in the liver are summarized.
Abstract: Fatty liver diseases, which are commonly associated with high-fat/calorie diet, heavy alcohol consumption and/or other metabolic disorder causes, lead to serious medical concerns worldwide in recent years. It has been demonstrated that metabolic homeostasis disruption is most likely to be responsible for this global epidemic. Sirtuins are a group of conserved nicotinamide adenine dinucleotide (NAD+) dependent histone and/or protein deacetylases belonging to the silent information regulator 2 (Sir2) family. Among seven mammalian sirtuins, sirtuin 1 (SIRT 1) is the most extensively studied one and is involved in both alcoholic and nonalcoholic fatty liver diseases. SIRT1 plays beneficial roles in regulating hepatic lipid metabolism, controlling hepatic oxidative stress and mediating hepatic inflammation through deacetylating some transcriptional regulators against the progression of fatty liver diseases. Here we summarize the latest advances of the biological roles of SIRT1 in regulating lipid metabolism, oxidative stress and inflammation in the liver, and discuss the potential of SIRT1 as a therapeutic target for treating alcoholic and nonalcoholic fatty liver diseases.
209 citations
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TL;DR: This work presents a meta-analysis of the putative mechanisms behind the Evolutionary Relationship of the Putative SmCPS1- and SmC PS2- Gene Clusters and co-Expression Analysis of CYPs with SmCps1 and 437 Putative CYPs in the S. miltiorrhiza Genome.
209 citations
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11 Jul 2011TL;DR: In this article, a combination of a recently developed Accelerated PSO and a nonlinear support vector machine (SVM) is used for solving business optimization problems, and the proposed SVM is applied to production optimization, and then used for income prediction and project scheduling.
Abstract: Business optimization is becoming increasingly important because all business activities aim to maximize the profit and performance of products and services, under limited resources and appropriate constraints. Recent developments in support vector machine and metaheuristics show many advantages of these techniques. In particular, particle swarm optimization is now widely used in solving tough optimization problems. In this paper, we use a combination of a recently developed Accelerated PSO and a nonlinear support vector machine to form a framework for solving business optimization problems. We first apply the proposed APSO-SVM to production optimization, and then use it for income prediction and project scheduling. We also carry out some parametric studies and discuss the advantages of the proposed metaheuristic SVM.
209 citations
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TL;DR: In this article, a mesoscopic hole transporter with active areas of 31 cm2 and 70 cm2 with power conversion efficiencies of 10.46% and 10.74% was fabricated using scalable printing processes.
Abstract: Monolithic perovskite modules with active areas of 31 cm2 and 70 cm2 and with power conversion efficiencies (PCE) of 10.46% and 10.74%, respectively, were fabricated using scalable printing processes. An ambient stability of more than 2000 h with less than a 5% reduction in efficiency is demonstrated. The electrical quality of the mesoscopic hole transporter and its facilitation of efficient infiltration is paramount.
208 citations
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TL;DR: A review of the latest literature on the development of CRG-based pharmaceutical vehicles and the perspective of using CRG for broader biomedical applications focuses on how current strategies exploit the unique gelling mechanisms, strong water absorption and abundant functional groups of the three major CRG varieties.
208 citations
Authors
Showing all 6766 results
Name | H-index | Papers | Citations |
---|---|---|---|
Henry T. Lynch | 133 | 925 | 86270 |
Chu-Xia Deng | 125 | 444 | 57000 |
H. Vincent Poor | 109 | 2116 | 67723 |
Peng Chen | 103 | 918 | 43415 |
George F. Gao | 102 | 793 | 82219 |
MengChu Zhou | 96 | 1124 | 36969 |
Gang Li | 93 | 486 | 68181 |
Rob Law | 81 | 714 | 31002 |
Zongjin Li | 80 | 630 | 22103 |
Han-Ming Shen | 80 | 237 | 27410 |
Heng Li | 79 | 745 | 23385 |
Lionel M. Ni | 75 | 466 | 28770 |
C. L. Philip Chen | 74 | 482 | 20223 |
Chun-Su Yuan | 72 | 397 | 21089 |
Joao P. Hespanha | 72 | 418 | 39004 |