Institution
Wageningen University and Research Centre
Education•Wageningen, Netherlands•
About: Wageningen University and Research Centre is a education organization based out in Wageningen, Netherlands. It is known for research contribution in the topics: Population & Sustainability. The organization has 23474 authors who have published 54833 publications receiving 2608897 citations.
Topics: Population, Sustainability, Agriculture, Climate change, Gene
Papers published on a yearly basis
Papers
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TL;DR: The increased knowledge base underpinning the development of GM crops will provide greater confidence in the assurances plant science can give on the risks of releasing such crops, and when assessing GM crops relative to existing cultivars.
Abstract: Despite numerous future promises, there is a multitude of concerns about the impact of GM crops on the environment. Key issues in the environmental assessment of GM crops are putative invasiveness, vertical or horizontal gene flow, other ecological impacts, effects on biodiversity and the impact of presence of GM material in other products. These are all highly interdisciplinary and complex issues. A crucial component for a proper assessment is defining the appropriate baseline for comparison and decision. For GM crops, the best and most appropriately defined reference point is the impact of plants developed by traditional breeding. The latter is an integral and accepted part of agriculture. In many instances, the putative impacts identified for GM crops are very similar to the impacts of new cultivars derived from traditional breeding. When assessing GM crops relative to existing cultivars, the increased knowledge base underpinning the development of GM crops will provide greater confidence in the assurances plant science can give on the risks of releasing such crops.
603 citations
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TL;DR: The effects of probiotic consumption on the intestinal microbiota are addressed, as well as the development of tailor-made probiotics designed for specific aberrations that are associated with microbial dysbiosis.
Abstract: The complex communities of microorganisms that colonise the human gastrointestinal tract play an important role in human health. The development of culture-independent molecular techniques has provided new insights in the composition and diversity of the intestinal microbiota. Here, we summarise the present state of the art on the intestinal microbiota with specific attention for the application of high-throughput functional microbiomic approaches to determine the contribution of the intestinal microbiota to human health. Moreover, we review the association between dysbiosis of the microbiota and both intestinal and extra-intestinal diseases. Finally, we discuss the potential of probiotic microorganism to modulate the intestinal microbiota and thereby contribute to health and well-being. The effects of probiotic consumption on the intestinal microbiota are addressed, as well as the development of tailor-made probiotics designed for specific aberrations that are associated with microbial dysbiosis.
600 citations
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University of Birmingham1, University of Reading2, Met Office3, City College of New York4, Wageningen University and Research Centre5, Potsdam Institute for Climate Impact Research6, University of Nottingham7, Max Planck Society8, University of Tokyo9, National Institute for Environmental Studies10, Utrecht University11, University of Bonn12, University of New Hampshire13
TL;DR: This study demonstrates that different representations of terrestrial water-cycle processes in GIMs are responsible for a much larger uncertainty in the response of hydrological drought to climate change than previously thought.
Abstract: Increasing concentrations of greenhouse gases in the atmosphere are expected to modify the global water cycle with significant consequences for terrestrial hydrology. We assess the impact of climate change on hydrological droughts in a multimodel experiment including seven global impact models (GIMs) driven by bias-corrected climate from five global climate models under four representative concentration pathways (RCPs). Drought severity is defined as the fraction of land under drought conditions. Results show a likely increase in the global severity of hydrological drought at the end of the 21st century, with systematically greater increases for RCPs describing stronger radiative forcings. Under RCP8.5, droughts exceeding 40% of analyzed land area are projected by nearly half of the simulations. This increase in drought severity has a strong signal-to-noise ratio at the global scale, and Southern Europe, the Middle East, the Southeast United States, Chile, and South West Australia are identified as possible hotspots for future water security issues. The uncertainty due to GIMs is greater than that from global climate models, particularly if including a GIM that accounts for the dynamic response of plants to CO2 and climate, as this model simulates little or no increase in drought frequency. Our study demonstrates that different representations of terrestrial water-cycle processes in GIMs are responsible for a much larger uncertainty in the response of hydrological drought to climate change than previously thought. When assessing the impact of climate change on hydrology, it is therefore critical to consider a diverse range of GIMs to better capture the uncertainty.
600 citations
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Vienna University of Technology1, CINVESTAV2, Broad Institute3, University of Salamanca4, Instituto Potosino de Investigación Científica y Tecnológica5, Technion – Israel Institute of Technology6, Bhabha Atomic Research Centre7, University of Szeged8, Joint Genome Institute9, University of Missouri–Kansas City10, French Institute of Health and Medical Research11, Macquarie University12, Technical University of Berlin13, Texas A&M University14, University of Debrecen15, Spanish National Research Council16, Centre national de la recherche scientifique17, Aalborg University18, French Institute of Petroleum19, International Sleep Products Association20, Wageningen University and Research Centre21, Pacific Northwest National Laboratory22
TL;DR: A better understanding of mycoparasitism is offered, and the development of improved biocontrol strains for efficient and environmentally friendly protection of plants is enforced.
Abstract: Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus, has special relevance when the prey is a plant pathogen, providing a strategy for biological control of pests for plant protection. Probably, the most studied biocontrol agents are species of the genus Hypocrea/Trichoderma. Here we report an analysis of the genome sequences of the two biocontrol species Trichoderma atroviride (teleomorph Hypocrea atroviridis) and Trichoderma virens (formerly Gliocladium virens, teleomorph Hypocrea virens), and a comparison with Trichoderma reesei (teleomorph Hypocrea jecorina). These three Trichoderma species display a remarkable conservation of gene order (78 to 96%), and a lack of active mobile elements probably due to repeat-induced point mutation. Several gene families are expanded in the two mycoparasitic species relative to T. reesei or other ascomycetes, and are overrepresented in non-syntenic genome regions. A phylogenetic analysis shows that T. reesei and T. virens are derived relative to T. atroviride. The mycoparasitism-specific genes thus arose in a common Trichoderma ancestor but were subsequently lost in T. reesei. The data offer a better understanding of mycoparasitism, and thus enforce the development of improved biocontrol strains for efficient and environmentally friendly protection of plants.
599 citations
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TL;DR: Targeted mutagenesis studies are unraveling the roles played in the infection process by a variety of B. cinerea genes that are required for penetration, host cell killing, plant tissue decomposition or signaling.
597 citations
Authors
Showing all 23851 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
Albert Hofman | 267 | 2530 | 321405 |
Frank B. Hu | 250 | 1675 | 253464 |
Willem M. de Vos | 148 | 670 | 88146 |
Willy Verstraete | 139 | 920 | 76659 |
Jonathan D. G. Jones | 129 | 417 | 80908 |
Bert Brunekreef | 124 | 806 | 81938 |
Pedro W. Crous | 115 | 809 | 51925 |
Marten Scheffer | 111 | 350 | 73789 |
Wim E. Hennink | 110 | 600 | 49940 |
Daan Kromhout | 108 | 453 | 55551 |
Peter H. Verburg | 107 | 464 | 34254 |
Marcel Dicke | 107 | 613 | 42959 |
Vincent W. V. Jaddoe | 106 | 1008 | 44269 |
Hao Wu | 105 | 669 | 42607 |