Journal ArticleDOI
Effects of Intermittent Fasting on Health, Aging, and Disease
Rafael de Cabo,Mark P. Mattson +1 more
TLDR
Effects of Intermittent Fasting on Health and Aging evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base fasting.Abstract:
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base...read more
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Journal ArticleDOI
Mitochondrial homeostasis: a potential target for delaying renal aging
Mingshu Yang,Chongbin Liu,Na Jiang,Yan Liu,Shilu Luo,Chenrui Li,Hao Zhao,Wei Jin Chen,Li Li,Li Xiao,Lixian Sun +10 more
TL;DR: In this paper , the role of abnormal mitochondrial homeostasis in renal aging has been reviewed in detail, and the current antiaging compounds that target mitochondria and note that maintaining mitochondria is a potential strategy against renal aging.
Journal Article
First Report Of 50-Day Continuous Fasting in Symptomatic Multivessel Coronary Artery Disease and Heart Failure: Cardioprotection Through Natural Ketosis.
TL;DR: In this paper , a 64-year-old man with angina and dyspnea due to severe two vessel coronary artery disease (CAD) was recommended for revascularization.
Journal ArticleDOI
Are the Modern Diets for the Treatment of Obesity Better than the Classical Ones?
TL;DR: The aim of the present review is to summarize the current state of evidence regarding the effects of these two popular modern diets, namely intermittent fasting and ketogenic diets, and to provide a concise update on their effects on body weight and cardiometabolic risk factors.
Journal ArticleDOI
Nutrition for precision health: The time is now
TL;DR: The evidence gathered from precision nutrition research will be the basis for constructing precision health dietary recommendations, which hold great promise to help individuals and their health care providers create precise and effective diet plans for precision health in the future.
Journal ArticleDOI
Early time‐restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis
Felicia L. Steger,Humaira Jamshed,David R. Bryan,Joshua S. Richman,Amy H. Warriner,Cody Hanick,Corby K. Martin,Sarah-Jeanne Salvy,Courtney M. Peterson +8 more
TL;DR: In this paper , the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed, and the results showed that intermittent fasting improves weight loss and cardiometabolic health.
References
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Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Ricki J. Colman,Rozalyn M. Anderson,Sterling C. Johnson,Erik K. Kastman,Kristopher J. Kosmatka,T. Mark Beasley,David B. Allison,Christina Cruzen,Heather A. Simmons,Joseph W. Kemnitz,Richard Weindruch +10 more
TL;DR: Findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research demonstrate that CR slows aging in a primate species.
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Risk of dementia in diabetes mellitus: a systematic review
TL;DR: The findings of mechanistic studies suggest that vascular disease and alterations in glucose, insulin, and amyloid metabolism underlie the pathophysiology of dementia, but which of these mechanisms are clinically relevant is unclear.
Journal ArticleDOI
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
Journal ArticleDOI
Starvation in man.
TL;DR: In this article, it was shown that decreased levels of active T3 may play a role by sparing otherwise obligated calories by decreasing metabolic needs, but this can be nullified by amino acid or protein supplementation.
Journal ArticleDOI
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network.
TL;DR: The results point to a central role for the PGC-1 family in integrating mitochondrial biogenesis and energy production with many diverse cellular functions.